Effect of nutritional supplementations on physical performance and muscle strength parameters in older people: A systematic review and meta-analysis

2019 ◽  
Vol 51 ◽  
pp. 48-54 ◽  
Author(s):  
Nicola Veronese ◽  
Brendon Stubbs ◽  
Leonardo Punzi ◽  
Pinar Soysal ◽  
Raffaele Antonelli Incalzi ◽  
...  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Linqian Lu ◽  
Lin Mao ◽  
Yuwei Feng ◽  
Barbara E. Ainsworth ◽  
Yu Liu ◽  
...  

Abstract Objective We conducted a systematic review and meta-analysis to clarify the effects of different exercise modes (resistance training [RT], whole body vibration training [WBVT], and mixed training [MT, resistance training combined with other exercises such as balance, endurance and aerobic training]) on muscle strength (knee extension strength [KES]) and physical performance (Timed Up and Go [TUG], gait speed [GS] and the Chair Stand [CS]) in older people with sarcopenia. Method All studies published from January 2010 to March 2021 on the effects of exercise training in older people with sarcopenia were retrieved from 6 electronic databases: Pubmed, Cochrane Library, Embase, Web of Science, the China National Knowledge Infrastructure (CNKI), and Wanfang Database. Two researchers independently extracted and evaluated studies that met inclusion and exclusion criteria. Pooled analyses for pre- and post- outcome measurements were performed using Review Manager 5.4 with standardized mean differences (SMDs) and fixed-effect models. Result Twenty-six studies (25 randomized controlled trails [RCTs] and one non-randomized controlled trail) were included in this study with 1191 older people with sarcopenia (mean age 60.6 ± 2.3 to 89.5 ± 4.4). Compared with a control group, RT and MT significantly improved KES (RT, SMD = 1.36, 95% confidence intervals [95% CI]: 0.71 to 2.02, p < 0.0001, I2 = 72%; MT, SMD = 0.62, 95% CI: 0.29 to 0.95, p = 0.0002, I2 = 56%) and GS (RT, SMD = 2.01, 95% CI: 1.04 to 2.97, p < 0.0001, I2 = 84%; MT, SMD = 0.69, 95% CI: 0.29 to 1.09, p = 0.008, I2 = 81%). WBVT showed no changes in KES (SMD = 0.65, 95% CI: − 0.02 to 1.31, p = 0.06, I2 = 80%) or GS (SMD = 0.12, 95% CI: − 0.15 to 0.39, p = 0.38, I2 = 0%). TUG times were significantly improved with all exercise training modes (SMD = -0.66, 95% CI: − 0.94 to − 0.38, p < 0.00001, I2 = 60%). There were no changes in CS times with any of the exercise training modes (SMD = 0.11, 95% CI: − 0.36 to 0.57, p = 0.65, I2 = 87%). Conclusions In older people with sarcopenia, KES and GS can be improved by RT and MT, but not by WBVT. All three training modes improved TUG times, but not improved CS times.


2020 ◽  
Author(s):  
Mariana B de Moraes ◽  
Christina Avgerinou ◽  
Fernanda B Fukushima ◽  
Edison I O Vidal

Abstract Context Although nutrition is considered an important intervention for the management of frailty, the actual effectiveness of interventions addressing nutrition in frail older people remains unclear. Objective The aim for this systematic review was to appraise the evidence regarding the effectiveness of nutritional interventions for the management of frailty in older adults. Data Extraction We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The MEDLINE, Embase, Cumulative Index to Nursing and Allied Health Literature, Cochrane Central Register of Controlled Trials, Web of Science, and Latin American and Caribbean Health Sciences Literature databases were searched from January 2001 to November 2019. Two independent reviewers extracted relevant data. From 2370 initial records, 19 publications presenting data from 17 studies (1564 individuals; follow-up: 7–96 weeks) were included. Data Analysis None of the Bayesian random-effects meta-analyses comparing nutritional supplements with placebo regarding mortality, body mass index, weight, frailty status, muscle strength, gait speed, body composition, and cognitive function showed statistically significant differences. The same applies to a single meta-analysis comparing nutritional education with general health advice regarding muscle strength. Conclusion Our results suggest, mostly with low to very low degrees of certainty, that nutritional supplements or nutritional education delivered in isolation may not be effective for the management of frailty in older people. Review registration number CRD42018111510 (PROSPERO).


2020 ◽  
Author(s):  
Andrea Gonzalez ◽  
Mayalen Valero-Breton ◽  
Camila Huerta-Salgado ◽  
Oscar Achiardi ◽  
Felipe Simon ◽  
...  

Objective: To conduct a systematic review and meta-analyses to assess the efficacy of physical exercise on strength, muscle mass and physical function in adult patients with non-alcoholic fatty liver disease (NAFLD). Design: We conducted a systematic review and meta-analysis of seven studies to investigate the effect of exercise training interventions in muscle strength, muscle mass and physical performance. Data sources: We identified relevant randomised controlled trials (RCT) in electronic databases (PubMed, CINAHL and Scopus). Eligibility criteria: We selected seven RCTs from 66 screened studies. The inclusion criteria were peer-reviewed and English writing articles that included adult patients with liver disease of non-alcoholic origin, applied resistance training, endurance training or both, and assayed at least one variable of sarcopenia. Results: Physical performance criterion improved in the exercise groups (mean differences [MD] 8.26 mL/Kg*min [95% CI 5.27 to 11.24 mL/Kg*min], p < 0.0001) versus the control groups; muscle mass, determined as lean body mass (LBM), showed no evidence of the beneficial effects of exercise versus the control groups (MD 1.01 Kg [95% CI -1.78 to 3.80 Kg], p = 0.48); we did not include muscle strength, as none of the selected studies evaluated it. Summary/conclusion: Exercise training is a useful intervention strategy to treat sarcopenia in patients with NAFLD; it increases their physical performance in the form of aerobic capacity but does not affect LBM. Future research should include muscle strength assessments and resistance training to evaluate the effects of exercise training on sarcopenia in NAFLD patients. PROSPERO reference number CRD42020191471


2019 ◽  
Vol 50 (4) ◽  
pp. 291-302 ◽  
Author(s):  
Yue Lu ◽  
Yujie Wang ◽  
Qian Lu

Background: Lack of exercise is a prevalent problem in patients receiving dialysis. Although guidelines recommend these patients to undertake suitable exercise, no exercise type or intensity has been suggested, and the effect of exercise on muscle fitness in dialysis patients is not clear. This study investigated the effect of exercise on muscle fitness, including muscle mass, muscle strength, and physical performance, in patients on dialysis. Methods: A systematic review and a meta-analysis of randomized controlled trials (RCTs) were conducted. Five English and 4 Chinese databases were searched from their inception to July 2018. Two independent reviewers searched the different databases, selected trials, conducted bias assessment, and extracted the data. Results: A total of 21 RCTs meeting the inclusion criteria were included in this review. Pooled results demonstrated that resistance training significantly improved leg mass (standard mean difference [SMD] 0.34, 95% CI [0.06–0.62], p= 0.02) whereas aerobic training did not (SMD 0.87, 95% CI [–0.11 to 1.86], p = 0.08). Resistance training increased both grip strength (weighted mean difference [WMD] 4.71 kg, 95% CI [2.42–6.99], p < 0.00001) and knee extension strength (WMD 3.93 kg, 95% CI [0.59–7.28], p = 0.02) significantly. Aerobic training improved grip strength (WMD 7.70 kg, 95% CI [3.35–12.05], p= 0.005) and the time of finishing short version of the sit-to-stand test (STS; WMD –4.69 s, 95% CI [–9.01 to –0.38], p = 0.03) but with insufficient evidence. In the dimension of physical performance, both aerobic training and resistance training have some beneficial effect on improving the score of 6-min walking test (WMD 85.76 m, 95% CI [63.43–108.09], p < 0.00001; WMD 41.92 m, 95% CI [8.06–75.75], p = 0.02, respectively) and median version of STS test (WMD 4.30 repetitions, 95% CI [1.22–7.39], p = 0.006; WMD 2.60 repetitions, 95% CI [0.64–4.56], p = 0.006, respectively). Conclusions: Regular resistance training with a moderate to high intensity may lead to improvement in muscle mass and muscle strength of patients undergoing dialysis, especially for the trained muscles. Both aerobic training and resistance training may help dialysis patients improve physical performance.


Maturitas ◽  
2015 ◽  
Vol 82 (1) ◽  
pp. 72-84 ◽  
Author(s):  
Keith D. Hill ◽  
Susan W. Hunter ◽  
Frances A. Batchelor ◽  
Vinicius Cavalheri ◽  
Elissa Burton

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