Electrochemical detection of Cd(ii) ions in complex matrices with nanopipets

A nanopipet electrochemical sensor was successfully utilized to detect free Cd(ll) ions in complicated matrices and real environmental water samples.

Application of Tandem Dispersive Liquid–Liquid Microextraction as an Efficient Method for Preconcentration of Two Antidepressant Drugs in Real Samples Combined with High Performance Liquid Chromatography

In the present work, tandem dispersive liquid–liquid microextraction (TDLLME) coupled with liquid chromatography was used for the determination of the two antidepressant drugs citalopram (CIT) and sertraline (SER) in complicated matrices. Indeed, the present approach was used to improve the suitability and appropriateness of the dispersive liquid–liquid microextraction (DLLME) method in complicated matrices. Firstly, 10 mL of the sample solution containing the two understudied drugs was extracted into an organic solvent (200 μL of 1,2-dichloromethane) using the DLLME method. Then the extracted analytes were back-extracted into 100 μL of an aqueous acceptor phase. The total extraction time of this method is about 6 min. To achieve the best efficiency for this method, efficient parameters like the kind and volume of the organic solvent and the effect of the ionic strength on the effectiveness of extraction were reviewed and improved. Under the optimized experimental conditions, TDLLME showed good linearity in the range of 100.0–7000.0 ng mL−1. The limits of detection were found to be 10.0 ng mL−1 for CIT and 2.0 ng mL−1 for SER. The relative standard deviation (RSD) is obtained in the range of 0.7–4.1%.

Displacement chemistry-based nanopore analysis of nucleic acids in complicated matrices

The matrix effect on nanopore stochastic sensing of nucleic acids could be overcome by taking advantage of displacement chemical reaction.