Left Ventricular Mechanics in Asymptomatic Normotensive and Hypertensive Patients with Aortic Regurgitation

2011 ◽  
Vol 24 (4) ◽  
pp. 385-391 ◽  
Author(s):  
Vaida Mizariene ◽  
Silvija Bucyte ◽  
Diana Zaliaduonyte-Peksiene ◽  
Regina Jonkaitiene ◽  
Jolanta Vaskelyte ◽  
...  
Keyword(s):  
Aortic Regurgitation ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
Ventricular Mechanics ◽  
Left Ventricular Mechanics

THE INFLUENCE OF GENDER ON LEFT VENTRICULAR MECHANICS IN HYPERTENSIVE PATIENTS

2018 ◽  
Vol 36 (Supplement 1) ◽  
pp. e232
Author(s):  
M. Tadic ◽  
C. Cuspidi ◽  
V. Celic ◽  
B. Ivanovic ◽  
B. Pencic ◽  
...  
Keyword(s):  
Left Ventricular ◽  
Hypertensive Patients ◽  
Ventricular Mechanics ◽  
Left Ventricular Mechanics

scholarly journals Imaging Aortic Regurgitation: The Incremental Benefit of Speckle Tracking Echocardiography

2015 ◽  
Vol 9 (1) ◽  
pp. 96-98
Author(s):  
Pankaj Garg ◽  
Firas Yassin ◽  
Roman Leischik
Keyword(s):  
Aortic Regurgitation ◽  
Longitudinal Strain ◽  
Systolic Function ◽  
Imaging Modality ◽  
Left Ventricular ◽  
Septal Wall ◽  
Ventricular Mechanics ◽  
Global Strain ◽  
Left Ventricular Mechanics ◽  
Lv Systolic Function

Aortic regurgitation (AR) affects global left ventricular mechanics. However, limited literature is available on how it may affect regional longitudinal strain. We present a case where severe AR jet is thrashing the anterior-septal wall and reducing its overall longitudinal performance most likely secondary to increased wall shear stress in diastole. This new insight into patho-physiological process using deformation study may have supplementary impact in decision making for surgical intervention. Transthoracic echocardiography is the primary imaging modality for the assessment of AR as it offers evaluation of severity of AR, aetiology of AR, left ventricular (LV) dilatation, LV systolic function, left ventricular mass, diastolic function and global strain. This case highlights the regional disturbances in longitudinal strain in eccentric AR.

scholarly journals Association Between Left Ventricular Mechanics and Heart Rate Variability in Untreated Hypertensive Patients

2014 ◽  
Vol 17 (2) ◽  
pp. 118-125 ◽  
Author(s):  
Marijana Tadic ◽  
Cesare Cuspidi ◽  
Biljana Pencic ◽  
Sinisa U. Pavlovic ◽  
Branislava Ivanovic ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
Ventricular Mechanics ◽  
Left Ventricular Mechanics

scholarly journals Global longitudinal strain in chronic asymptomatic aortic regurgitation: systematic review

2020 ◽  
Vol 7 (3) ◽  
pp. 39-48
Author(s):  
Diana deCampos ◽  
Rogério Teixeira ◽  
Carolina Saleiro ◽  
Ana Botelho ◽  
Lino Gonçalves
Keyword(s):  
Systematic Review ◽  
Disease Progression ◽  
Aortic Regurgitation ◽  
Longitudinal Strain ◽  
Global Longitudinal Strain ◽  
Left Ventricular ◽  
Ventricular Mechanics ◽  
Left Ventricular Mechanics ◽  
Long Time ◽  
Chronic Aortic Regurgitation

Chronic aortic regurgitation (AR) patients typically remain asymptomatic for a long time. Left ventricular mechanics, namely global longitudinal strain (GLS), has been associated with outcomes in AR patients. The authors conducted a systematic review to summarize and appraise GLS impact on mortality, the need for aortic valve replacement (AVR) and disease progression in AR patients. A literature search was performed using these key terms ‘aortic regurgitation’ and ‘longitudinal strain’ looking at all randomized and nonrandomized studies conducted on chronic aortic regurgitation. The search yielded six observational studies published from 2011 and 2018 with a total of 1571 patients with moderate to severe chronic AR. Only two studies included all-cause mortality as their endpoint. The other studies looked at the association between GLS with AVR and disease progression. The mean follow-up period was 4.2 years. We noted a great variability of clinical, methodological and/or statistical origin. Thus, meta-analytic portion of our study was limited. Despite a relevant heterogeneity, an impaired GLS was associated with adverse cardiac outcomes. Left ventricular GLS may offer incremental value in risk stratification and decision-making.

scholarly journals Oxidative Stress State Is Associated with Left Ventricular Mechanics Changes, Measured by Speckle Tracking in Essential Hypertensive Patients

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Luis Antonio Moreno-Ruíz ◽  
David Ibarra-Quevedo ◽  
Erika Rodríguez-Martínez ◽  
Perla D. Maldonado ◽  
Benito Sarabia-Ortega ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Stress State ◽  
Diastolic Pressure ◽  
Global Longitudinal Strain ◽  
Left Ventricular ◽  
Sod Activity ◽  
Hypertensive Patients ◽  
Oxidized Proteins ◽  
Ventricular Mechanics ◽  
Left Ventricular Mechanics

The oxidative stress state is characterized by an increase in oxygen reactive species that overwhelms the antioxidant defense; we do not know if these pathological changes are correlated with alterations in left ventricular mechanics. The aim was correlating the oxidative stress state with the left ventricular global longitudinal strain (GLS) and the left ventricular end diastolic pressure (LVEDP). Twenty-five patients with essential hypertension and 25 controls paired by age and gender were studied. All of the participants were subjected to echocardiography and biochemical determination of oxidative stress markers. The hypertensive patients, compared with control subjects, had significantly (p<0.05) higher levels of oxidized proteins (5.03±1.05versus4.06±0.63 nmol/mg), lower levels of extracellular superoxide dismutase (EC-SOD) activity (0.045±0.02versus0.082±0.02 U/mg), higher LVEDP (16.2±4.5versus11.3±1.6 mm Hg), and lower GLS (−12% versus −16%). Both groups had preserved ejection fraction and the results showed a positive correlation of oxidized proteins with GLS (r=0.386,p=0.006) and LVEDP (r=0.389,p=0.005); we also found a negative correlation of EC-SOD activity with GLS (r=-0.404,p=0.004) and LVEDP (r=-0.347,p=0.014).

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