scholarly journals Recent advances of electrochemical and optical enzyme-free glucose sensors operating at physiological conditions

2020 ◽  
Vol 165 ◽  
pp. 112331 ◽  
Author(s):  
Muhammad Adeel ◽  
Md. Mahbubur Rahman ◽  
Isabella Caligiuri ◽  
Vincenzo Canzonieri ◽  
Flavio Rizzolio ◽  
...  
Keyword(s):  
Glucose Sensors ◽  
Physiological Conditions ◽  
Recent Advances ◽  
Free Glucose

scholarly journals Recent Advances in Enzymatic and Non-Enzymatic Electrochemical Glucose Sensing

Sensors ◽  
2021 ◽  
Vol 21 (14) ◽  
pp. 4672
Author(s):  
Mohamed H. Hassan ◽  
Cian Vyas ◽  
Bruce Grieve ◽  
Paulo Bartolo
Keyword(s):  
Noble Metals ◽  
Direct Electrochemistry ◽  
Glucose Sensing ◽  
Glucose Sensors ◽  
Diabetic Patients ◽  
Past Century ◽  
Industrial Sectors ◽  
Recent Advances ◽  
Wide Range ◽  
Sensitivity And Selectivity

The detection of glucose is crucial in the management of diabetes and other medical conditions but also crucial in a wide range of industries such as food and beverages. The development of glucose sensors in the past century has allowed diabetic patients to effectively manage their disease and has saved lives. First-generation glucose sensors have considerable limitations in sensitivity and selectivity which has spurred the development of more advanced approaches for both the medical and industrial sectors. The wide range of application areas has resulted in a range of materials and fabrication techniques to produce novel glucose sensors that have higher sensitivity and selectivity, lower cost, and are simpler to use. A major focus has been on the development of enzymatic electrochemical sensors, typically using glucose oxidase. However, non-enzymatic approaches using direct electrochemistry of glucose on noble metals are now a viable approach in glucose biosensor design. This review discusses the mechanisms of electrochemical glucose sensing with a focus on the different generations of enzymatic-based sensors, their recent advances, and provides an overview of the next generation of non-enzymatic sensors. Advancements in manufacturing techniques and materials are key in propelling the field of glucose sensing, however, significant limitations remain which are highlighted in this review and requires addressing to obtain a more stable, sensitive, selective, cost efficient, and real-time glucose sensor.

scholarly journals Recent advancements, key challenges and solutions in non-enzymatic electrochemical glucose sensors based on graphene platforms

RSC Advances ◽  
2017 ◽  
Vol 7 (59) ◽  
pp. 36949-36976 ◽  
Author(s):  
G. Gnana kumar ◽  
G. Amala ◽  
S. M. Gowtham
Keyword(s):  
Glucose Sensors ◽  
Recent Advances

This review elucidates the recent advances in graphene platforms in electrochemical non-enzymatic glucose sensors and provides solutions for existing bottlenecks.

Nanosheets-assembled hierarchical microstructured Ni(OH)2 hollow spheres for highly sensitive enzyme-free glucose sensors

2015 ◽  
Vol 168 ◽  
pp. 148-156 ◽  
Author(s):  
Pan Lu ◽  
Qibin Liu ◽  
Yuzhu Xiong ◽  
Qing Wang ◽  
Yuting Lei ◽  
...  
Keyword(s):  
Hollow Spheres ◽  
Glucose Sensors ◽  
Highly Sensitive ◽  
Free Glucose

scholarly journals Optical glucose sensors based on hexagonally-packed 2.5-dimensional photonic concavities imprinted in phenylboronic acid functionalized hydrogel films

RSC Advances ◽  
2017 ◽  
Vol 7 (85) ◽  
pp. 53916-53924 ◽  
Author(s):  
Magdalena Bajgrowicz-Cieslak ◽  
Yousef Alqurashi ◽  
Mohamed Ismail Elshereif ◽  
Ali K. Yetisen ◽  
Muhammad Umair Hassan ◽  
...  
Keyword(s):  
Phenylboronic Acid ◽  
Glucose Sensors ◽  
Physiological Conditions ◽  
Glucose Levels ◽  
Hydrogel Films

A glucose-responsive hydrogel that changes its volume when exposed to different glucose concentrations was used to measure the glucose levels under physiological conditions.

Affinity Viscosimetry Sensor for Enzyme Free Detection of Glucose in a Micro-Bioreaction Chamber

2016 ◽  
Vol 879 ◽  
pp. 1135-1140
Author(s):  
Thilo Liebscher ◽  
Franziska Glös ◽  
Andrea Böhme ◽  
M. Birkholz ◽  
M. di Vona ◽  
...  
Keyword(s):  
Glucose Concentration ◽  
Glucose Sensor ◽  
Time Measurement ◽  
Glucose Sensors ◽  
Cell Cultivation ◽  
New Approach ◽  
Microelectromechanical System ◽  
Long Time ◽  
Free Glucose

With the growing demand of miniaturization of cell cultivation a new approach towards measuring and sensing bio-analytes needs to be made due to the problem of small volumes (less than 150μl) containing small amounts of analytes. Most of the available glucose sensors monitor the glucose concentration with the help of enzymes, which become very inaccurate in terms of long time measurement and uses (i.e. consumes) glucose during the measurement becoming not available anymore for the cells. Therefore, we focused on applying an enzyme-free glucose sensor based on a microelectromechanical system (MEMS).

scholarly journals Non-enzymatic glucose sensor with electrodeposited silver/carbon nanotubes composite electrode

2019 ◽  
Vol 39 (6) ◽  
Author(s):  
Syeda Ammara Shabbir ◽  
Sana Tariq ◽  
M. Gul Bahar Ashiq ◽  
Waqar A. Khan
Keyword(s):  
Carbon Nanotubes ◽  
Tin Oxide ◽  
Composite Electrode ◽  
Reduction Potential ◽  
Glucose Sensor ◽  
Electrochemical Process ◽  
Glucose Sensors ◽  
Functionalized Carbon Nanotubes ◽  
Good Electrocatalytic Activity ◽  
Free Glucose

Abstract Diabetes mellitus is a debilitating disease that affects each and every organ of human body. Hence it is important to continuously monitor the glucose level throughout the day and night. Glucose sensors are in great demand due to a rapid increase in diabetic community. A strategy has been implemented here to fabricate silver nanoparticles (AgNPs) with the support of functionalized carbon nanotubes (f-CNTs). Silver/carbon nanotubes (Ag/CNTs) nanocomposite electrode have been prepared by electrochemical process on Fluorine doped tin oxide (FTO) glass, by varying silver (Ag) concentrations for non-enzymatic glucose sensor. The variable Ag concentration in the morphology of Ag/CNTs nanocomposite has influenced the electrical conductivity, oxidation and reduction potential and electrochemical activity of glucose. Highest current density and good electrocatalytic activity for electrodes are obtained at 70 mM concentration of silver in Ag/CNTs composite. The present study indicates that the Ag/CNTs electrode is a possible substitute of the expensive glassy carbon electrode for enzyme-free glucose sensors.

scholarly journals Electrochemical non-enzymatic glucose sensors: recent progress and perspectives

2020 ◽  
Vol 56 (93) ◽  
pp. 14553-14569
Author(s):  
Ming Wei ◽  
Yanxia Qiao ◽  
Haitao Zhao ◽  
Jie Liang ◽  
Tingshuai Li ◽  
...  
Keyword(s):  
Influencing Factors ◽  
Recent Progress ◽  
Glucose Sensors ◽  
Glucose Detection ◽  
Sensing Mechanism ◽  
Recent Advances

This review summarizes recent advances in the development of electrocatalysts for non-enzymatic glucose detection. The sensing mechanism and influencing factors are discussed, and the perspectives and challenges are also addressed.

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