Role of the tumour necrosis family ligand APRIL in solid tumour development: Retrospective studies in bladder, ovarian and head and neck carcinomas

2008 ◽  
Vol 44 (15) ◽  
pp. 2097-2100 ◽  
Author(s):  
P. Mhawech-Fauceglia ◽  
A. Allal ◽  
K. Odunsi ◽  
C. Andrews ◽  
F.R. Herrmann ◽  
...  
2010 ◽  
Vol 40 (7) ◽  
pp. 639-644 ◽  
Author(s):  
H. Daiko ◽  
K. Nagai ◽  
J. Yoshida ◽  
M. Nishimura ◽  
T. Hishida ◽  
...  

2014 ◽  
Vol 40 (1) ◽  
pp. 178-189 ◽  
Author(s):  
Jon Cacicedo ◽  
Arturo Navarro ◽  
Filippo Alongi ◽  
Alfonso Gómez de Iturriaga ◽  
Olga del Hoyo ◽  
...  

2005 ◽  
Vol 71 (1) ◽  
pp. 81-86 ◽  
Author(s):  
Antonio L.A. Pereira ◽  
Simone S.L. Veras ◽  
Éricka J.D. Silveira ◽  
Flávio R.G. Seabra ◽  
Leão Pereira Pinto ◽  
...  

2012 ◽  
Vol 25 (8) ◽  
pp. 1069-1078 ◽  
Author(s):  
Sofía T Menéndez ◽  
Juan P Rodrigo ◽  
Saúl Álvarez-Teijeiro ◽  
M Ángeles Villaronga ◽  
Eva Allonca ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-13 ◽  
Author(s):  
Georgia Levidou ◽  
Ioly Kotta-Loizou ◽  
Jason Tasoulas ◽  
Thomas Papadopoulos ◽  
Stamatios Theocharis

Background. Hu-antigen R (HuR) is a posttranscriptional regulator of several target mRNAs, implicated in carcinogenesis. This review aims to present the current evidence regarding the biological role and potential clinical significance of HuR in head and neck carcinomas. Methods. The existing literature concerning HuR expression and function in head and neck carcinomas is critically presented and summarised. Results. HuR is expressed in the majority of the examined samples, showing higher cytoplasmic levels in malignant or premalignant cases. Moreover, HuR modulates several genes implicated in biological processes important for malignant transformation, growth, and invasiveness. HuR seems to be an adverse prognosticator in patients with OSCCs, whereas a correlation with a more aggressive phenotype is reported in several types of carcinomas. Conclusions. A consistent role of HuR in the carcinogenesis and progression of head and neck carcinomas is suggested; nevertheless, further studies are warranted to expand the present information.


2014 ◽  
Vol 50 ◽  
pp. S68-S69
Author(s):  
E. Gunduz ◽  
O.F. Hatipoglu ◽  
K.O. Yaykasli ◽  
K. Erdogan ◽  
E.N. Cetin ◽  
...  

2012 ◽  
Vol 48 ◽  
pp. S191
Author(s):  
S. Alvarez-Teiieiro ◽  
S. Tirados Menendez ◽  
J.P. Rodrigo ◽  
M.A. Villaronga ◽  
E. Allonca ◽  
...  

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