scholarly journals Effect of storage time on metabolite profile and alpha-glucosidase inhibitory activity of Cosmos caudatus leaves – GCMS based metabolomics approach

2015 ◽  
Vol 23 (3) ◽  
pp. 433-441 ◽  
Author(s):  
Neda Javadi ◽  
Faridah Abas ◽  
Ahmed Mediani ◽  
Azizah Abd Hamid ◽  
Alfi Khatib ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Storage Time ◽  
Metabolite Profile ◽  
Cosmos Caudatus ◽  
Alpha Glucosidase

scholarly journals ALPHA AMYLASE AND ALPHA GLUCOSIDASE INHIBITION ACTIVITY OF SELECTED EDIBLE SEAWEEDS FROM SOUTH COAST AREA OF INDIA

2017 ◽  
Vol 9 (6) ◽  
pp. 64 ◽  
Author(s):  
P. Reka ◽  
Thahira Banu A. ◽  
M. Seethalakshmi
Keyword(s):  
Aqueous Extract ◽  
Inhibitory Activity ◽  
Alpha Amylase ◽  
Postprandial Blood Glucose ◽  
Inhibition Activity ◽  
Gracilaria Edulis ◽  
Edible Seaweeds ◽  
Daily Diet ◽  
Postprandial Blood Glucose Level ◽  
Alpha Glucosidase

Objective: The present work was to investigate the alpha amylase and alpha-glucosidase inhibitory activity of the selected edible seaweeds.Methods: The seaweeds namely Acanthophora spicifera, Gracilaria corticata, Gracilaria edulis, Ulva lactuca and Ulva reticulata were selected for this study. Six and eight hours of ethanol and aqueous extract were used for the estimation of alpha amylase using DNS method and alpha-glucosidase inhibition activity.Results: The study reported that the solvent from ethanol and aqueous in eight hours of extraction showed a higher inhibitory activity than six hours of extraction. Maximum of 89.1±0.96 and 79.55±3.08 percent of alpha-amylase and alpha-glucosidase inhibition activity were detected in the eight hours of aqueous extract (0.5 ml) of Ulva reticulata and Gracilaria edulis respectively. All the selected edible seaweeds had significant differences (p<0.05) in alpha amylase and alpha glucosidase inhibition activity between the selected seaweeds with different extracts.Conclusion: It was concluded that all the selected edible seaweeds have the potential to act as a potent inhibitor of the carbohydrate hydrolyzing enzyme. Thus, it was clear from the study that seaweeds incorporated in small amounts in the dishes consumed in the daily diet can bring a control on postprandial blood glucose level.

scholarly journals Nutritional Composition and .ALPHA.-Glucosidase Inhibitory Activity of Five Chinese Vinegars

2011 ◽  
Vol 45 (4) ◽  
pp. 445-456 ◽  
Author(s):  
JunFeng FAN ◽  
YanYan ZHANG ◽  
LinNa ZHOU ◽  
ZaiGui LI ◽  
BoLin ZHANG ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Nutritional Composition ◽  
Alpha Glucosidase

scholarly journals Antioxidant, anti-cholinesterase, anti-α-glucosidase and prebiotic properties of beta-glucan extracted from Algerian barley

2018 ◽  
Vol 10 (1) ◽  
pp. 58 ◽  
Author(s):  
Saad Mebrek ◽  
Hanene Djeghim ◽  
Yamina Mehdi ◽  
Asma Meghezzi ◽  
Sirajudheen Anwar ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Reducing Power ◽  
Beta Carotene ◽  
Moderate Activity ◽  
Beta Glucan ◽  
Antioxidant Power ◽  
Camel's Milk ◽  
Therapeutic Properties ◽  
Alpha Glucosidase ◽  
Low Activity

<p>Beta-glucan, such as barley-derived beta-glucan (BBG), are homopolysaccharides that have attracted attention by their nutritional and therapeutic properties. The aim of this study was to evaluate the antioxidant power of BBG extracted from local Algerian variety of barley (SAIDA 183), and its acetylcholinesterase, alpha glucosidase inhibitory activity as well as its prebiotic potential by fermentation with lactic acid bacteria isolated from camel’s milk, namely <em>lactococcuslactisssplactis</em> (Lc.l.l) and <em>leuconostocmesenteroidesspmesenteroides</em> (Ln.m.m). The results revealed that BBG exhibited low activity against DPPH and ferric-reducing power (IC<sub>50</sub> 4018.61 ± 656.69 and A<sub>0.5 </sub>at 359.88 ±63.64 µg/mL respectively), in contrast to other antioxidant tests (ABTS, Beta-carotene and CUPRAC) where BBG demonstrated a moderate activity (IC<sub>50</sub> 529.91 ±26.37, IC<sub>50</sub> 161.013±13.322, A<sub>0.5 </sub>529.79 ± 48.65 µg/mL). The scavenging ability of hydroxyl radical and superoxide radical by BBG with an IC<sub>50</sub> at 2268.38±101.57 µg/mL and IC<sub>50</sub> 345.26± 62.32 µg/mL, respectively, while enzymatic inhibition by  BBG exhibited for AChE at IC<sub>50</sub> 859.164 ±64.46 μg/mL , BChE at IC<sub>50</sub> at 725.470 ±30.95 , α-Amylase inhibitory activity at IC<sub>50</sub> 2986.785 ± 37.046  . The bacterial growth of the two strains used in this study is favorably affected by the use of BBG as the only carbon source, in comparison with glucose as a control. In light of these findings, it can be concluded that BBG have shown moderate antioxidant and enzyme inhibitory activities and can be used as a prebiotic by acting synergistically with probiotics in functional food matrices.</p>

Influence of Different Drying Treatments and Extraction Solvents on the Metabolite Profile and Nitric Oxide Inhibitory Activity of Ajwa Dates

2015 ◽  
Vol 80 (11) ◽  
pp. H2603-H2611 ◽  
Author(s):  
Nur Ashikin Abdul-Hamid ◽  
Faridah Abas ◽  
Intan Safinar Ismail ◽  
Khozirah Shaari ◽  
Nordin H. Lajis
Keyword(s):  
Nitric Oxide ◽  
Inhibitory Activity ◽  
Metabolite Profile ◽  
Extraction Solvents

scholarly journals Variation in the metabolites and α-glucosidase inhibitory activity of Cosmos caudatus at different growth stages

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Wan Ahmad Wan-Nadilah ◽  
Muhammad Tayyab Akhtar ◽  
Khozirah Shaari ◽  
Alfi Khatib ◽  
Azizah Abdul Hamid ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Growth Stages ◽  
Cosmos Caudatus ◽  
Different Growth Stages

scholarly journals A Novel Method for the Assay of .ALPHA.-Glucosidase Inhibitory Activity Using a Multi-channel Oxygen Sensor.

2002 ◽  
Vol 18 (12) ◽  
pp. 1315-1319 ◽  
Author(s):  
Kiyoshi MATSUMOTO ◽  
Kayoko TAKEMATA ◽  
Kiyofumi TAKAYAMA ◽  
Kanthi J. M. ABESUNDARA ◽  
Toshiro MATSUI ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Oxygen Sensor ◽  
Novel Method ◽  
Alpha Glucosidase
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