Abstract # 1726 Effects of tumor development and social stress on inflammation: Behavioral and physiological changes

2016 ◽  
Vol 57 ◽  
pp. e6
Author(s):  
A. Lebeña ◽  
A. Azpiroz ◽  
G. Beitia ◽  
E. Gómez-Lázaro ◽  
A. Arregi ◽  
...  
Keyword(s):  
Social Stress ◽  
Tumor Development ◽  
Physiological Changes

# 138 Social stress and coping strategies in male mice: Effects on tumor development

2005 ◽  
Vol 19 (4) ◽  
pp. e71
Author(s):  
Oscar Vegas ◽  
Eduardo Fano ◽  
Paul Fredric Brain ◽  
Ana Alonso ◽  
Arantza Azpiroz
Keyword(s):  
Coping Strategies ◽  
Social Stress ◽  
Tumor Development ◽  
Stress And Coping ◽  
Male Mice ◽  
And Coping

Hypertension as a Disease of Modern Society

1975 ◽  
Vol 5 (4) ◽  
pp. 539-558 ◽  
Author(s):  
Joseph Eyer
Keyword(s):  
Blood Pressure ◽  
Social Stress ◽  
Modern Society ◽  
Physiological Effects ◽  
Physiological Changes ◽  
Elevated Blood ◽  
Hunter Gatherers ◽  
Salt Consumption ◽  
Work Pressure ◽  
The Difference

About 50 per cent of people in modem societies have blood pressure sufficiently elevated to result in increased mortality. This proportion is much smaller in undisrupted societies of hunter-gatherers. In most cases the elevated blood pressure in modern societies is associated with physiological changes characteristic of chronic stress. The difference between blood pressure in modern populations and that in undisrupted hunter-gatherer societies cannot be accounted for by genetic differences or differences in salt consumption. Two primary features of modern society which contribute to the elevation of blood pressure are community disruption and increased work pressure. Drug therapy and relaxation therapies for hypertension attempt to counteract the physiological effects of social stress. However, it is more appropriate to use the occurrence of hypertension as an indicator of fundamental social problems which need to be solved.

Behavioral coping strategies predict tumor development and behavioral impairment after chronic social stress in mice

2020 ◽  
Vol 214 ◽  
pp. 112747
Author(s):  
Olatz Goñi-Balentziaga ◽  
Larraitz Garmendia ◽  
Ainitze Labaka ◽  
Andrea Lebeña ◽  
Garikoitz Beitia ◽  
...  
Keyword(s):  
Coping Strategies ◽  
Social Stress ◽  
Tumor Development ◽  
Behavioral Impairment ◽  
Chronic Social Stress

Altered thymic epithelial cells may be decisive for Moloney virus-induced lymphoma development

1983 ◽  
Vol 41 ◽  
pp. 784-785
Author(s):  
U.I. Heine ◽  
G.R.F. Krueger ◽  
E. Munoz ◽  
A. Karpinski
Keyword(s):  
Epithelial Cells ◽  
Leukemia Virus ◽  
Light And Electron Microscopy ◽  
Tumor Development ◽  
Current Evidence ◽  
Thymic Epithelial Cells ◽  
Thymic Tissue ◽  
Newborn Mice ◽  
Moloney Leukemia Virus ◽  
Differentiation Block

Infection of newborn mice with Moloney leukemia virus (M-MuLV) causes a T-cell differentiation block in the thymic cortex accompanied by proliferation and accumulation of prethymic lymphoblasts in the thymus and subsequent spreading of these cells to generate systemic lymphoma. Current evidence shows that thymic reticular epithelial cells (REC) provide a microenvironment necessary for the maturation of prethymic lymphoblasts to mature T-lymphocytes by secretion of various thymic factors. A change in that environment due to infection of REC by virus could be decisive for the failure of lymphoblasts to mature and thus contribute to lymphoma development.We have studied the morphology and distribution of the major thymic cell populations at different stages of tumorigenesis in Balb/c mice infected when newborn with 0.2ml M-MuLV suspension, 6.8 log FFU/ml. Thymic tissue taken at 1-2 weekly intervals up to tumor development was processed for light and electron microscopy, using glutaraldehyde-OsO4fixation and Epon-Araldite embedding.

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