Abnormality of vascular elastic fibers in the macular mouse and a patient with Menkes' disease: ultrastructural and immunohistochemical study

2002 ◽  
Vol 35 (1) ◽  
pp. 24-30 ◽  
Author(s):  
H. Murakami ◽  
Hiroko Kodama ◽  
Norimichi Nemoto
Keyword(s):  
Immunohistochemical Study ◽  
Menkes Disease ◽  
Elastic Fibers ◽  
Macular Mouse

scholarly journals Immunohistochemical Study of Extracellular Matrices and Elastic Fibers in a Human Sternoclavicular Joint

1997 ◽  
Vol 74 (5) ◽  
pp. 171-179 ◽  
Author(s):  
Kazuyuki SHIMADA ◽  
Naotoshi TAKESHIGE ◽  
Hiroshi MORIYAMA ◽  
Yasushi MIYAUCHI ◽  
Shigetaka SHIMADA ◽  
...  
Keyword(s):  
Immunohistochemical Study ◽  
Sternoclavicular Joint ◽  
Extracellular Matrices ◽  
Elastic Fibers

scholarly journals Immunohistochemical Study of the Goat Ductus deferens

2018 ◽  
Vol 62 (1) ◽  
pp. 11-17
Author(s):  
E. Marettová ◽  
M. Maretta
Keyword(s):  
Smooth Muscle ◽  
Positive Reaction ◽  
Immunohistochemical Study ◽  
Smooth Muscle Actin ◽  
Elastic Fibers ◽  
Cytokeratin 18 ◽  
Ductus Deferens ◽  
Blood Capillaries ◽  
Tunica Adventitia ◽  
Tunica Muscularis

Abstract Ductus deferens plays an important role in sperm transport and participates in the preservation of structure, maturation, and viability of sperm. In this study, we have immunohistochemically examined the ductus deferens in the goat. For immunohistochemical study the following monoclonal antibodies were used: cytokeratin 18, α-smooth muscle actin (α-SMA), vimentin and elastin. Morphologically, three distinct layers were identified in the goat ductus deferens — tunica mucosa, tunica muscularis and tunica adventitia. The epithelium of the mucosa was intensely stained with cytokeratin 18 (CK 18). The fibroblasts in the lamina propria and blood capillaries in the muscle layer showed positive reaction for vimentin. A positive reaction for α-SMA was observed in the smooth muscle cells of the tunica muscularis in the internal, middle and outer sublayers. An intense positive reaction for α-SMA was observed in the wall of the blood vessels. Elastic fibers in the form of a loose meshwork were present in all three layers. The high density of elastic fibers were found in the tunica adventitia.

Topographic Association of Fibronectin with Elastic Fibers in the Arterial Wall. An Immunohistochemical Study

1981 ◽  
Vol 8 (3-4) ◽  
pp. 199-204 ◽  
Author(s):  
P. G. Natali ◽  
D. Galloway ◽  
M. R. Nicotra ◽  
C. De Martino
Keyword(s):  
Arterial Wall ◽  
Immunohistochemical Study ◽  
Elastic Fibers

scholarly journals Occurrence of two missense mutations in Cu-ATPase of the macular mouse, a menkes disease model

IUBMB Life ◽  
1997 ◽  
Vol 43 (4) ◽  
pp. 913-918 ◽  
Author(s):  
Yuriko Ohta ◽  
Noriyuki Shiraishi ◽  
Morimitsu Nishikimi
Keyword(s):  
Disease Model ◽  
Menkes Disease ◽  
Missense Mutations ◽  
Macular Mouse

Effect of copper and disulfiram combination therapy on the macular mouse, a model of Menkes disease

2012 ◽  
Vol 26 (2-3) ◽  
pp. 105-108 ◽  
Author(s):  
Wattanaporn Bhadhprasit ◽  
Hiroko Kodama ◽  
Chie Fujisawa ◽  
Tomoko Hiroki ◽  
Eishin Ogawa
Keyword(s):  
Combination Therapy ◽  
Menkes Disease ◽  
Macular Mouse ◽  
Effect Of Copper

scholarly journals Menkes disease: Oral administration of glyoxal-bis(N(4)-methylthiosemicarbazonato)-copper(II) rescues the macular mouse

2018 ◽  
Vol 84 (5) ◽  
pp. 770-777 ◽  
Author(s):  
Mitsutoshi Munakata ◽  
Hiroko Kodama ◽  
Norihiko Tani ◽  
Kazuhiko Kimura ◽  
Hideyo Takahashi ◽  
...  
Keyword(s):  
Oral Administration ◽  
Menkes Disease ◽  
Macular Mouse

Mottled gene expression and copper distribution in the macular mouse, an animal model for Menkes disease

1998 ◽  
Vol 21 (3) ◽  
pp. 199-202 ◽  
Author(s):  
Y. Murata ◽  
H. Kodama ◽  
Y. Mori ◽  
M. Kobayashi ◽  
T. Abe
Keyword(s):  
Gene Expression ◽  
Animal Model ◽  
Menkes Disease ◽  
Macular Mouse ◽  
Copper Distribution

scholarly journals Mutation Analysis and Expression of the Mottled Gene in the Macular Mouse Model of Menkes Disease

1997 ◽  
Vol 42 (4) ◽  
pp. 436-442 ◽  
Author(s):  
Yoshiko Murata ◽  
Hiroko Kodama ◽  
Toshiaki Abe ◽  
Norio Ishida ◽  
Masahiko Nishimura ◽  
...  
Keyword(s):  
Mouse Model ◽  
Mutation Analysis ◽  
Menkes Disease ◽  
Macular Mouse

Genetic expression of Menkes disease in cultured astrocytes of the macular mouse

1991 ◽  
Vol 14 (6) ◽  
pp. 896-901 ◽  
Author(s):  
H. Kodama ◽  
Y. Meguro ◽  
T. Abe ◽  
M. H. Rayner ◽  
K. T. Suzuki ◽  
...  
Keyword(s):  
Menkes Disease ◽  
Genetic Expression ◽  
Cultured Astrocytes ◽  
Macular Mouse
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