scholarly journals Effects of vitamin D supplementation on bone turnover markers and other bone-related substances in subjects with vitamin D deficiency

Bone ◽  
2019 ◽  
Vol 124 ◽  
pp. 7-13 ◽  
Author(s):  
Rolf Jorde ◽  
Astrid Kamilla Stunes ◽  
Julia Kubiak ◽  
Ragnar Joakimsen ◽  
Guri Grimnes ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Turnover ◽  
Vitamin D Deficiency ◽  
Bone Turnover Markers ◽  
Vitamin D Supplementation ◽  
Related Substances ◽  
Turnover Markers

CIRCULATING BONE TURNOVER MARKERS AND THEIR RELATIONSHIPS IN HEMODIALYSIS PATIENTS WITH VITAMIN D DEFICIENCY

2019 ◽  
Vol 72 (11) ◽  
Author(s):  
Paweł Kulicki ◽  
Paweł Żebrowski ◽  
Antoni Sokalski ◽  
Wiesław Klatko ◽  
Magdalena Birecka ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Turnover ◽  
Vitamin D Deficiency ◽  
Bone Turnover Markers ◽  
Hemodialysis Patients ◽  
Turnover Markers

scholarly journals Effects of Vitamin D Supplementation on Bone Turnover Markers: A Randomized Controlled Trial

Nutrients ◽  
2017 ◽  
Vol 9 (5) ◽  
pp. 432 ◽  
Author(s):  
Verena Schwetz ◽  
Christian Trummer ◽  
Marlene Pandis ◽  
Martin Grübler ◽  
Nicolas Verheyen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Randomized Controlled Trial ◽  
Bone Turnover ◽  
Bone Turnover Markers ◽  
Controlled Trial ◽  
Vitamin D Supplementation ◽  
Randomized Controlled ◽  
Turnover Markers

scholarly journals The Effects of Season-Long Vitamin D Supplementation on Collegiate Swimmers and Divers

2013 ◽  
Vol 23 (5) ◽  
pp. 431-440 ◽  
Author(s):  
Regina M. Lewis ◽  
Maja Redzic ◽  
D. Travis Thomas
Keyword(s):  
Vitamin D ◽  
Body Composition ◽  
Bone Turnover ◽  
Inflammatory Cytokines ◽  
Bone Turnover Markers ◽  
Female Athletes ◽  
Vitamin D Supplementation ◽  
Mineral Density ◽  
Turnover Markers ◽  
Total Body

The purpose of this 6-month randomized, placebo-controlled trial was to determine the effect of season-long (September–March) vitamin D supplementation on changes in vitamin D status, which is measured as 25(OH) D, body composition, inflammation, and frequency of illness and injury. Forty-five male and female athletes were randomized to 4,000 IU vitamin D (n = 23) or placebo (n = 22). Bone turnover markers (NTx and BSAP), 25(OH)D, and inflammatory cytokines (TNF-alpha, IL-6, and IL1-β) were measured at baseline, midpoint, and endpoint. Body composition was assessed by DXA and injury and illness data were collected. All athletes had sufficient 25(OH)D (> 32 ng/ml) at baseline (mean: 57 ng/ml). At midpoint and endpoint, 13% and 16% of the total sample had 25(OH)D < 32 ng/ml, respectively. 25(OH)D was not positively correlated with bone mineral density (BMD) in the total body, proximal dual femur, or lumbar spine. In men, total body (p = .04) and trunk (p = .04) mineral-free lean mass (MFL) were positively correlated with 25(OH)D. In women, right femoral neck BMD (p = .02) was positively correlated with 25(OH)D. 25(OH)D did not correlate with changes in bone turnover markers or inflammatory cytokines. Illness (n = 1) and injury (n = 13) were not related to 25(OH)D; however, 77% of injuries coincided with decreases in 25(OH)D. Our data suggests that 4,000 IU vitamin D supplementation is an inexpensive intervention that effectively increased 25(OH)D, which was positively correlated to bone measures in the proximal dual femur and MFL. Future studies with larger sample sizes and improved supplement compliance are needed to expand our understanding of the effects of vitamin D supplementation in athletes.

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