Social stress increases tumor development: Effects of antalarmin, a CRF type 1 receptor antagonist, and nadolol, a beta-adrenergic antagonist

2006 ◽  
Vol 20 (3) ◽  
pp. 73 ◽  
Author(s):  
Oscar Vegas ◽  
Larraitz Garmendia ◽  
Arantza Azpiroz
1991 ◽  
Vol 324 (22) ◽  
pp. 1532-1538 ◽  
Author(s):  
Thierry Poynard ◽  
Paul Calès ◽  
Linda Pasta ◽  
Gaetano Ideo ◽  
Jean-Pierre Pascal ◽  
...  

2017 ◽  
Vol 19 (4-5) ◽  
pp. 295-301 ◽  
Author(s):  
Silene Macedo ◽  
João Paulo Ferreira Rodrigues ◽  
Sergio Schenkman ◽  
Nobuko Yoshida

1984 ◽  
Vol 246 (6) ◽  
pp. G654-G659
Author(s):  
H. Nagata ◽  
P. H. Guth

The effect of topical histamine on microvascular permeability to macromolecules was studied in the rat gastric mucosa using a fluorescent in vivo microscopy technique. Acid secretion was measured in the pylorus-ligated rat. A topical dose of 10(-2)M histamine increased acid output to a maximum, which was equal to the maximum values attained by intravenous or subcutaneous histamine. Only in rats pretreated with a beta-adrenergic antagonist did 10(-2) to 5 X 10(-2)M histamine cause leak of a fluorescein-albumin conjugate from mucosal microvessels. Leak occurred around collecting venules but not from capillaries. An H1-receptor antagonist, but not an H2-receptor antagonist, significantly decreased histamine-induced leaks. We concluded the following. 1) topically applied histamine penetrates into the mucosa and can increase acid secretion to the same extent as parenteral histamine. 2) Topical histamine increases microvascular permeability to macromolecules only when beta-adrenergic receptors are blocked. Larger doses of histamine are needed for initiating the permeability change than for initiating the acid secretory response. 3) H1-receptors in venules are involved in the histamine-induced increase in permeability.


2014 ◽  
Vol 260 ◽  
pp. 148-154 ◽  
Author(s):  
Patrick M. Hecht ◽  
Matthew J. Will ◽  
Todd R. Schachtman ◽  
Lauren M. Welby ◽  
David Q. Beversdorf

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