scholarly journals Safety assessment of genetically modified milk containing human beta-defensin-3 on rats by a 90-day feeding study

2017 ◽  
Vol 100 ◽  
pp. 34-41 ◽  
Author(s):  
Xin Chen ◽  
Ming-Qing Gao ◽  
Dong Liang ◽  
Songna Yin ◽  
Kezhen Yao ◽  
...  
Keyword(s):  
Safety Assessment ◽  
Genetically Modified ◽  
Feeding Study

scholarly journals Safety Assessment of Food and Feed from GM Crops in Europe: Evaluating EFSA’s Alternative Framework for the Rat 90-day Feeding Study

2017 ◽  
Vol 65 (27) ◽  
pp. 5545-5560 ◽  
Author(s):  
Bonnie Hong ◽  
Yingzhou Du ◽  
Pushkor Mukerji ◽  
Jason M. Roper ◽  
Laura M. Appenzeller
Keyword(s):  
Safety Assessment ◽  
Gm Crops ◽  
Alternative Framework ◽  
Feeding Study ◽  
Food And Feed

Final Report on the Safety Assessment of Aldioxa

1993 ◽  
Vol 12 (3) ◽  
pp. 237-242
Keyword(s):  
Organic Compound ◽  
Guinea Pigs ◽  
Safety Assessment ◽  
Safety Data ◽  
Control Group ◽  
Final Report ◽  
Cosmetic Products ◽  
Feeding Study ◽  
Human Volunteers

Aldioxa is a heterocyclic organic compound used in cosmetic products as an astringent and skin conditioning agent. The oral LD50 for mice exceeds 23 mg/kg, and 8 g/kg for rats. All of the toxicologic parameters investigated in a 94-day subchronic feeding study in rats were similar in the test and the control group. No significant macroscopic adverse results were obtained in a three generation study in which rats were fed diets containing 10% Aldioxa. A suspension containing 25% Aldioxa was not a sensitizer when applied to the shaved backs of 3 male guinea pigs, nor when 10 animals were given intradermal injections of a 2% Aldioxa suspension on alternating days for a total of 10 applications and challenged after a 10-day nontreatment period. A hydrophilic unguent containing 4% Aldioxa was neither an irritant nor a sensitizer when evaluated on 200 human volunteers. The safety of Aldioxa has not been completely documented and substantiated. It cannot be concluded that this ingredient is safe for use in cosmetic products until the appropriate needed safety data cited in the report have been obtained and evaluated.

scholarly journals Safety Assessment of Genetically Modified Feed: Is There Any Difference From Food?

2019 ◽  
Vol 10 ◽  
Author(s):  
Paula A. Giraldo ◽  
Hiroshi Shinozuka ◽  
German C. Spangenberg ◽  
Noel O.I. Cogan ◽  
Kevin F. Smith
Keyword(s):  
Safety Assessment ◽  
Genetically Modified

Safety assessment of food derived from genetically modified crops

2020 ◽  
pp. 655-673
Author(s):  
Premendra D. Dwivedi ◽  
Mukul Das ◽  
Sandeep Kumar ◽  
Alok Kumar Verma
Keyword(s):  
Safety Assessment ◽  
Genetically Modified ◽  
Genetically Modified Crops

scholarly journals Safety Assessment of Rice Genetically Modified with Soybean Glycinin by Feeding Studies on Rats

2000 ◽  
Vol 64 (9) ◽  
pp. 1881-1886 ◽  
Author(s):  
Keiko MOMMA ◽  
Wataru HASHIMOTO ◽  
Hye-Jin YOON ◽  
Sachiko OZAWA ◽  
Yasuki FUKUDA ◽  
...  
Keyword(s):  
Safety Assessment ◽  
Genetically Modified
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