Characteristics of depressive patients according to family history of affective illness: Findings from a French national cohort

2016 ◽  
Vol 198 ◽  
pp. 15-22 ◽  
Author(s):  
J.M. Azorin ◽  
R. Belzeaux ◽  
E. Fakra ◽  
E.G. Hantouche ◽  
M. Adida
Keyword(s):  
Family History ◽  
Affective Illness ◽  
National Cohort ◽  
History Of ◽  
Depressive Patients

Life Events Precipitating Mania

1983 ◽  
Vol 142 (4) ◽  
pp. 398-403 ◽  
Author(s):  
Sidney Kennedy ◽  
Ruth Thompson ◽  
Harvey C. Stancer ◽  
Alec Roy ◽  
Emmanuel Persad
Keyword(s):  
Family History ◽  
Life Events ◽  
Social Relationships ◽  
Psychotropic Medication ◽  
Matched Control ◽  
Negative Impact ◽  
Fold Increase ◽  
Affective Illness ◽  
History Of ◽  
Manic Patients

SummaryA study of 20 manic patients, with patient and matched control comparisons, showed a two fold increase in life events during the 4 month period before admission to hospital. Life events, independent of affective illness and having significant objective negative impact (i.e. traumatic) were significantly more common. These findings are considered in relation to social relationships, family history of affective illness and the use of psychotropic medication.

Pre-Pubertal Depressive Stupor: A Case Report

1988 ◽  
Vol 153 (5) ◽  
pp. 689-692 ◽  
Author(s):  
J. C. Powell ◽  
W. R. Silveira ◽  
R. Lindsay
Keyword(s):  
Case Report ◽  
Family History ◽  
Affective Disorder ◽  
Dexamethasone Suppression Test ◽  
Clinical State ◽  
Affective Illness ◽  
History Of ◽  
Suppression Test ◽  
Dexamethasone Suppression ◽  
Maternal Side

A case of childhood affective disorder with episodes of depressive stupor in a 13-year-old pre-pubertal boy is described. Changes in the patient's clinical state were accompanied by changes in the dexamethasone suppression test. A family history of affective illness on the maternal side, with phenomenological similarities, is noted.

Do depressive patients with family history of dementia constitute a separate group? A case report study

2000 ◽  
Vol 4 (3) ◽  
pp. 215-222 ◽  
Author(s):  
Kostas N Fountoulakis ◽  
Fotis Fotiou ◽  
Apostolos Iacovides ◽  
George Kaprinis
Keyword(s):  
Case Report ◽  
Family History ◽  
Separate Group ◽  
History Of ◽  
Group A ◽  
Depressive Patients

Personal and family history of affective illness in patients with multiple sclerosis

1987 ◽  
Vol 12 (1) ◽  
pp. 63-65 ◽  
Author(s):  
Russell T. Joffe ◽  
Gerard P. Lippert ◽  
Trevor A. Gray ◽  
Gordon Sawa ◽  
Ziporah Horvath
Keyword(s):  
Multiple Sclerosis ◽  
Family History ◽  
Affective Illness ◽  
History Of

Onset of Mania in Bipolar Manic-Depressive Patients

1979 ◽  
Vol 13 (1) ◽  
pp. 57-61 ◽  
Author(s):  
G. F. S. Johnson ◽  
G. E. Hunt
Keyword(s):  
Family History ◽  
Positive Family History ◽  
Bipolar Illness ◽  
Illness Onset ◽  
Manic Depressive ◽  
History Of ◽  
Male Patients ◽  
Initial Episode ◽  
Depressive Patients

Onset of mania was evaluated retrospectively in 48 bipolar manic-depressive patients. Mania occurred as the initial episode in 40% of cases. In patients with initial episode of depression, approximately 80% developed mania prior to their third episode of depression and within 5 years from the onset of this illness. Differences in type of illness onset were related to family history of bipolar illness and sex of the proband. Male patients with a positive family history were significantly more likely to manifest mania at onset of illness.

Mania in the elderly

1989 ◽  
Vol 155 (2) ◽  
pp. 220-224 ◽  
Author(s):  
Kit Stone
Keyword(s):  
Retrospective Study ◽  
Family History ◽  
Affective Disorders ◽  
Age Of Onset ◽  
The Elderly ◽  
Prior History ◽  
Lithium Toxicity ◽  
Affective Illness ◽  
History Of

A retrospective study of 92 patients admitted with mania, aged over 65 years of age, found that 26% had no prior history of affective illness; 30% had previously only experienced depression, and half of these had at least three episodes of depression before the first manic illness. Patients with a family history of affective disorders had a significantly earlier age of onset of illness. There was evidence of cerebral organic impairment in 24% of the patients, and this group had a significantly later age of onset of illness. Prognosis was good, with only 8% still in hospital at six months. Half of the patients were started on lithium prophylaxis, but this did not significantly alter the number of readmissions. A quarter of those started on lithium developed evidence of lithium toxicity.

Family History of Venous Thromboembolism (VTE) and the Risk of VTE Recurrence in Patients with a First Unprovoked VTE: A Multicenter Prospective Cohort Study

Blood ◽  
2011 ◽  
Vol 118 (21) ◽  
pp. 2299-2299
Author(s):  
Karine Gauthier ◽  
Elham Sabri ◽  
Susan R. Kahn ◽  
Philip S Wells ◽  
David Anderson ◽  
...  
Keyword(s):  
Cohort Study ◽  
Venous Thromboembolism ◽  
Family History ◽  
Conflicts Of Interest ◽  
Anticoagulation Therapy ◽  
Degree Relative ◽  
National Cohort ◽  
History Of ◽  
Recurrent Vte ◽  
Second Degree

Abstract Abstract 2299 Introduction: The duration of anticoagulation after unprovoked venous thromboembolism (VTE) has been characterized as the most important unanswered question in clinical thrombosis management. This has led to research to identify predictors of recurrent VTE to identify high-risk patients who might warrant indefinite anticoagulation. Many clinicians assume that a family history of VTE is a predictor of recurrent VTE. This study aims to assess the value of family history as a predictor for recurrent VTE. Methods: Prospective multi-center multi-national cohort study recruited patients with a first objectively proven unprovoked VTE who completed 5 to 7 months of anticoagulation therapy. A detailed family history of VTE was completed for every subject. The information recorded included the number of affected relatives, whether they were first or second degree relatives and if the VTE was unprovoked or secondary. Patients were then followed for recurrent VTE. Results: 664 subjects were enrolled between October 2001 and March 2006, 649 subjects were followed for a mean duration of 3.8 years (3.6–3.98 95% C.I.). The mean age of subjects in this cohort was 53 years (min-max 18–95) and 49% of subjects were females. A family history of VTE in at least 1 first-degree relative was recorded for 112 (17.3%) subjects. A total of 142 (21.9%) suspected VTE events were adjudicated as recurrences. The recurrence rate was 5.94% (4.89–7.15 95% C.I.) per patient-year for patients without any family history of VTE, and it was 4.82% (3.02–7.30 95% C.I.) per patient-year in patients with a family history of VTE in at least 1 first-degree relative. In secondary analyses, neither a family history of unprovoked VTE, multiple unprovoked VTE, in first-degree nor second-degree relatives was a predictor of recurrent VTE. A multivariate analysis was performed to adjust for known risk factors for VTE recurrence, but the adjusted hazard ratios were again not significantly different. Conclusion: A family history of VTE is not a predictor for recurrent VTE, and therefore should not be used to segregate unprovoked VTE patients in high- and low-risk categories. Disclosures: No relevant conflicts of interest to declare.

A Genetic Study of Affective Disorder

1969 ◽  
Vol 115 (525) ◽  
pp. 917-922 ◽  
Author(s):  
Geoffrey Hopkinson ◽  
Philip Ley
Keyword(s):  
Family History ◽  
Lower Risk ◽  
Later Life ◽  
Affective Illness ◽  
Before And After ◽  
History Of ◽  
Morbidity Risk ◽  
First Time ◽  
Onset Group ◽  
Early Onset Group

It is well known that when affective illness has its onset in later life a family history of this illness is significantly less common than in cases where the onset is early. Thus, Kay (1959) compared cases in this respect before and after 60 years of age; the morbidity risk was 10–12·7 per cent for relatives of the early onset group and only 3·5–5·7 per cent in relatives of those falling ill for the first time after 60. Similarly, Hopkinson (1964), taking the age of 50 to divide his probands, found a significantly lower risk for affective illness in relatives of the older-onset probands.

Sign in / Sign up

Export Citation Format

Share Document