Life Events Precipitating Mania

1983 ◽  
Vol 142 (4) ◽  
pp. 398-403 ◽  
Author(s):  
Sidney Kennedy ◽  
Ruth Thompson ◽  
Harvey C. Stancer ◽  
Alec Roy ◽  
Emmanuel Persad

SummaryA study of 20 manic patients, with patient and matched control comparisons, showed a two fold increase in life events during the 4 month period before admission to hospital. Life events, independent of affective illness and having significant objective negative impact (i.e. traumatic) were significantly more common. These findings are considered in relation to social relationships, family history of affective illness and the use of psychotropic medication.

1996 ◽  
Vol 169 (6) ◽  
pp. 753-757 ◽  
Author(s):  
Alec Roy

BackgroundSecondary depression is common among primary alcoholics. However, its aetiology is poorly understood.MethodForty men with primary alcoholism, abstinent for two weeks or more, with a secondary major depressive episode were compared with forty matched never-depressed primary alcoholic controls for risk factors for depression and recent life events.ResultsIn the six months before the onset of depression depressed alcoholics had experienced significantly more life events, more life events with negative impact more dependent events caused by alcohol, and more independent events. Significantly more depressed alcoholics than controls had a family history of depression, a family history of suicidal behaviour and had themselves attempted suicide.ConclusionHaving recent life events, particularly events with negative impact, and a family history of depression are risk factors for secondary depression in alcoholics.


1981 ◽  
Vol 139 (1) ◽  
pp. 38-42 ◽  
Author(s):  
R. C. B. Aitken ◽  
J. A. Lister ◽  
C. J. Main

SummaryThe psychological and physiological features of 20 aircrew consecutively referred for treatment of anxiety symptoms when flying were compared with a matched control group of uncomplaining aircrew. There were no significant differences between the two groups on psychometric tests of personality, though there were differences in skin conductance; the phobics had a higher rate of spontaneous fluctuation, and habituated less to a repeated auditory tone. More of the phobic group worried about their wives and acknowledged childhood and other adulthood phobias; more had a family history of an episode perhaps best described as flying trauma. Many were on an overseas posting when symptoms presented. These few features could correctly classify 85 per cent of the subjects into the phobic or control group. This type of ‘phobic aircrew index’ now requires to be validated prospectively for its predictive value.


1971 ◽  
Vol 118 (547) ◽  
pp. 671-673 ◽  
Author(s):  
G. W. Mellsop ◽  
M. S. Spelman ◽  
A. W. Harrison

It can be difficult to make a confident diagnosis and one that will stand the test of time when a person without a family history or previous history of psychosis presents as psychotic with overactivity, pressure of talk, loose association of ideas and perhaps some paranoid ideation. He may be schizophrenic or manic. The nature of the disturbance of speech, and by inference thought, may assist in making the clinical diagnosis, but standard textbooks (Slater and Roth, 1969; Freedman and Kaplan, 1967) state that pressure of speech, flight of ideas, clang associations, distractibility and inability to adhere to a line of thought are common to both conditions.


1988 ◽  
Vol 153 (5) ◽  
pp. 689-692 ◽  
Author(s):  
J. C. Powell ◽  
W. R. Silveira ◽  
R. Lindsay

A case of childhood affective disorder with episodes of depressive stupor in a 13-year-old pre-pubertal boy is described. Changes in the patient's clinical state were accompanied by changes in the dexamethasone suppression test. A family history of affective illness on the maternal side, with phenomenological similarities, is noted.


1987 ◽  
Vol 12 (1) ◽  
pp. 63-65 ◽  
Author(s):  
Russell T. Joffe ◽  
Gerard P. Lippert ◽  
Trevor A. Gray ◽  
Gordon Sawa ◽  
Ziporah Horvath

1989 ◽  
Vol 155 (2) ◽  
pp. 220-224 ◽  
Author(s):  
Kit Stone

A retrospective study of 92 patients admitted with mania, aged over 65 years of age, found that 26% had no prior history of affective illness; 30% had previously only experienced depression, and half of these had at least three episodes of depression before the first manic illness. Patients with a family history of affective disorders had a significantly earlier age of onset of illness. There was evidence of cerebral organic impairment in 24% of the patients, and this group had a significantly later age of onset of illness. Prognosis was good, with only 8% still in hospital at six months. Half of the patients were started on lithium prophylaxis, but this did not significantly alter the number of readmissions. A quarter of those started on lithium developed evidence of lithium toxicity.


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