Genetic association of adiponectin gene polymorphisms (+45T/G and +10211T/G) with type 2 diabetes in North Indians

2012 ◽  
Vol 6 (2) ◽  
pp. 65-69 ◽  
Author(s):  
Madhukar Saxena ◽  
Neena Srivastava ◽  
Monisha Banerjee
Keyword(s):  
Type 2 Diabetes ◽  
Genetic Association ◽  
Gene Polymorphisms ◽  
Adiponectin Gene ◽  
North Indians

Adiponectin gene polymorphisms as a predictor for development of type 2 diabetes mellitus in Iraqi population

Gene ◽  
2018 ◽  
Vol 662 ◽  
pp. 118-122 ◽  
Author(s):  
Majid Kadhum Hussain ◽  
Falah Abdulhasan Deli ◽  
Abdul Hussein A. Algenabi ◽  
Khalid H. Abdul-Rudha
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Gene Polymorphisms ◽  
Adiponectin Gene

scholarly journals Association of Adiponectin Gene Polymorphisms With Type 2 Diabetes in an African American Population Enriched for Nephropathy

Diabetes ◽  
2008 ◽  
Vol 58 (2) ◽  
pp. 499-504 ◽  
Author(s):  
M. A. Bostrom ◽  
B. I. Freedman ◽  
C. D. Langefeld ◽  
L. Liu ◽  
P. J. Hicks ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
African American ◽  
Gene Polymorphisms ◽  
American Population ◽  
Adiponectin Gene ◽  
African American Population

Association of adiponectin gene polymorphisms and their haplotypes with type 2 diabetes and related metabolic traits in an Iranian population

2020 ◽  
Vol 40 (2) ◽  
pp. 216-222
Author(s):  
Hamid Reza Joshaghani ◽  
Parviz Kokhaei ◽  
Mehdi Barati ◽  
Abbas Pakdel ◽  
Ghorban Mohammadzadeh ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Gene Polymorphisms ◽  
Iranian Population ◽  
Adiponectin Gene ◽  
Metabolic Traits

scholarly journals Association between Adiponectin Gene Polymorphism and Environmental Risk Factors of Type 2 Diabetes Mellitus among the Chinese Population in Hohhot

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Meng Cui ◽  
Yumin Gao ◽  
Yanping Zhao ◽  
Hui Pang ◽  
Le Chen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Environmental Risk ◽  
Gene Polymorphisms ◽  
Central Obesity ◽  
Environmental Risk Factors ◽  
Adiponectin Gene

Objective. The aim of this study was to investigate the association between adiponectin gene polymorphisms rs10937273, rs1501299, rs182052, rs2241767, and rs266729 and environmental risk factors of type 2 diabetes mellitus (T2DM) in Hohhot. The study explored different models of gene-environment interactions, aimed at providing approaches for the prevention and control of T2DM in combination with the characteristics of the local population. Methods. A case-control study was conducted including 406 Chinese participants, comprising 203 cases and 203 controls from various hospitals. Adiponectin (ADIPOQ) gene polymorphisms rs10937273, rs1501299, rs182052, rs2241767, and rs266729 were detected using an improved multiple ligation detection reaction technique. Generalized multifactor dimensionality reduction (GMDR) and logistic regression were conducted to analyze the associations between adiponectin gene polymorphisms and T2DM, as well as the interactions between adiponectin gene polymorphisms and environmental factors. Results. ADIPOQ gene polymorphisms rs10937273, rs1501299, rs182052, rs2241767, and rs266729 were associated with type 2 diabetes. Based on the haplotype of the five adiponectin gene single-nucleotide polymorphism (SNP) loci, we found that G-G-A-A-C was a susceptible haplotype of T2DM (P<0.05). Interaction analyses demonstrated associations between rs1501299 and central obesity (consistency=80%, P=0.011) and between rs266729 and rs182052 and central obesity (consistency=70%, P=0.011). Conclusions. Our findings indicate that there is an interaction between the ADIPOQ gene and central obesity, which provides new insights into the prevention and treatment of T2DM.

scholarly journals Calpain-10 and Adiponectin Gene Polymorphisms in Korean Type 2 Diabetes Patients

2018 ◽  
Vol 33 (3) ◽  
pp. 364 ◽  
Author(s):  
Ji Sun Nam ◽  
Jung Woo Han ◽  
Sang Bae Lee ◽  
Ji Hong You ◽  
Min Jin Kim ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Gene Polymorphisms ◽  
Adiponectin Gene ◽  
Calpain 10 ◽  
Korean Type ◽  
Diabetes Patients
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