The Symptom Inventory Disability-Specific Short Forms for Multiple Sclerosis: Construct Validity, Responsiveness, and Interpretation

2012 ◽  
Vol 93 (9) ◽  
pp. 1617-1628.e1 ◽  
Author(s):  
Carolyn E. Schwartz ◽  
Rita K. Bode ◽  
Brian R. Quaranto ◽  
Timothy Vollmer
Keyword(s):  
Multiple Sclerosis ◽  
Construct Validity ◽  
Symptom Inventory ◽  
Short Forms

scholarly journals Symbol Digit Modalities Test Variant in a Smartphone App for Persons With Multiple Sclerosis: Validation Study (Preprint)

2020 ◽  
Author(s):  
Pim van Oirschot ◽  
Marco Heerings ◽  
Karine Wendrich ◽  
Bram den Teuling ◽  
Marijn B Martens ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Construct Validity ◽  
Validation Study ◽  
Intraclass Correlation ◽  
Study Participant ◽  
Smartphone App ◽  
Retest Reliability ◽  
Matched Group ◽  
Test Retest Reliability ◽  
Study Participants

BACKGROUND The decline of cognitive processing speed (CPS) is a common dysfunction in persons with multiple sclerosis (MS). The Symbol Digit Modalities Test (SDMT) is widely used to formally quantify CPS. We implemented a variant of the SDMT in MS sherpa, a smartphone app for persons with MS. OBJECTIVE The aim of this study was to investigate the construct validity and test-retest reliability of the MS sherpa smartphone variant of the SDMT (sSDMT). METHODS We performed a validation study with 25 persons with relapsing-remitting MS and 79 healthy control (HC) subjects. In the HC group, 21 subjects were matched to the persons with MS with regard to age, gender, and education and they followed the same assessment schedule as the persons with MS (the “HC matched” group) and 58 subjects had a less intense assessment schedule to determine reference values (the “HC normative” group). Intraclass correlation coefficients (ICCs) were determined between the paper-and-pencil SDMT and its smartphone variant (sSDMT) on 2 occasions, 4 weeks apart. Other ICCs were determined for test-retest reliability, which were derived from 10 smartphone tests per study participant, with 3 days in between each test. Seven study participants with MS were interviewed regarding their experiences with the sSDMT. RESULTS The SDMT scores were on average 12.06% higher than the sSDMT scores, with a standard deviation of 10.68%. An ICC of 0.838 was found for the construct validity of the sSDMT in the combined analysis of persons with MS and HC subjects. Average ICCs for test-retest reliability of the sSDMT for persons with MS, the HC matched group, and the HC normative group were 0.874, 0.857, and 0.867, respectively. The practice effect was significant between the first and the second test of the persons with MS and the HC matched group and trivial for all other test-retests. The interviewed study participants expressed a positive attitude toward the sSDMT, but they also discussed the importance of adapting a smartphone cognition test in accordance with the needs of the individual persons with MS. CONCLUSIONS The high correlation between sSDMT and the conventional SDMT scores indicates a very good construct validity. Similarly, high correlations underpin a very good test-retest reliability of the sSDMT. We conclude that the sSDMT has the potential to be used as a tool to monitor CPS in persons with MS, both in clinical studies and in clinical practice.

Construct Validity of DSM-5 Level 2 Assessments (PROMIS Depression, Anxiety, and Anger): Evidence From the MMPI-2-RF

Assessment ◽  
2020 ◽  
pp. 107319112091109
Author(s):  
Anthony M. Tarescavage ◽  
Emma H. Forner ◽  
Yossef Ben-Porath
Keyword(s):  
Construct Validity ◽  
Convergent Validity ◽  
Minnesota Multiphasic Personality Inventory ◽  
Outcome Measurement ◽  
External Validation ◽  
Patient Reported Outcome ◽  
Measurement Information ◽  
Short Forms ◽  
Patient Reported ◽  
Future Revision

The Patient Reported Outcome Measurement Information System (PROMIS) is a NIH-funded measure that has item banks assessing a variety of physical, social, and mental health domains. Short forms from the emotional distress item bank (which includes measures of Depression, Anxiety, and Anger) were included in the Diagnostic and Statistical Manual for Mental Disorders–Fifth edition as emerging measures to be administered at intake to aid diagnosis and throughout treatment to track progress. The purpose of the current study was to further investigate the PROMIS distress item bank’s construct validity using the Minnesota Multiphasic Personality Inventory–2–Restructured Form (MMPI-2-RF). The sample included 344 college students (119 males, 225 females) who were administered the MMPI-2-RF and the PROMIS Anxiety, Anger, and Depression short forms. Zero-order correlations between the PROMIS scales and the Restructured Clinical Scales and Internalizing Specific Problems Scales were examined. Overall, these results suggest that scores from the PROMIS Anxiety, Anger, and Depression scales evidence convergent validity but have problematic construct validity (particularly for Depression). Future revision of the scales should be considered and sufficient external validation evidence should be available for review before psychological assessments are recommended and distributed for widespread clinical use.

Continued validation of the Symptom Inventory in multiple sclerosis

2009 ◽  
Vol 285 (1-2) ◽  
pp. 134-136 ◽  
Author(s):  
Robert W. Motl ◽  
Carolyn E. Schwartz ◽  
Timothy Vollmer
Keyword(s):  
Multiple Sclerosis ◽  
Symptom Inventory

scholarly journals The 27-Item Multiple Sclerosis Quality of Life Questionnaire: A New Brief Measure Including Treatment Burden and Work Life

2021 ◽  
Author(s):  
Helen Beckmann ◽  
Christoph Heesen ◽  
Matthias Augustin ◽  
Christine Blome
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Construct Validity ◽  
Convergent Validity ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
Patient Reported ◽  
Disease Specific

Abstract Background: Treatment- and work-related aspects have been neglected in health-related quality of life (HRQOL) measures in multiple sclerosis (MS). We aimed to develop a brief instrument covering all important impairment-, activity-, participation-, and treatment-related aspects for use in research and practice. Methods: The 27-item Multiple Sclerosis Quality of Life Questionnaire (MS-QLQ27) was developed using open item collection, a multidisciplinary expert panel, and cognitive pretesting. It was evaluated for reliability, construct validity, and responsiveness with 100 patients presenting with relapse (84 at follow-up ~14 days later). Construct validity was analyzed by correlating the MS-QLQ27 with the disease-specific Hamburg Quality of Life Questionnaire in MS (HAQUAMS) and generic HRQOL instuments. The Expanded Disability Status Scale (EDSS) was used to analyze known-groups validity. Responsiveness was determined as the correlation of changes in MS-QLQ27 scores with changes in validation criteria. Results: Internal consistency was high (Cronbach α = 0.94 at baseline and 0.93 at follow-up). Convergent validity was supported by direction and magnitude of associations with disease-specific and generic instruments. Correlations with change in convergent criteria were strong, indicating responsiveness. The HAQUAMS showed the strongest associations with the MSQLQ27. The MS-QLQ27 showed the highest effect size compared with other patient-reported outcomes and the EDSS. It successfully distinguished between levels of disease severity. Conclusions: These results indicate that the MS-QLQ27 is a reliable, valid, and highly responsive instrument for assessing HRQOL during relapse evolution in MS. Its advantages are that it is brief yet comprehensive, covering work- and treatment-related aspects not addressed in previous measures.

Reliability, Construct Validity, and Subscale Norms of the Brief Symptom Inventory When Administered to Bereaved Parents

1996 ◽  
Vol 4 (2) ◽  
pp. 117-127 ◽  
Author(s):  
L. Clark Johnson ◽  
Shirley A. Murphy ◽  
Margaret Dimond
Keyword(s):  
Construct Validity ◽  
Severity Index ◽  
Brief Symptom Inventory ◽  
Adolescent And Young Adult ◽  
Future Research ◽  
Summary Statistics ◽  
Global Severity Index ◽  
Symptom Inventory ◽  
Bereaved Parents ◽  
Community Standard

The Brief Symptom Inventory (BSI) was administered to parents (N = 260; 171 mothers and 89 fathers) whose adolescent and young adult children died unexpectedly and violently by accident, homicide, or suicide. Summary statistics and reliability coefficients (Cronbach’ s a) for the nine subscales and the Global Severity Index were calculated. A comparison of means and standard deviations confirmed the expectation that this sample is dramatically different from the normative American community standard. Raw scores for the subscales were transformed into standardized T scores and critical values for a screening heuristic presented. An attempt to obtain construct validity using factor analysis suggested that a five-factor solution provided a description of this population of bereaved parents that is more insightful than the nine standard subscales of the BSI. Implications for both clinicians and future research are discussed.

AB0755 Reliability and Construct Validity of the Psoriasis Symptom Inventory in Subjects with Psoriatic Arthritis

2014 ◽  
Vol 73 (Suppl 2) ◽  
pp. 1054.1-1054 ◽  
Author(s):  
P.J. Mease ◽  
M.C. Genovese ◽  
A. Mutebi ◽  
H. Wilson ◽  
D.A. Revicki ◽  
...  
Keyword(s):  
Psoriatic Arthritis ◽  
Construct Validity ◽  
Symptom Inventory
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