Ameliorative effect of salidroside from Rhodiola Rosea L. on the gut microbiota subject to furan-induced liver injury in a mouse model

2019 ◽  
Vol 125 ◽  
pp. 333-340 ◽  
Author(s):  
Yuan Yuan ◽  
Xuan Wu ◽  
Xu Zhang ◽  
Yilin Hong ◽  
Haiyang Yan
Keyword(s):  
Liver Injury ◽  
Mouse Model ◽  
Gut Microbiota ◽  
Rhodiola Rosea ◽  
Ameliorative Effect

Crosstalk between gut microbiota and host lipid metabolism in a mouse model of alcoholic liver injury by chronic baijiu or ethanol feeding

2022 ◽  
Author(s):  
Cheng Fang ◽  
Qingwu Zhou ◽  
Qingyang Liu ◽  
Wei Jia ◽  
Yan Xu
Keyword(s):  
Lipid Metabolism ◽  
Liver Injury ◽  
Mouse Model ◽  
Gut Microbiota ◽  
Alcoholic Beverage ◽  
Alcoholic Liver Injury ◽  
Ethanol Feeding

This study demonstrates that compounds in baijiu, a traditional Chinese alcoholic beverage, can attenuate the development of ethanol-induced liver injury by regulating the crosstalk between gut microbiota and host lipid metabolism.

scholarly journals Western Diet Changes Gut Microbiota and Ameliorates Liver Injury in a Mouse Model with Human‐Like Bile Acid Composition

2021 ◽  
Author(s):  
Junichi Iwamoto ◽  
Akira Honda ◽  
Teruo Miyazaki ◽  
Tadakuni Monma ◽  
Hajime Ueda ◽  
...  
Keyword(s):  
Bile Acid ◽  
Liver Injury ◽  
Mouse Model ◽  
Gut Microbiota ◽  
Acid Composition ◽  
Western Diet

scholarly journals The Impact of Rhodiola Rosea On Biomarkers of Diabetes, Inflammation, and Gut Microbiota in a Leptin Receptor-Knockout Mouse Model

2022 ◽  
Author(s):  
Mahtab Jafari ◽  
Jasmin Grace Juanson Arabit ◽  
Robert Courville ◽  
Dara Kiani ◽  
John M. Chaston ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Mouse Model ◽  
Gut Microbiota ◽  
Leptin Receptor ◽  
Insulin Response ◽  
Rhodiola Rosea ◽  
Root Extract ◽  
Receptor Knockout Mouse ◽  
The Impact

Abstract Type 2 diabetes is the most prevalent endocrine disease in the world, and recently the gut microbiota have become a potential target for its management. Recent studies have illustrated that this disease may predispose individuals to certain microbiome compositions, and treatments like metformin have been shown to change gut microbiota and their associated metabolic pathways. However, given the limitations and side effects associated with pharmaceuticals currently being used for therapy of diabetes, there is a significant need for alternative treatments. In this study, we investigated the effects of a root extract from Rhodiola rosea in a Leptin receptor knockout (db/db) mouse model of type 2 diabetes. Our previous work showed that Rhodiola rosea had anti-inflammatory and gut microbiome-modulating properties, while extending lifespan in several animal models. In this study, treatment with Rhodiola rosea improved the insulin response, and significantly decreased serum lipopolysaccharide and C-reactive protein levels. We hypothesize that these changes may in part reflect the modulation of the microbiota, resulting in improved gut barrier integrity and decreasing the translocation of inflammatory biomolecules into the bloodstream. These findings indicate that Rhodiola rosea is an attractive candidate for further research in the management of type 2 diabetes.

NorUDCA improves liver injury and glucose sensitivity in a mouse model of obesity and steatosis

2015 ◽  
Vol 53 (05) ◽  
Author(s):  
D Steinacher ◽  
T Claudel ◽  
T Stojakovic ◽  
M Trauner
Keyword(s):  
Liver Injury ◽  
Mouse Model ◽  
Glucose Sensitivity

Regulatory effect of volatile compounds in fermented alcoholic beverages on gut microbiota and serum metabolism in mouse model

2021 ◽  
Author(s):  
Mei Ji ◽  
Cheng Fang ◽  
Wei Jia ◽  
Hai Du ◽  
Yan Xu
Keyword(s):  
Risk Factor ◽  
Liver Disease ◽  
Mouse Model ◽  
Gut Microbiota ◽  
Volatile Compounds ◽  
Alcoholic Liver Disease ◽  
Alcoholic Beverages ◽  
Regulatory Effect ◽  
Main Risk Factor

Ethanol (EtOH) is the main risk factor for alcoholic liver disease. However, fermented alcoholic beverages contain not only ethanol but also various volatile compounds. Currently, effects of volatile compounds in...

Geniposide suppresses liver injury in a mouse model of DDC ‐induced sclerosing cholangitis

2021 ◽  
Author(s):  
Min Wen ◽  
Yubei Liu ◽  
Ruiying Chen ◽  
Ping He ◽  
Feihua Wu ◽  
...  
Keyword(s):  
Liver Injury ◽  
Mouse Model ◽  
Sclerosing Cholangitis

scholarly journals Effects of gut microbiota remodeling on the dysbiosis induced by high fat diet in a mouse model of Gulf war illness

Life Sciences ◽  
2021 ◽  
pp. 119675
Author(s):  
Mariana Angoa-Pérez ◽  
Branislava Zagorac ◽  
Dina M. Francescutti ◽  
Kevin R. Theis ◽  
Donald M. Kuhn
Keyword(s):  
Mouse Model ◽  
Gut Microbiota ◽  
High Fat Diet ◽  
Gulf War ◽  
High Fat ◽  
Gulf War Illness
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