A nationwide survey of bilirubin encephalopathy in preterm infants in Japan

2020 ◽  
Vol 42 (10) ◽  
pp. 730-737
Author(s):  
Akihisa Okumura ◽  
Ichiro Morioka ◽  
Hiroshi Arai ◽  
Masahiro Hayakawa ◽  
Yoshihiro Maruo ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Nationwide Survey ◽  
Bilirubin Encephalopathy

Neonatal Jaundice in Preterm Infants with Bilirubin Encephalopathy

Neonatology ◽  
2021 ◽  
pp. 1-9
Author(s):  
Akihisa Okumura ◽  
Shintaro Ichimura ◽  
Masahiro Hayakawa ◽  
Hiroshi Arai ◽  
Yoshihiro Maruo ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Total Bilirubin ◽  
Nationwide Survey ◽  
Albumin Level ◽  
Molar Ratio ◽  
Serum Total Bilirubin ◽  
Additional Information ◽  
Bilirubin Encephalopathy ◽  
Unbound Bilirubin ◽  
G Ratio

Introduction: The aim of this study is to clarify bilirubin parameters and its treatment in preterm infants with bilirubin encephalopathy (pBE). Methods: We asked the responders to an earlier nationwide Japanese survey on pBE to provide additional information. pBE was diagnosed based on the criteria used in the nationwide survey. We collected data on serum total bilirubin (TB), direct bilirubin (DB), albumin, and unbound bilirubin (UB) levels during the first 8 weeks of life, and on phototherapy and exchange transfusion treatments. Results: We obtained clinical data from 75 patients with pBE from 58 hospitals (response rate of 59%), who were born between 2002 and 2016. The average peak TB level was 12.6 mg/dL (215 μmol/L), and the average age at peak attainment was 19.7 days after birth. Albumin level was <2.5 g/dL in 44 patients, and the peak DB level was ≥2 mg/dL (34.2 μmol/L) in 20 patients. The average peak bilirubin/albumin (B/A) (mg/g) ratio was 3.8 (molar ratio of 0.475), and the average age at peak attainment was 18.6 days. The average peak UB level was 0.67 μg/dL (11.5 nmol/L). The median duration of phototherapy was 6 days, and the median day of the last session was 12. The peak TB level occurred after the last day of phototherapy in 30 of the 61 patients available for comparison. Conclusions: Most patients with pBE lacked marked elevations in serum TB levels and the B/A ratio, the peaks of which were sometimes delayed to >4 weeks after birth.

Diagnosis of Bilirubin Encephalopathy in Preterm Infants with Dyskinetic Cerebral Palsy

Neonatology ◽  
2019 ◽  
Vol 117 (1) ◽  
pp. 73-79 ◽  
Author(s):  
Yukihiro Kitai ◽  
Satori Hirai ◽  
Naomi Okuyama ◽  
Mika Hirotsune ◽  
Satoshi Mizutani ◽  
...  
Keyword(s):  
Cerebral Palsy ◽  
Preterm Infants ◽  
Bilirubin Encephalopathy

scholarly journals Biliary Atresia in Preterm Infants in Taiwan: A Nationwide Survey

2013 ◽  
Vol 163 (1) ◽  
pp. 100-103.e1 ◽  
Author(s):  
Chih-Yu Chiu ◽  
Po-Hon Chen ◽  
Chan-Fai Chan ◽  
Mei-Hwei Chang ◽  
Tzee-Chung Wu
Keyword(s):  
Biliary Atresia ◽  
Preterm Infants ◽  
Nationwide Survey

MRI Findings in Preterm Infants with Bilirubin Encephalopathy beyond 3 Years of Corrected Age

2021 ◽  
Author(s):  
Akihisa Okumura ◽  
Yukihiro Kitai ◽  
Hiroshi Arai ◽  
Masahiro Hayakawa ◽  
Yoshihiro Maruo ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Mri Findings ◽  
Bilirubin Encephalopathy

Auditory brainstem response in preterm infants with bilirubin encephalopathy

2021 ◽  
Vol 154 ◽  
pp. 105319
Author(s):  
Akihisa Okumura ◽  
Yukihiro Kitai ◽  
Hiroshi Arai ◽  
Masahiro Hayakawa ◽  
Yoshihiro Maruo ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Auditory Brainstem Response ◽  
Auditory Brainstem ◽  
Bilirubin Encephalopathy ◽  
Brainstem Response

Proton Magnetic Resonance Spectroscopic Images in Preterm Infants with Bilirubin Encephalopathy

2012 ◽  
Vol 160 (2) ◽  
pp. 342-344 ◽  
Author(s):  
Atsushi Kamei ◽  
Makoto Sasaki ◽  
Manami Akasaka ◽  
Nami Soga ◽  
Kohsuke Kudo ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Preterm Infants ◽  
Proton Magnetic Resonance ◽  
Bilirubin Encephalopathy

Auditory Arousal in Preterm Infants

1984 ◽  
Vol 11 ◽  
pp. 3-9 ◽  
Author(s):  
Kay Lynn Copriviza ◽  
Cynthia Gayle Lima
Keyword(s):  
Preterm Infants

Spinal anaesthesia and meningitis in former preterm infants: cause-effect?

1999 ◽  
Vol 9 (3) ◽  
pp. 262-264 ◽  
Author(s):  
G Luz ◽  
H Buchele ◽  
P Innerhofer ◽  
H Maurer
Keyword(s):  
Preterm Infants ◽  
Spinal Anaesthesia
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