scholarly journals Proteoglycan synthesis in bovine articular cartilage explants exposed to different low-frequency low-energy pulsed electromagnetic fields

2007 ◽  
Vol 15 (2) ◽  
pp. 163-168 ◽  
Author(s):  
M. De Mattei ◽  
M. Fini ◽  
S. Setti ◽  
A. Ongaro ◽  
D. Gemmati ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Electromagnetic Fields ◽  
Low Frequency ◽  
Low Energy ◽  
Cartilage Explants ◽  
Proteoglycan Synthesis ◽  
Pulsed Electromagnetic Fields ◽  
Bovine Articular Cartilage ◽  
Pulsed Electromagnetic

scholarly journals Adenosine Receptors as a Biological Pathway for the Anti-Inflammatory and Beneficial Effects of Low Frequency Low Energy Pulsed Electromagnetic Fields

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Katia Varani ◽  
Fabrizio Vincenzi ◽  
Annalisa Ravani ◽  
Silvia Pasquini ◽  
Stefania Merighi ◽  
...  
Keyword(s):  
Electromagnetic Fields ◽  
Adenosine Receptors ◽  
Biological Effects ◽  
Low Frequency ◽  
Low Energy ◽  
Membrane Receptors ◽  
Pulsed Electromagnetic Fields ◽  
Inflammatory Status ◽  
Anti Inflammatory ◽  
Pulsed Electromagnetic

Several studies explored the biological effects of low frequency low energy pulsed electromagnetic fields (PEMFs) on human body reporting different functional changes. Much research activity has focused on the mechanisms of interaction between PEMFs and membrane receptors such as the involvement of adenosine receptors (ARs). In particular, PEMF exposure mediates a significant upregulation ofA2Aand A3ARs expressed in various cells or tissues involving a reduction in most of the proinflammatory cytokines. Of particular interest is the observation that PEMFs, acting as modulators of adenosine, are able to increase the functionality of the endogenous agonist. By reviewing the scientific literature on joint cells, a double role for PEMFs could be hypothesized in vitro by stimulating cell proliferation, colonization of the scaffold, and production of tissue matrix. Another effect could be obtained in vivo after surgical implantation of the construct by favoring the anabolic activities of the implanted cells and surrounding tissues and protecting the construct from the catabolic effects of the inflammatory status. Moreover, a protective involvement of PEMFs on hypoxia damage in neuron-like cells and an anti-inflammatory effect in microglial cells have suggested the hypothesis of a positive impact of this noninvasive biophysical stimulus.

DNA Repair after γ Irradiation in Lymphocytes Exposed to Low-Frequency Pulsed Electromagnetic Fields

1989 ◽  
Vol 118 (1) ◽  
pp. 161 ◽  
Author(s):  
A. Cossarizza ◽  
D. Monti ◽  
P. Sola ◽  
G. Moschini ◽  
R. Cadossi ◽  
...  
Keyword(s):  
Dna Repair ◽  
Electromagnetic Fields ◽  
Low Frequency ◽  
Pulsed Electromagnetic Fields ◽  
Γ Irradiation ◽  
Pulsed Electromagnetic

scholarly journals Translational Insights into Extremely Low Frequency Pulsed Electromagnetic Fields (ELF-PEMFs) for Bone Regeneration after Trauma and Orthopedic Surgery

2019 ◽  
Vol 8 (12) ◽  
pp. 2028 ◽  
Author(s):  
Sabrina Ehnert ◽  
Steffen Schröter ◽  
Romina H. Aspera-Werz ◽  
Wiebke Eisler ◽  
Karsten Falldorf ◽  
...  
Keyword(s):  
Treatment Regimen ◽  
Electromagnetic Fields ◽  
Electrical Potential ◽  
Low Frequency ◽  
Treatment Modalities ◽  
Pulsed Electromagnetic Fields ◽  
Osteochondral Defects ◽  
Extremely Low Frequency ◽  
Pulsed Electromagnetic ◽  
Pemf Treatment

The finding that alterations in electrical potential play an important role in the mechanical stimulation of the bone provoked hype that noninvasive extremely low frequency pulsed electromagnetic fields (ELF-PEMF) can be used to support healing of bone and osteochondral defects. This resulted in the development of many ELF-PEMF devices for clinical use. Due to the resulting diversity of the ELF-PEMF characteristics regarding treatment regimen, and reported results, exposure to ELF-PEMFs is generally not among the guidelines to treat bone and osteochondral defects. Notwithstanding, here we show that there is strong evidence for ELF-PEMF treatment. We give a short, confined overview of in vitro studies investigating effects of ELF-PEMF treatment on bone cells, highlighting likely mechanisms. Subsequently, we summarize prospective and blinded studies, investigating the effect of ELF-PEMF treatment on acute bone fractures and bone fracture non-unions, osteotomies, spinal fusion, osteoporosis, and osteoarthritis. Although these studies favor the use of ELF-PEMF treatment, they likewise demonstrate the need for more defined and better controlled/monitored treatment modalities. However, to establish indication-oriented treatment regimen, profound knowledge of the underlying mechanisms in the sense of cellular pathways/events triggered is required, highlighting the need for more systematic studies to unravel optimal treatment conditions.

scholarly journals Pulse electromagnetic fields enhance the repair of rabbit articular cartilage defects with magnetic nano-hydrogel

RSC Advances ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 541-550 ◽  
Author(s):  
Jianghong Huang ◽  
Zhaofeng Jia ◽  
Yujie Liang ◽  
Zhiwang Huang ◽  
Zhibin Rong ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Articular Cartilage ◽  
Electromagnetic Fields ◽  
Cartilage Defects ◽  
Pulsed Electromagnetic Fields ◽  
Marrow Mesenchymal Stem Cells ◽  
Pulse Electromagnetic Fields ◽  
Pulsed Electromagnetic ◽  
Articular Cartilage Defects ◽  
Rabbit Articular Cartilage

Pulsed electromagnetic fields combined with magnetic nano-hydrogel can promote bone marrow mesenchymal stem cells to repair rabbit articular cartilage defects.

Effects of Electromagnetic Fields on Proteoglycan Metabolism of Bovine Articular Cartilage Explants

2003 ◽  
Vol 44 (3-4) ◽  
pp. 154-159 ◽  
Author(s):  
Monica De Mattei ◽  
Michela Pasello ◽  
Agnese Pellati ◽  
Giordano Stabellini ◽  
Leo Massari ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Electromagnetic Fields ◽  
Cartilage Explants ◽  
Bovine Articular Cartilage

Effects of extremely low-frequency pulsed electromagnetic fields (ELF-PEMFs) on glioblastoma cells (U87)

2016 ◽  
Vol 36 (3) ◽  
pp. 238-247 ◽  
Author(s):  
Zeinab Akbarnejad ◽  
Hossein Eskandary ◽  
Cristian Vergallo ◽  
Seyed Noureddin Nematollahi-Mahani ◽  
Luciana Dini ◽  
...  
Keyword(s):  
Electromagnetic Fields ◽  
Low Frequency ◽  
Pulsed Electromagnetic Fields ◽  
Glioblastoma Cells ◽  
Extremely Low Frequency ◽  
Pulsed Electromagnetic

Effects of Electromagnetic Fields on Proteoglycan Metabolism of Bovine Articular Cartilage Explants

2003 ◽  
Vol 44 (3) ◽  
pp. 154-159 ◽  
Author(s):  
Monica De Mattei ◽  
Michela Pasello ◽  
Agnese Pellati ◽  
Giordano Stabellini ◽  
Leo Massari ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Electromagnetic Fields ◽  
Cartilage Explants ◽  
Bovine Articular Cartilage
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