Coupling of two centrifugeless ultrasound-assisted dispersive solid/liquid phase microextractions as a highly selective, clean, and efficient method for determination of ultra-trace amounts of non-steroidal anti-inflammatory drugs in complicated matrices

2018 ◽  
Vol 997 ◽  
pp. 67-79 ◽  
Author(s):  
Somayeh Arghavani-Beydokhti ◽  
Maryam Rajabi ◽  
Alireza Asghari
Keyword(s):  
Liquid Phase ◽  
Efficient Method ◽  
Inflammatory Drugs ◽  
Ultrasound Assisted ◽  
Anti Inflammatory ◽  
Ultra Trace ◽  
Solid Liquid ◽  
Complicated Matrices

Dispersive suspended-solidified floating organic droplet microextraction of nonsteroidal anti-inflammatory drugs: comparison of suspended droplet-based and dispersive-based liquid-phase microextraction methods

RSC Advances ◽  
2015 ◽  
Vol 5 (129) ◽  
pp. 106574-106588 ◽  
Author(s):  
Behruz Barfi ◽  
Alireza Asghari ◽  
Maryam Rajabi ◽  
Nasim Mirkhani
Keyword(s):  
Liquid Phase ◽  
Human Plasma ◽  
Urine Samples ◽  
Liquid Phase Microextraction ◽  
Human Plasma And Urine ◽  
Plasma And Urine Samples ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Suspended Droplet

A dispersive suspended-solidified floating organic droplet microextraction method was developed for determination of some nonsteroidal anti-inflammatory drugs in human plasma and urine samples.

Capillary electrophoresis determination of nonsteroidal anti-inflammatory drugs in wastewater using hollow fiber liquid-phase microextraction

2011 ◽  
Vol 32 (16) ◽  
pp. 2107-2113 ◽  
Author(s):  
Mercedes Villar Navarro ◽  
María Ramos Payán ◽  
Rut Fernández-Torres ◽  
Miguel A. Bello-López ◽  
Manuel Callejón Mochón ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Liquid Phase ◽  
Hollow Fiber ◽  
Liquid Phase Microextraction ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Multi-walled Carbon Nanotubes Reinforced into Hollow Fiber by Chitosan Sol-gel for Solid/Liquid Phase Microextraction of NSAIDs from Urine Prior to HPLC-DAD Analysis

2019 ◽  
Vol 20 (5) ◽  
pp. 390-400 ◽  
Author(s):  
Nabil N. AL-Hashimi ◽  
Amjad H. El-Sheikh ◽  
Rania F. Qawariq ◽  
Majed H. Shtaiwi ◽  
Rowan AlEjielat
Keyword(s):  
Carbon Nanotubes ◽  
Liquid Phase ◽  
Hollow Fiber ◽  
Sol Gel ◽  
Liquid Phase Microextraction ◽  
Extraction Device ◽  
Multi Walled Carbon Nanotubes ◽  
Solid Liquid ◽  
Walled Carbon Nanotubes

Background: The efficient analytical method for the analysis of nonsteroidal antiinflammatory drugs (NSAIDs) in a biological fluid is important for determining the toxicological aspects of such long-term used therapies. Methods: In the present work, multi-walled carbon nanotubes reinforced into a hollow fiber by chitosan sol-gel assisted-solid/ liquid phase microextraction (MWCNTs-HF-CA-SPME) method followed by the high-performance liquid chromatography-diode array detection (HPLC–DAD) was developed for the determination of three NSAIDs, ketoprofen, diclofenac, and ibuprofen in human urine samples. MWCNTs with various dimensions were characterized by various analytical techniques. The extraction device was prepared by immobilizing the MWCNTs in the pores of 2.5 cm microtube via chitosan sol-gel assisted technology while the lumen of the microtube was filled with few microliters of 1-octanol with two ends sealed. The extraction device was operated by direct immersion in the sample solution. Results: The main factors influencing the extraction efficiency of the selected NSAIDs have been examined. The method showed good linearity R2 ≥ 0.997 with RSDs from 1.1 to 12.3%. The limits of detection (LODs) were 2.633, 2.035 and 2.386 µg L-1, for ketoprofen, diclofenac, and ibuprofen, respectively. The developed method demonstrated a satisfactory result for the determination of selected drugs in patient urine samples and comparable results against reference methods. Conclusion: The method is simple, sensitive and can be considered as an alternative for clinical laboratory analysis of selected drugs.

Drug-loading colloidal gels assembled from polymeric nanoparticles as an anti-inflammatory platform

2021 ◽  
Author(s):  
Jinkun Yin ◽  
Yaoqing Chu ◽  
Si-Jian Pan ◽  
Lianjiang Tan
Keyword(s):  
Efficient Method ◽  
Polymeric Nanoparticles ◽  
Drug Loading ◽  
Direct Injection ◽  
Colloidal Gels ◽  
Local Inflammation ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Precise treatment of local inflammation is always challenging. Administration of anti-inflammatory drugs by direct injection has been considered as an efficient method for inflammation inhibition. In the present work, injectable...

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