Constructing a hybrid molecule with low capacity of IgE binding from Chenopodium album pollen allergens

2012 ◽  
Vol 144 (1-2) ◽  
pp. 67-77 ◽  
Author(s):  
Hamid Reza Nouri ◽  
Abdolreza Varasteh ◽  
Fatemeh Vahedi ◽  
Jamshidkhan Chamani ◽  
Danial Afsharzadeh ◽  
...  
Keyword(s):  
Chenopodium Album ◽  
Hybrid Molecule ◽  
Pollen Allergens ◽  
Ige Binding

Homology of Two cDNAs Coding for Birch Pollen Allergens with Calmodulin: Protein-Bound Ca2+ Affects the IgE-Binding Capacity

1992 ◽  
Vol 99 (2-4) ◽  
pp. 380-381 ◽  
Author(s):  
Susanne Seiberler ◽  
Otto Scheiner ◽  
Dietrich Kraft ◽  
Rudolf Valenta
Keyword(s):  
Binding Capacity ◽  
Birch Pollen ◽  
Pollen Allergens ◽  
Ige Binding

IgE-binding capacity of recombinant timothy grass (Phleum pratense) pollen allergens

1994 ◽  
Vol 94 (1) ◽  
pp. 88-94 ◽  
Author(s):  
Sylvia Laffer ◽  
Susanne Vrtala ◽  
Michael Duchêne ◽  
Ronald van Ree ◽  
Dietrich Kraft ◽  
...  
Keyword(s):  
Binding Capacity ◽  
Phleum Pratense ◽  
Pollen Allergens ◽  
Timothy Grass ◽  
Ige Binding

Two-Dimensional IgE-Binding Spectrum of Japanese Cedar (Cryptomeria japonica) Pollen Allergens

2004 ◽  
Vol 133 (2) ◽  
pp. 125-135 ◽  
Author(s):  
Takashi Fujimura ◽  
Seiko Shigeta ◽  
Seiji Kawamoto ◽  
Tsunehiro Aki ◽  
Masanori Masubuchi ◽  
...  
Keyword(s):  
Cryptomeria Japonica ◽  
Japanese Cedar ◽  
Two Dimensional ◽  
Pollen Allergens ◽  
Ige Binding

Extraordinary stability of IgE-binding Parietaria pollen allergens in relation to chemically bound flavonoids

1996 ◽  
Vol 33 (17-18) ◽  
pp. 1287-1293 ◽  
Author(s):  
M.L.González Romano ◽  
M.T. Gallego ◽  
L. Berrens
Keyword(s):  
Pollen Allergens ◽  
Ige Binding

Modulation of IgE-Binding Properties of Tree Pollen Allergens by Site-Directed Mutagenesis

1996 ◽  
pp. 127-135 ◽  
Author(s):  
Fátima Ferreira ◽  
Angelika Rohlfs ◽  
Karin Hoffmann-Sommergruber ◽  
Siegfried Schenk ◽  
Christof Ebner ◽  
...  
Keyword(s):  
Site Directed Mutagenesis ◽  
Directed Mutagenesis ◽  
Tree Pollen ◽  
Pollen Allergens ◽  
Binding Properties ◽  
Ige Binding

The relationship of IGE receptor topography to signaling activity in RBL-2H3 mast cells

1991 ◽  
Vol 49 ◽  
pp. 236-237
Author(s):  
J.R. Pfeiffer ◽  
J.C. Seagrave ◽  
C. Wofsy ◽  
J.M. Oliver
Keyword(s):  
Mast Cells ◽  
Protein A ◽  
Scattered Electron ◽  
Ige Receptor ◽  
Receptor Complexes ◽  
Ige Binding ◽  
Electron Imaging ◽  
Small Clusters ◽  
Relationship Of ◽  
The Relationship

In RBL-2H3 rat leukemic mast cells, crosslinking IgE-receptor complexes with anti-IgE antibody leads to degranulation. Receptor crosslinking also stimulates the redistribution of receptors on the cell surface, a process that can be observed by labeling the anti-IgE with 15 nm protein A-gold particles as described in Stump et al. (1989), followed by back-scattered electron imaging (BEI) in the scanning electron microscope. We report that anti-IgE binding stimulates the redistribution of IgE-receptor complexes at 37“C from a dispersed topography (singlets and doublets; S/D) to distributions dominated sequentially by short chains, small clusters and large aggregates of crosslinked receptors. These patterns can be observed (Figure 1), quantified (Figure 2) and analyzed statistically. Cells incubated with 1 μg/ml anti-IgE, a concentration that stimulates maximum net secretion, redistribute receptors as far as chains and small clusters during a 15 min incubation period. At 3 and 10 μg/ml anti-IgE, net secretion is reduced and the majority of receptors redistribute rapidly into clusters and large aggregates.

Allergic Reactions to Food Proteins

2011 ◽  
Vol 81 (23) ◽  
pp. 173-180 ◽  
Author(s):  
Barbara K. Ballmer-Weber
Keyword(s):  
Food Allergies ◽  
Allergic Reactions ◽  
Allergenic Food ◽  
Processed Foods ◽  
Legal Regulations ◽  
Pollen Allergens ◽  
Curative Therapy ◽  
Novel Foods ◽  
Allergenic Proteins ◽  
Adolescents And Adults

Four to eight percent of the population are estimated to be food-allergic. Most food allergies in adolescents and adults are acquired on the basis of cross-reaction to pollen allergens. Theses allergens are ubiquitous in the plant kingdom. Therefore pollen-allergic patients might acquire a multitude of different plant food allergies, and even react to novel foods to which they have never previously been exposed. A curative therapy for food allergy does not yet exist. Food-allergic patients have to rely on strict avoidance diets, The widespread use of industrially processed foods poses a general problem for food-allergic patients. Although the most frequent allergens must be declared openly in the list of ingredients, involuntary contamination with allergy-provoking compounds can occur. The precautionary labelling “may contain” is sometimes applied even if the chance of contamination is very low; on the other hand, foods not declared to contain possible traces of allergenic components may actually contain relevant amounts of allergenic proteins. Switzerland is the only country in Europe with legal regulations on contamination by allergenic food; however, the allowance of 1 g/kg is too high to protect a relevant proportion of food-allergic individuals.

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