Safety assessment of a lyophilized biomass of Tetraselmis chuii (TetraSOD®) in a 90 day feeding study

2019 ◽  
Vol 133 ◽  
pp. 110810 ◽  
Author(s):  
L. Mantecón ◽  
R. Moyano ◽  
A.M. Cameán ◽  
A. Jos
2017 ◽  
Vol 65 (27) ◽  
pp. 5545-5560 ◽  
Author(s):  
Bonnie Hong ◽  
Yingzhou Du ◽  
Pushkor Mukerji ◽  
Jason M. Roper ◽  
Laura M. Appenzeller

1993 ◽  
Vol 12 (3) ◽  
pp. 237-242

Aldioxa is a heterocyclic organic compound used in cosmetic products as an astringent and skin conditioning agent. The oral LD50 for mice exceeds 23 mg/kg, and 8 g/kg for rats. All of the toxicologic parameters investigated in a 94-day subchronic feeding study in rats were similar in the test and the control group. No significant macroscopic adverse results were obtained in a three generation study in which rats were fed diets containing 10% Aldioxa. A suspension containing 25% Aldioxa was not a sensitizer when applied to the shaved backs of 3 male guinea pigs, nor when 10 animals were given intradermal injections of a 2% Aldioxa suspension on alternating days for a total of 10 applications and challenged after a 10-day nontreatment period. A hydrophilic unguent containing 4% Aldioxa was neither an irritant nor a sensitizer when evaluated on 200 human volunteers. The safety of Aldioxa has not been completely documented and substantiated. It cannot be concluded that this ingredient is safe for use in cosmetic products until the appropriate needed safety data cited in the report have been obtained and evaluated.


2014 ◽  
Vol 95 (9) ◽  
pp. 1911-1917 ◽  
Author(s):  
Oumèma Nouri-Ellouz ◽  
Najiba Zeghal ◽  
Saloua Makni ◽  
Fatma Makni-Ayadi ◽  
Mouhanad Trigui ◽  
...  

2017 ◽  
Vol 100 ◽  
pp. 34-41 ◽  
Author(s):  
Xin Chen ◽  
Ming-Qing Gao ◽  
Dong Liang ◽  
Songna Yin ◽  
Kezhen Yao ◽  
...  

Author(s):  
Soraya Karami ◽  
Mohammad R. Sabzalian ◽  
Layasadat Khorsandi ◽  
Mehdi Rahimmalek

2017 ◽  
Vol 85 ◽  
pp. 1-6 ◽  
Author(s):  
Guangqiu Qin ◽  
Pingjing Wen ◽  
Yanwu Wang ◽  
Lujuan Zhang ◽  
Huili Liang ◽  
...  

1996 ◽  
Vol 24 (1) ◽  
pp. 6-8
Author(s):  
Gilbert S. Stoewsand ◽  
Judy L. Anderson ◽  
Richard W. Robinson

Author(s):  
Nana Sun ◽  
Chunlai Liang ◽  
Qiannan Zhang ◽  
Xue Geng ◽  
Haibo Liu ◽  
...  

2008 ◽  
Vol 52 (3) ◽  
pp. 311-323 ◽  
Author(s):  
Bruce G. Hammond ◽  
Joan K. Lemen ◽  
Gulam Ahmed ◽  
Kathleen D. Miller ◽  
Jeannie Kirkpatrick ◽  
...  

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