Safety assessment of Syzygium aromaticum flower bud (clove) extract with respect to testicular function in mice

2008 ◽  
Vol 46 (10) ◽  
pp. 3333-3338 ◽  
Author(s):  
Raghav Kumar Mishra ◽  
Shio Kumar Singh
2020 ◽  
Vol 45 (4) ◽  
pp. 52-57
Author(s):  
K. M. Okukpe ◽  
A. O. Adeyina ◽  
O. I. Alli ◽  
B. H. Ajao ◽  
O. M. Odesanmi ◽  
...  

Syzygium aromaticum (Clove) is a small evergreen tree of the myrtle family known for its unopened reddish-brown flower bud with strong aromatic flavor that are used for culinary purpose and are believed to have aphrodisiac properties. The objective of the experiment was to assess the effect of clove extract on hormone profile of West African Dwarf (WAD) bucks. One hundred and fifty WAD bucks with average weights of 10kg were randomly assigned to five treatments with 30bucks per treatment in a completely randomized design. Treatment A (control) and B were subcutaneously administered 0.1mL/kg of normal saline solution and 0.1mL/kg sildenafil citrate, respectively. Treatments C, D and E were administered 0.1, 0.2, and 0.3mL/kg of clove extract, respectively. The result showed a significant increase in WBC while PCV decreased with corresponding increase in extract doses. The extracts also significantly cause a reduction in creatinine, alkaline phosphatase (ALP) and aspartate aminotransferase (AST) with a significant increase in serum urea and alanine aminotransferase (ALT). There were significant increase in serum testosterone and prolactin while follicle stimulating hormone and luteinizing hormone were reduced. It was therefore concluded that subcutaneous administration of syzygium aromaticum extract could enhance sexual function at low doses of 0.1mL/kg body weight of bucks with no observable tissue damage.


2021 ◽  
Vol 2 (2) ◽  
pp. 93-103
Author(s):  
Nathaniel Hiwandika ◽  
Susana Elya Sudrajat ◽  
Ika Rahayu

Cloves is one of the native Indonesian plants and is used in many aspects of life. Cloves are used in multiple industries and as detergents, soaps, perfumes, food seasonings, aromatherapy, etc. Cloves are mainly used for ingredients in kretek cigarettes in Indonesia. Various studies of cloves reported they have good pharmacological and therapeutic effects. The main compounds of clove extract are eugenol and β-caryophyllene, which are powerful antibacterial and antifungal agents. The clove ethanolic extract showed the activity to inhibit Gram positive and negative bacteria such as B. cereus, S. aureus, E. coli, P. aeruginosa, S. pneumoniae, S. aureus, S. epidermidis, A. hydrophila, K. pneumoniae, P. gingivalis, and P. mirabilis. Clove essential oil has shown the ability to inhibit the growth of V. inaequalis, C. albicans, C. glabrata, and C. tropicalis. Cloves extract can be used as an essential ingredient of various medicines. However, it requires further research and trials.


2014 ◽  
Vol 17 (9) ◽  
pp. 1003-1010 ◽  
Author(s):  
Zheng Tu ◽  
Tijuana Moss-Pierce ◽  
Paul Ford ◽  
T. Alan Jiang

2019 ◽  
Vol 33 (5) ◽  
pp. e4867 ◽  
Author(s):  
B. Ajitha ◽  
Y. Ashok Kumar Reddy ◽  
Yonghee Lee ◽  
Min Jun Kim ◽  
Chi Won Ahn

Sign in / Sign up

Export Citation Format

Share Document