scholarly journals Pulse electromagnetic fields enhance the repair of rabbit articular cartilage defects with magnetic nano-hydrogel

RSC Advances ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 541-550 ◽  
Author(s):  
Jianghong Huang ◽  
Zhaofeng Jia ◽  
Yujie Liang ◽  
Zhiwang Huang ◽  
Zhibin Rong ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Articular Cartilage ◽  
Electromagnetic Fields ◽  
Cartilage Defects ◽  
Pulsed Electromagnetic Fields ◽  
Marrow Mesenchymal Stem Cells ◽  
Pulse Electromagnetic Fields ◽  
Pulsed Electromagnetic ◽  
Articular Cartilage Defects ◽  
Rabbit Articular Cartilage

Pulsed electromagnetic fields combined with magnetic nano-hydrogel can promote bone marrow mesenchymal stem cells to repair rabbit articular cartilage defects.

scholarly journals Pulsed electromagnetic fields promote repair of focal articular cartilage defects with engineered osteochondral constructs

2020 ◽  
Vol 117 (5) ◽  
pp. 1584-1596 ◽  
Author(s):  
Robert M. Stefani ◽  
Sofia Barbosa ◽  
Andrea R. Tan ◽  
Stefania Setti ◽  
Aaron M. Stoker ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Electromagnetic Fields ◽  
Cartilage Defects ◽  
Pulsed Electromagnetic Fields ◽  
Pulsed Electromagnetic ◽  
Articular Cartilage Defects

scholarly journals Repair of Articular Cartilage Defects using Bone Marrow Derived Mesenchymal Stem Cells in Rabbits

2019 ◽  
Vol 3 (1) ◽  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Single Dose ◽  
Articular Cartilage ◽  
Articular Surface ◽  
Cartilage Defects ◽  
Group Iii ◽  
Marrow Mesenchymal Stem Cells ◽  
Articular Cartilage Defects

The present study was performed to examine the effect of intra- articular injection of bone marrow mesenchymal stem cells (BMMSCs) and chondrogenic differentiated mesenchymal stem cells (CD- MSCs) on the repair of articular cartilage defects in rabbits. Twenty-five adult female baladi rabbits were used in this work. 5 rabbits were used for preparation of bone marrow mesenchymal stem cells (BM-MSCs) and their left knees were not subjected for the surgical procedure and used as normal control group. The remaining twenty rabbits were subjected for surgically induced cartilage defects in their left knees through a small medial parapatellar incision using bone curette. In the next day, the rabbits were divided into four groups: group I was not injected intraarticularly, group II injected intra-articularly by a single dose of saline, group III injected intra-articularly by a single dose of BM-MSCs and group IV injected intra-articularly by a single dose of CD-MSCs. After 8 weeks from the time of intra-articular injection. On time the rabbits were sacrificed and the entire knee joints were excised and examined. Groups I and II showed marked degenerative changes in their articular cartilage. The articular surface healed by fibrocartilage in group III, while in group IV the articular surface healed by hyaline cartilage. Treatment by CD-MSCs promotes a better healing effect on the articular cartilage defects of injured knee joints in rabbit’s model and has a remarkable superiority of repair than BM-MSCs. This can prevent the progress of cartilage defect into osteoarthritis which was a harmful disease.

In-advance trans-medullary stimulation of bone marrow enhances spontaneous repair of full-thickness articular cartilage defects in rabbits

2010 ◽  
Vol 341 (3) ◽  
pp. 371-379 ◽  
Author(s):  
Kazuya Nishizawa ◽  
Shinji Imai ◽  
Tomohiro Mimura ◽  
Mitsuhiko Kubo ◽  
Susumu Araki ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Articular Cartilage ◽  
Cartilage Defects ◽  
Full Thickness ◽  
Articular Cartilage Defects ◽  
Spontaneous Repair ◽  
Stimulation Of
Sign in / Sign up

Export Citation Format

Share Document