Sex differences in Indian patients with obsessive-compulsive disorder

2009 ◽  
Vol 50 (1) ◽  
pp. 70-75 ◽  
Author(s):  
T.S. Jaisoorya ◽  
Y.C. Janardhan Reddy ◽  
S. Srinath ◽  
K. Thennarasu
Keyword(s):  
Sex Differences ◽  
Obsessive Compulsive Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Indian Patients

scholarly journals Sex differences in the genetic architecture of obsessive-compulsive disorder

2018 ◽  
Vol 180 (6) ◽  
pp. 351-364 ◽  
Author(s):  
Ekaterina A. Khramtsova ◽  
Raphael Heldman ◽  
Eske M. Derks ◽  
Dongmei Yu ◽  
Lea K. Davis ◽  
...  
Keyword(s):  
Sex Differences ◽  
Obsessive Compulsive Disorder ◽  
Genetic Architecture ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

scholarly journals Predicting Eating Disorder and Anxiety Symptoms Using Anorexia Nervosa and Obsessive-Compulsive Disorder Polygenic Scores

2020 ◽  
Author(s):  
Zeynep Yilmaz ◽  
Katherine Schaumberg ◽  
Matt Halvorsen ◽  
Erica L. Goodman ◽  
Leigh C. Brosof ◽  
...  
Keyword(s):  
Eating Disorders ◽  
Sex Differences ◽  
Anorexia Nervosa ◽  
Eating Disorder ◽  
Obsessive Compulsive Disorder ◽  
Genetic Risk ◽  
Anxiety Symptoms ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Polygenic Scores

Clinical, epidemiological, and genetic findings support an overlap between eating disorders, obsessive-compulsive disorder (OCD), and anxiety symptoms. However, little research has examined the role of genetic factors in the expression of eating disorders and OCD/anxiety phenotypes. We examined whether the anorexia nervosa (AN), OCD, or AN/OCD transdiagnostic polygenic scores (PGS) predict eating disorders, OCD, and anxiety symptoms in a large population-based developmental cohort. Using summary statistics files from the Psychiatric Genomics Consortium Freeze 2 AN and Freeze 1 OCD GWAS, we first conducted an AN/OCD transdiagnostic GWAS meta-analysis and then calculated PGS for AN, OCD, and AN/OCD in participants from the Avon Longitudinal Study of Parents and Children with available genetic and phenotype data on eating disorder, OCD, and anxiety diagnoses and symptoms (sample size 3,212-5,369 per phenotype). We observed sex differences in the PGS prediction of eating disorder, OCD, and anxiety-related phenotypes, with AN genetic risk manifesting at an earlier age and playing a more prominent role in eating disorder phenotypes in boys than in girls. Compulsive exercise was the only phenotype predicted by all three PGS (e.g., PAN(boys)=0.0141 at age 14; POCD(girls)=0.0070 at age 16; PAN/OCD(all)=0.0297 at age 14). Our results suggest that earlier detection of eating disorder, OCD, and anxiety-related symptoms could be made possible by including measurement of genetic risk for these psychiatric conditions while being mindful of sex differences.

Are There Sex Differences in Neuropsychological Functions Among Patients With Obsessive-Compulsive Disorder?

2006 ◽  
Vol 13 (1) ◽  
pp. 42-50 ◽  
Author(s):  
David Mataix-Cols ◽  
Qazi Rahman ◽  
Mary Spiller ◽  
Maria Pino Alonso ◽  
Josep Pifarre ◽  
...  
Keyword(s):  
Sex Differences ◽  
Obsessive Compulsive Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Neuropsychological Functions

scholarly journals Suicidal behaviour of Indian patients with obsessive compulsive disorder

2013 ◽  
Vol 55 (2) ◽  
pp. 161 ◽  
Author(s):  
JitendraKumar Trivedi ◽  
Anil Nischal ◽  
PramodKumar Sinha ◽  
Subham Verma ◽  
Mohan Dhyani
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Suicidal Behaviour ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Indian Patients

Universal sex-specific instantiations of obsessive-compulsive disorder

2006 ◽  
Vol 29 (6) ◽  
pp. 629-629
Author(s):  
Gad Saad
Keyword(s):  
Sex Differences ◽  
Obsessive Compulsive Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Numerous sex differences in obsessive-compulsive disorder (OCD) instantiations are likely universal, as the associated evolutionary threats and concerns onto which they map were differentially important to the two sexes. Hence, although some ritualized behaviors or thoughts are indeed culture-specific, others are both culturally and temporally invariant as they are rooted in universal Darwinian etiologies (e.g., the sex differences in OCD symptomatology posited here).

Sex differences in the phenotypic expression of obsessive-compulsive disorder: an exploratory study from Brazil

2009 ◽  
Vol 50 (1) ◽  
pp. 63-69 ◽  
Author(s):  
Ricardo Cezar Torresan ◽  
Ana Teresa de Abreu Ramos-Cerqueira ◽  
Maria Alice de Mathis ◽  
Juliana Belo Diniz ◽  
Ygor Arzeno Ferrão ◽  
...  
Keyword(s):  
Sex Differences ◽  
Obsessive Compulsive Disorder ◽  
Exploratory Study ◽  
Phenotypic Expression ◽  
Obsessive Compulsive ◽  
Compulsive Disorder
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