scholarly journals Single-Component Bismuth Nanoparticles as a Theranostic Agent for Multimodal Imaging-Guided Glioma Therapy

2019 ◽  
Vol 17 ◽  
pp. 619-627 ◽  
Author(s):  
Shu-Ting Lu ◽  
Dan Xu ◽  
Ru-Fang Liao ◽  
Jia-Zhen Luo ◽  
Yu-Hang Liu ◽  
...  
Keyword(s):  
Multimodal Imaging ◽  
Single Component ◽  
Bismuth Nanoparticles ◽  
Theranostic Agent

Ag2S nanoparticles as an emerging single-component theranostic agent

2020 ◽  
Vol 31 (7) ◽  
pp. 1717-1728 ◽  
Author(s):  
Ruxia Han ◽  
Jinrong Peng ◽  
Yao Xiao ◽  
Ying Hao ◽  
Yanpeng Jia ◽  
...  
Keyword(s):  
Single Component ◽  
Theranostic Agent ◽  
Ag2s Nanoparticles

Cobalt Phosphide Nanoparticles Applied as a Theranostic Agent for Multimodal Imaging and Anticancer Photothermal Therapy

2018 ◽  
Vol 35 (8) ◽  
pp. 1800127 ◽  
Author(s):  
Zhenglin Li ◽  
Shaoshan Hu ◽  
Jing Liu ◽  
Ying Hu ◽  
Lei Chen ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Multimodal Imaging ◽  
Cobalt Phosphide ◽  
Theranostic Agent

Multifunctional Bismuth Nanoparticles as Theranostic Agent for PA/CT Imaging and NIR Laser-Driven Photothermal Therapy

2018 ◽  
Vol 1 (2) ◽  
pp. 820-830 ◽  
Author(s):  
Chunyu Yang ◽  
Chongshen Guo ◽  
Wei Guo ◽  
Xiaole Zhao ◽  
Shaoqin Liu ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Ct Imaging ◽  
Bismuth Nanoparticles ◽  
Theranostic Agent ◽  
Nir Laser

Bioactive MOFs Based Theranostic Agent for Highly Effective Combination of Multimodal Imaging and Chemo‐Phototherapy

2020 ◽  
Vol 9 (14) ◽  
pp. 2000205 ◽  
Author(s):  
Yuda Zhu ◽  
Nini Xin ◽  
Zi Qiao ◽  
Suping Chen ◽  
Lingwan Zeng ◽  
...  
Keyword(s):  
Multimodal Imaging ◽  
Theranostic Agent ◽  
Effective Combination ◽  
Highly Effective

Polypyrrole-based double rare earth hybrid nanoparticles for multimodal imaging and photothermal therapy

2020 ◽  
Vol 8 (3) ◽  
pp. 426-437 ◽  
Author(s):  
Xueru Shan ◽  
Qian Chen ◽  
Xiangyu Yin ◽  
Chunzhu Jiang ◽  
Tinghua Li ◽  
...  
Keyword(s):  
Rare Earth ◽  
Cancer Therapy ◽  
Rare Earth Elements ◽  
Photothermal Therapy ◽  
Multimodal Imaging ◽  
Hybrid Nanoparticles ◽  
Theranostic Agent ◽  
Promising Application

A polypyrrole-based theranostic agent containing double rare-earth elements was constructed and demonstrated promising application for T1/T2-weighted MRI/CT tri-modal imaging guided photothermal cancer therapy.

scholarly journals Chlorotoxin—A Multimodal Imaging Platform for Targeting Glioma Tumors

Toxins ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 496 ◽  
Author(s):  
Gadi Cohen ◽  
Scott Burks ◽  
Joseph Frank
Keyword(s):  
Chloride Channels ◽  
Multimodal Imaging ◽  
Therapeutic Agents ◽  
Cross Reactivity ◽  
Matrix Metalloproteinase 2 ◽  
Normal Brain ◽  
Theranostic Agent ◽  
Neuroectodermal Tumors ◽  
Annexin 2 ◽  
Glioma Tumors

Chlorotoxin (CTX) is a 36-amino-acid disulfide-containing peptide derived from the venom of the scorpion Leiurus quinquestriatus. CTX alters physiology in numerous ways. It interacts with voltage gated chloride channels, Annexin-2, and matrix metalloproteinase-2 (MMP-2). CTX-based bioconjugates have been widely subjected to phase I/II clinical trials and have shown substantial promise. Many studies have demonstrated that CTX preferentially binds to neuroectodermal tumors, such as glioblastoma, without cross-reactivity to normal brain cells. With its ability to penetrate the blood-brain-barrier (BBB) and its tyrosine residue allows covalent conjugation with functional moieties, CTX is an attractive platform to explore development of diagnostic and therapeutic agents for gliomas. In this review, we outline CTX structure and its molecular targets, summarize molecular variations of CTX developed for glioma imaging, and discuss future trends and perspectives for CTX conjugates as a theranostic agent.

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