CIRCULATING BONE TURNOVER MARKERS AND THEIR RELATIONSHIPS IN HEMODIALYSIS PATIENTS WITH VITAMIN D DEFICIENCY

2019 ◽  
Vol 72 (11) ◽  
Author(s):  
Paweł Kulicki ◽  
Paweł Żebrowski ◽  
Antoni Sokalski ◽  
Wiesław Klatko ◽  
Magdalena Birecka ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Turnover ◽  
Vitamin D Deficiency ◽  
Bone Turnover Markers ◽  
Hemodialysis Patients ◽  
Turnover Markers

scholarly journals Effects of vitamin D supplementation on bone turnover markers and other bone-related substances in subjects with vitamin D deficiency

Bone ◽  
2019 ◽  
Vol 124 ◽  
pp. 7-13 ◽  
Author(s):  
Rolf Jorde ◽  
Astrid Kamilla Stunes ◽  
Julia Kubiak ◽  
Ragnar Joakimsen ◽  
Guri Grimnes ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Turnover ◽  
Vitamin D Deficiency ◽  
Bone Turnover Markers ◽  
Vitamin D Supplementation ◽  
Related Substances ◽  
Turnover Markers

scholarly journals Serum levels of bone formation and resorption markers in relation to vitamin D status in professional gymnastics and physically active men during upper and lower body high-intensity exercise

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Jan Mieszkowski ◽  
Andrzej Kochanowicz ◽  
Elżbieta Piskorska ◽  
Bartłomiej Niespodziński ◽  
Joanna Siódmiak ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Formation ◽  
Bone Turnover ◽  
Bone Turnover Markers ◽  
Type I Collagen ◽  
Serum Levels ◽  
Type I ◽  
Vitamin D Metabolites ◽  
Physically Active ◽  
Turnover Markers

Abstract Purpose/introduction To compare serum levels of bone turnover markers in athletes and non-athletes, and to evaluate the relationship between serum levels of vitamin D metabolites and exercise-induced changes in biomarker levels. Methods Sixteen elite male artistic gymnasts (EG; 21.4 ± 0.8 years-old) and 16 physically active men (the control group, PAM; 20.9 ± 1.2 years-old) performed lower and upper body 30-s Wingate anaerobic tests (LBWT and UBWT, respectively). For biomarker analysis, blood samples were collected before, and 5 and 30 min after exercise. Samples for vitamin D levels were collected before exercise. N-terminal propeptide of type I collagen (PINP) was analysed as a marker of bone formation. C-terminal telopeptide of type I collagen (CTX) was analysed as a marker of bone resorption. Results UBWT fitness readings were better in the EG group than in the PAM group, with no difference in LBWT readings between the groups. UBWT mean power was 8.8% higher in subjects with 25(OH)D3 levels over 22.50 ng/ml and in those with 24,25(OH)2D3 levels over 1.27 ng/ml. Serum CTX levels increased after both tests in the PAM group, with no change in the EG group. PINP levels did not change in either group; however, in PAM subjects with 25(OH)D3 levels above the median, they were higher than those in EG subjects. Conclusion Vitamin D metabolites affect the anaerobic performance and bone turnover markers at rest and after exercise. Further, adaptation to physical activity modulates the effect of anaerobic exercise on bone metabolism markers.

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