Study on the interaction of the antiviral drug, zidovudine with DNA using neutral red (NR) and methylene blue (MB) dyes

2013 ◽  
Vol 134 ◽  
pp. 629-634 ◽  
Author(s):  
Nahid Shahabadi ◽  
Neda Hossein pour Moghadam
Keyword(s):  
Methylene Blue ◽  
Antiviral Drug ◽  
Neutral Red

The effect of physico-chemically immobilized methylene blue and neutral red on the anode of microbial fuel cell

2012 ◽  
Vol 17 (2) ◽  
pp. 361-370 ◽  
Author(s):  
Arseniy L. Popov ◽  
Jung Rae Kim ◽  
Richard M. Dinsdale ◽  
Sandra R. Esteves ◽  
Alan J. Guwy ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Fuel Cell ◽  
Microbial Fuel Cell ◽  
Neutral Red

scholarly journals Experiments on the Effect of Dyes on Induction and Respiration in the Amphibian Gastrula

1939 ◽  
Vol 16 (2) ◽  
pp. 150-154
Author(s):  
R. A. BEATTY ◽  
S. DE JONG ◽  
M. A. ZIELIŃSKI
Keyword(s):  
Methylene Blue ◽  
Oxygen Consumption ◽  
Weak Solutions ◽  
Neural Differentiation ◽  
Neutral Red ◽  
Cell Respiration ◽  
Janus Green ◽  
Method Show ◽  
Weak Concentration

1. It is shown that pieces of presumptive epidermis (ventral ectoderm of the gastrula), when isolated into weak solutions of several dyes, will undergo neural differentiation. Dyes such as Janus green and neutral red, which are not known to accelerate cell respiration, appear to have this effect, as well as methylene blue, the accelerating action of which on cell respiration is well known. 2. Measurements of the oxygen consumption of isolated pieces of the gastrula by the Cartesian Diver method show that methylene blue, if in weak concentration, has an accelerating action of about 45%. In stronger concentrations it is inhibitory.

A simple technique for the preservation of vital dyes in fixed and sectioned embryos

Development ◽  
1966 ◽  
Vol 15 (2) ◽  
pp. 131-132
Author(s):  
J. Pertusa
Keyword(s):  
Methylene Blue ◽  
Ethyl Alcohol ◽  
Toluidine Blue ◽  
Trypan Blue ◽  
Simple Technique ◽  
Nile Blue ◽  
Neutral Red ◽  
The Other ◽  
Serial Sectioning ◽  
Vital Dyes

In embryological work using vital dyes it is highly desirable to be able to study the distribution of the dyes in fixed material, whether examined in toto or after embedding in paraffin and serial sectioning. However, both fixation and dehydration present problems for the preservation of colour in vitally stained cells. Some fixatives preserve some dyes but, so far as I am aware, none will preserve all the vital dyes in common use. On the other hand, ethyl alcohol destroys or dissolves all vital dyes and its use in dehydration is thus undesirable. Among the fixatives that have been proposed are those of Golowin (1902), Mitamura (1923), Parat & Painlevé (1925), and Tchéou Tai Chuin (1930) for neutral red; that of Izquierdo (1955) for toluidine blue; that of Gérard (1925) for Trypan blue; that of Turchini (1919) for methylene blue; that of Lehmann (1929) for Nile blue.

Properties of oral asaccharolytic black-pigmented Bacteroides

1984 ◽  
Vol 30 (9) ◽  
pp. 1133-1136 ◽  
Author(s):  
D. Mayrand ◽  
G. Bourgeau ◽  
D. Grenier ◽  
J.-M. Lacroix
Keyword(s):  
Methylene Blue ◽  
Congo Red ◽  
Neutral Red ◽  
Enzymatic Activities ◽  
The Other ◽  
Other Hand ◽  
Inhibitory Agents ◽  
Group B

Bacteroides endodontalis, a newly described asaccharolytic black-pigmented Bacteroides, along with the other two recognized species of this group (B. gingivalis and B. asaccharolyticus) were studied for their susceptibility to various dyes and inhibitory agents and for some of their enzymatic activities to facilitate differentiating between them. Bacteroides endodontalis resembles B. asaccharolyticus physiologically except for the fact that the former cannot grow on media containing methylene blue, neutral red, or 3% sodium choride, whereas B. asaccharolyticus can. On the other hand, B. endodontalis and B. gingivalis can grow on a medium containing Congo red while B. asaccharolyticus cannot.

scholarly journals In Vitro Antiviral Activity of Heterophyllaea pustulata Extracts

2012 ◽  
Vol 7 (8) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Brenda S. Konigheim ◽  
Mauricio Beranek ◽  
Laura R. Comini ◽  
Javier J. Aguilar ◽  
Juliana Marioni ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Antiviral Drug ◽  
Neutral Red ◽  
Type I ◽  
Saint Louis ◽  
Aerial Parts ◽  
Uptake Assay ◽  
Simplex Virus ◽  
Hsv 1

The antiviral activity was tested of different polarity extracts, with differing chemical composition, obtained from aerial parts of Heterophyllaea pustulata Hook f. (Rubiaceae) against Herpes Simplex Virus Type I (HSV-1) and Saint Louis Encephalitis Virus (SLEV). The Vero cell line was employed as a host cell for the antiviral assessment of benzene (Ben), ethyl acetate (EtOAc) and ethanol (EtOH) extracts by means of the Neutral Red uptake assay and plaque reduction test. None of the extracts showed antiviral activity against SLEV. Only the extracts (Ben and EtOAc) with a high content of anthraquinones (AQs) inhibited HSV-1 replication, exhibiting Selectivity Index (SI) values of 2.7 and 2.4, respectively. Therefore, these extracts could be good candidates as natural sources for antiviral drug development against HSV-1.

scholarly journals Spectroscopic Measurement of Methylene Blue Distribution in Organs and Tissues of Hamadryas Baboons during Oral Administration

Photonics ◽  
2021 ◽  
Vol 8 (8) ◽  
pp. 294
Author(s):  
Elizaveta I. Kozlikina ◽  
Daria V. Pominova ◽  
Anastasia V. Ryabova ◽  
Kanamat T. Efendiev ◽  
Aleksei S. Skobeltsin ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Oral Administration ◽  
Antiviral Drug ◽  
Spectroscopic Measurement ◽  
Cellular Damage ◽  
Autoimmune Response ◽  
Hamadryas Baboon ◽  
Cytokine Storm ◽  
Hamadryas Baboons ◽  
New Research

New research on Methylene Blue (MB), carried out in 2020, shows that it can be an effective antiviral drug as part of COVID-19 treatment. According to the research findings, MB has potential as a direct antiviral drug for the prevention and treatment of COVID-19 in the first stages of the disease. However, the MB accumulation by various types of tissues, as well as by immune cells, has not been previously studied. Therefore, the objective of this study was to obtain spectral data on the interstitial distribution of the administered drug in endothelial tissues in primates. The data on interstitial MB distribution obtained by spectroscopic measurement at both macro- and microlevels during oral administration to Hamadryas baboon individuals demonstrate that MB accumulates in mucous membranes of gastrointestinal tract and the tissues of the respiratory, cardiovascular, immune, and nervous systems. Additionally, it was found that MB was present in lung and brain myeloid cells in significant concentrations, which makes it potentially useful for protection from autoimmune response (cytokine storm) and as a tool for the correction of immunocompetent cells’ functional state during laser irradiation. Since the cytokine storm starts from monocytic cells during SARS-CoV-2 cellular damage and since tumor-associated macrophages can significantly alter tumor metabolism, accumulation of MB in these cells provides a reason to conclude that the immune response correction in COVID-19 patients and change in macrophages phenotype can be achieved by deactivation of inflammatory macrophages in tissues with MB using laser radiation of red spectral range.

Uptake of micropollutant-bisphenol A, methylene blue and neutral red onto a novel bagasse-β-cyclodextrin polymer by adsorption process

Chemosphere ◽  
2020 ◽  
Vol 259 ◽  
pp. 127439 ◽  
Author(s):  
Farid Mzee Mpatani ◽  
Aaron Albert Aryee ◽  
Alexander Nti Kani ◽  
Qiehui Guo ◽  
Evans Dovi ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Bisphenol A ◽  
Adsorption Process ◽  
Neutral Red ◽  
Cyclodextrin Polymer
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