Serum levels of glutathione peroxidase and superoxide dismutase in patients with chronic viral hepatitis

2019 ◽  
Vol 493 ◽  
pp. S365-S366
Author(s):  
D. Terziev ◽  
D. Terzieva ◽  
V. Andonov ◽  
N. Mateva
Keyword(s):  
Superoxide Dismutase ◽  
Glutathione Peroxidase ◽  
Viral Hepatitis ◽  
Serum Levels ◽  
Chronic Viral Hepatitis

Serum levels of soluble CD30 in chronic viral hepatitis and alcoholic liver disease (ALD)

1998 ◽  
Vol 114 ◽  
pp. A1327
Author(s):  
P. Ravagnan ◽  
U. Lorenzoni ◽  
E.A. Galliani ◽  
ML. Tenderini ◽  
A. Popovic' ◽  
...  
Keyword(s):  
Liver Disease ◽  
Viral Hepatitis ◽  
Alcoholic Liver Disease ◽  
Serum Levels ◽  
Chronic Viral Hepatitis ◽  
Soluble Cd30

COMP serum levels: A new non-invasive biomarker of liver fibrosis in patients with chronic viral hepatitis

2017 ◽  
Vol 38 ◽  
pp. 83-88 ◽  
Author(s):  
Kalliopi Zachou ◽  
Stella Gabeta ◽  
Zakera Shums ◽  
Nikolaos K. Gatselis ◽  
George K. Koukoulis ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Viral Hepatitis ◽  
Serum Levels ◽  
Chronic Viral Hepatitis ◽  
Non Invasive

Serum levels of soluble interleukin-2 receptors in acute and chronic viral hepatitis

1989 ◽  
Vol 34 (10) ◽  
pp. 1559-1563 ◽  
Author(s):  
Alfredo Alberti ◽  
Liliana Chemello ◽  
Giovanna Fattovich ◽  
Patrizia Pontisso ◽  
Giampietro Semenzato ◽  
...  
Keyword(s):  
Viral Hepatitis ◽  
Interleukin 2 ◽  
Serum Levels ◽  
Chronic Viral Hepatitis

scholarly journals Effects of Three Types of Massage on Serum Levels of Malondialdehyde, Superoxide Dismutase and Glutathione Peroxidase After One Session of Exhaustive Exercise in Female Futsal Players

2021 ◽  
Vol 10 (4) ◽  
pp. 328-339
Author(s):  
Bahare Heydari ◽  
◽  
Mohsen Ghofrani ◽  
Mohammad Ebrahim Bahram ◽  
◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Superoxide Dismutase ◽  
Glutathione Peroxidase ◽  
Recovery Period ◽  
Serum Levels ◽  
The Body ◽  
Exhaustive Exercise ◽  
Oxidative Stress Marker ◽  
Control Group ◽  
Significant Difference

Objective: The production of reactive oxygen species in exercise causes oxidative stress which disturbs the balance of oxidants and antioxidants, causing destructive effects on cells. The present study aims to investigate the effect of three types of massage (Swedish, Russian, Thai) on serum levels of Malondialdehyde (MDA), Glutathione Peroxidase (GPX) and Superoxide Dismutase (SOD) following one session of exhaustive exercise. Methods: This quasi-experimental study was conducted on 48 female futsal players aged 17-22 years in Zahedan, Iran who were selected using a purposive sampling method, and randomly divided into four groups of Swedish massage (Long strokes with pressing and tapping using hands), Russian massage (Medium to high pressure), Thai massage (Pressure to certain parts of the body) and Control. The exercise program was based on Bruce protocol. Serum levels of MDA, GPX and SOD were measured by before and immediately after exercise and after massage. Data analysis was performed using repeated measures ANOVA, considering a significance level of P≤0.05. Results: In all three types of massage, there was a significant decrease in serum level of MDA (0.22±0.08), and a significant increase in GPX (1.84±0.46) and SOD (10.02±2.86) levels after exhaustive (P=0.001). No significant difference was observed in the control group. Conclusion: It seems that Russian, Thai, and Swedish types of massage can affect the serum levels of the MDA (as an oxidative stress marker) and the antioxidant enzymes of GPX and SOD during the post-exercise recovery period.

scholarly journals Assessment of Serum Enzymatic Antioxidant Levels in Patients with Recurrent Aphthous Stomatitis: A Case Control Study

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Ishita Gupta ◽  
Arvind Shetti ◽  
Vaishali Keluskar ◽  
Anjana Bagewadi
Keyword(s):  
Superoxide Dismutase ◽  
Glutathione Peroxidase ◽  
Serum Levels ◽  
Recurrent Aphthous Stomatitis ◽  
The Body ◽  
Aphthous Stomatitis ◽  
Control Group ◽  
Study Group ◽  
Enzymatic Antioxidant ◽  
Exact Etiology

Background and Aim. Recurrent aphthous stomatitis (RAS) is a common oral mucosal disorder characterized by recurrent, painful oral aphthae. Despite extensive research, the exact etiology of RAS remains elusive. Recently oxidant-antioxidant imbalance of the body has been implicated in the pathogenesis of recurrent aphthous stomatitis. Thus, the aim of the study was to evaluate the enzymatic antioxidant levels in patients with recurrent aphthous stomatitis. Materials and Methods. The serum levels of superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) were measured in 30 patients with recurrent aphthous stomatitis and compared to the control group, which included 30 healthy subjects. Student’s t-test was performed for statistical evaluation. Results. The mean levels of superoxide dismutase (130.2 ± 15.94 U/mL) and glutathione peroxidase (3527.93 ± 488.32 U/L) were found to be significantly lower in study group as compared to control group (211.9 ± 20.93 U/mL, 8860.93 ± 1105.31 U/L, resp.) (P=0.000) while level of catalase in study group was significantly higher when compared to control group (10981.00 ± 1018.07 U/mL versus 9764.00 ± 1621.19 U/mL) (P=0.000). Conclusion. Enzymatic antioxidant system is impaired in recurrent aphthous stomatitis patients and seems to play a crucial role in its pathogenesis.

scholarly journals Functional significance of polymorphism of ApoE and SOD2 genes in formation of chronic HCV infection

2009 ◽  
Vol 8 (3) ◽  
pp. 64-68
Author(s):  
N. A. Semyonova ◽  
N. V. Ryazantseva ◽  
V. V. Novitsky ◽  
A. I. Dmitriyeva ◽  
O. Ye. Chechina ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Apolipoprotein E ◽  
Viral Hepatitis ◽  
Chronic Viral Hepatitis ◽  
Individual Level ◽  
Tomsk Region ◽  
Chronic Hcv Infection ◽  
Type C ◽  
Polymerase Chain ◽  
Chronic Hcv

The analysis of gene polymorphism plays an important role in assessment of disposition to infectious diseases at the population and individual level. In this paper, the frequencies of allelic versions of apolipoprotein E and 2nd type superoxide dismutase genes and the corresponding genotypes were determined in healthy persons and chronic viral hepatitis type C patients of the Europeoid population of the Tomsk Region. For the analysis of polymorphism of these genes, we used modern genetic methods: polymerase chain reaction and polymorphism of lengths of restriction fragments. For the studied population, it was revealed that the polymorphism of apolipoprotein E and 2nd type superoxide dismutase genes correlates with the development of chronic viral hepatitis type C and with the fibrogenesis process.

scholarly journals The role of serum bile acid profile in differentiation between nonalcoholic fatty liver disease and chronic viral hepatitis

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Azza Elsheashaey ◽  
Manar Obada ◽  
Eman Abdelsameea ◽  
Mohamed F. F. Bayomy ◽  
Hala El-Said
Keyword(s):  
Bile Acid ◽  
Viral Hepatitis ◽  
Bile Acids ◽  
Serum Levels ◽  
Chronic Viral Hepatitis ◽  
Serum Bile Acid ◽  
Nonalcoholic Fatty Liver ◽  
Bile Acid Level ◽  
The Mean

Abstract Background Bile acids are essential organic molecules synthesized from cholesterol in the liver. They have been utilized as indicators of hepatobiliary impairment because synthesis of BAs and their metabolism are influenced by liver diseases. We aimed to investigate the role of serum bile acid level and composition in differentiation between nonalcoholic fatty liver disease (NAFLD) and chronic viral hepatitis. An ultra-performance liquid chromatography coupled with mass spectrometry assay was used to measure the serum level of 14 bile acids in chronic viral hepatitis and NAFLD patients beside normal healthy control subjects. Results The mean serum levels of 11 out of the 14 bile acids (two primary, six conjugated, and three secondary) were significantly higher in viral hepatitis compared to control. Only 4 bile acids [2 primary, one glycine conjugated (GCDCA), and one secondary (LCA)] had statistically significant increase in their mean serum bile acid level in NAFLD compared to control. Comparing viral hepatitis group against NAFLD group revealed that the mean serum levels of five conjugated and one secondary bile acid (DCA) were significantly higher in viral hepatitis group. Receiver operating characteristic (ROC) curve analysis revealed that LCA had the best diagnostic performance for viral hepatitis followed by TCA and GCDCA. ROC curve for the combined three parameters had better sensitivity and specificity (70.55% and 94.87% respectively). Conclusion BA compositions including primary, secondary, and conjugated ones could differentiate between chronic viral hepatitis and NAFLD patients, and they might be potential distinguishing biomarkers for this purpose.

scholarly journals Laboratory Indicators of Aggrecan Turnover in Juvenile Idiopathic Arthritis

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Katarzyna Winsz-Szczotka ◽  
Kornelia Kuźnik-Trocha ◽  
Katarzyna Komosińska-Vassev ◽  
Agnieszka Jura-Półtorak ◽  
Krystyna Olczyk
Keyword(s):  
Superoxide Dismutase ◽  
Juvenile Idiopathic Arthritis ◽  
Serum Level ◽  
Glutathione Peroxidase ◽  
Chondroitin Sulfate ◽  
Serum Levels ◽  
Biochemical Changes ◽  
Early Marker ◽  
Before And After ◽  
Anti Inflammatory

Objectives. Evaluation of chondroitin sulfate (CS), as an early marker of aggrecan degradation, and chondroitin sulfate 846 epitope (CS846), as a biomarker of CS synthesis, is an attempt at answering the question whether the therapy used in juvenile idiopathic arthritis (JIA) patients contributes to the normalization of biochemical changes in aggrecan.Methods and Results. Serum levels of CS and CS846 as well as catalase (CT), superoxide dismutase (SOD), and glutathione peroxidase (GPx) activities in erythrocyte were assessed in patients before and after treatment. In the course of JIA, aggrecan metabolism is disturbed, which is reflected by a decrease (p<0.001) in CS serum level and an increase (p<0.05) in CS846 concentration. Furthermore, increased (p<0.001) activities of CT, SOD, and GPx in untreated JIA patients were recorded. The anti-inflammatory treatment resulted in the normalization of CS846 level and SOD and GPx activities. In untreated patients, we have revealed a significant correlation between serum CS and CS846, CT, CRP, ESR, MMP-3, and ADAMTS-4, respectively, as well as between CS846 and CT, GPx, CRP, ESR, and TGF-β1, respectively.Conclusion. The observed changes of CS and CS846 in JIA patients indicate a further need of the therapy continuation aimed at protecting a patient from a possible disability.

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