Insulin, glucose and glycated hemoglobin in Alzheimer’s and vascular dementia with and without superimposed Type II diabetes mellitus condition

2007 ◽  
Vol 115 (1) ◽  
pp. 77-84 ◽  
Author(s):  
R. O. Domínguez ◽  
E. R. Marschoff ◽  
E. M. Guareschi ◽  
M. G. Repetto ◽  
A. L. Famulari ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Vascular Dementia ◽  
Type Ii Diabetes ◽  
Glycated Hemoglobin ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii

INFLUENCE OF THIOCTIC ACID N LABORATORY INDICATORS OF CARBOHYDRATE EXCHANGE IN PATIENTS WITH TYPE II DIABETES MELLITUS

2021 ◽  
pp. 29-35
Author(s):  
Kim V.S. ◽  
Abramova A.N. ◽  
Shur Yu.V. ◽  
Selezneva T.E. ◽  
Tsibizova A.A. ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Carbohydrate Metabolism ◽  
Type Ii Diabetes ◽  
Glycated Hemoglobin ◽  
Type Ii Diabetes Mellitus ◽  
Metformin Hydrochloride ◽  
Thioctic Acid ◽  
Type Ii ◽  
Hypoglycemic Agent ◽  
Normal Body Weight

The work is devoted to assessing the effect of thioctic acid on the main laboratory parameters of carbohydrate metabolism (blood glucose, C-peptide and insulin levels, glycated hemoglobin) in diabetes mellitus against the background of glucose-lowering therapy with metformin hydrochloride. The studies were conducted with the participation of 32 volunteers aged 52 to 63 years, 26 of whom type II diabetes mellitus proceeded with III-degree obesity. At the time of the study, all patients were taking metformin hydrochloride (MH) as a hypoglycemic agent. The experiment was carried out for 3 months. All study participants were divided into groups: the first group - the control group, who took only MG 850 mg once a day for; the second group, patients with normal body weight, who took metformin hydrochloride 850 mg and thioctic acid (TA) 600 mg per day; the third group - obese patients receiving the test compound at the same dosage. After 3 months of treatment, all patients underwent biochemical blood tests for the following parameters: blood glucose, glycated hemoglobin, C-peptide and insulin levels. The results obtained indicate that thioctic acid contributed to a more pronounced decrease in carbohydrate metabolism in comparison with the group of patients receiving only MH as a hypoglycemic agent. It was noted that the normalization of the studied parameters was expressed in the group of patients with normal body weight. Thus, the additional introduction of thioctic acid into the treatment regimen for patients with type II diabetes mellitus contributes to a more effective decrease in carbohydrate metabolism and compensation of the disease in comparison with standard therapy.

Clinical Study of Ultrasonic Extreme Velocity Imaging Pulse Wave Technique in Carotid Elasticity in Patients with Type II Diabetes Mellitus

2021 ◽  
Vol 11 (6) ◽  
pp. 1138-1143
Author(s):  
Fang Ma ◽  
Jimei Xu ◽  
Weiwei Yang ◽  
Fuqin Bian
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Type Ii Diabetes ◽  
Pulse Wave ◽  
Glycated Hemoglobin ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Carotid Imt ◽  
Wave Technology ◽  
Biochemical Indices

In this study, extreme velocity ultrasonic imaging pulse wave technology was used to detect the main indices of atherosclerosis such as carotid intima-media thickness (IMT) and carotid elasticity, and biochemical indices such as glycated hemoglobin, blood glucose and blood lipids in one hundred twenty 18–60-year-old patients with type II diabetes mellitus (T2DM) and 120 healthy controls. We analyzed the correlations between carotid elasticity, carotid IMT, and a range of biochemical indices. The results indicated that when the carotid IMT in young and middle-aged patients with T2DM was within the normal range (0.56±0.03 mm), the carotid artery elasticity was abnormal [Pulse wave propagation velocity (PWV)-BS = 7.69± 1.26 m/s; PWV-ES = 8.34±1.51 m/s; P < 0.05]. Additionally, PWV-BS was positively correlated with age, course of the disease, glycated hemoglobin (HbA1c), and fasting blood glucose (FBG) (r = 0.297, 0.377, 0.369, 0.382), and PWV-ES was positively correlated with age, course of the disease, HbA1c, and FBG (r = 0.318, 0.386, 0.392, 0.339). This finding provides a basis for extreme velocity ultrasonic imaging pulse wave technology to become a new method for the early screening of atherosclerosis in patients with T2DM; this is important for timely clinical intervention in patients with T2DM.

Prevalence and Severity of Periodontal Disease in Type II Diabetes Mellitus (Noninsulin-dependent Diabetes Mellitus) Patients in Gulbarga, Karnataka, India: An Epidemiological Study

2013 ◽  
Vol 3 (1) ◽  
pp. 32-35 ◽  
Author(s):  
Veena Ashok Patil ◽  
Roopashree Shivaraya ◽  
Manthan Hemant Desai
Keyword(s):  
Diabetes Mellitus ◽  
Periodontal Disease ◽  
Oral Hygiene ◽  
Type Ii Diabetes ◽  
Glycated Hemoglobin ◽  
Type Ii Diabetes Mellitus ◽  
Dependent Diabetes Mellitus ◽  
Diabetic Patients ◽  
Type Ii ◽  
Oral Hygiene Habits

ABSTRACT Background/objectives The objective was to study the prevalence and severity of periodontal disease in type II DM patients in Gulbarga, Karnataka, India. Materials and Methods A total of 100 type II DM patients and 100 nondiabetic patients with age group of 35 to 75 years were examined. The study group was divided into well, moderate and poorly controlled diabetes based on glycated hemoglobin (HbA1C) levels. Information regarding age, oral hygiene habits, personal habits, diabetic status and mode of diabetic therapy was obtained. Community periodontal index of treatment needs (CPITN) was used to assess the periodontal status. The results were statistically evaluated. Results The mean CPITN score and the number of missing teeth was higher in diabetics compared to nondiabetics and was statistically significant (p = 0.05). The prevalence of periodontal disease was found to be more frequent and severe in diabetic patients as compared to nondiabetics. The risk factors like glycated hemoglobin HbA1C, duration of diabetes, personal habits and oral hygiene habits showed a positive correlation with periodontal destruction, whereas mode of diabetic therapy showed negative correlation with the periodontal status. Conclusion Diabetic patients showed higher prevalence and severity of periodontal disease compared to nondiabetics. How to cite this article Patil VA, Shivaraya R, Desai MH. Prevalence and Severity of Periodontal Disease in Type II Diabetes Mellitus (Noninsulin-dependent Diabetes Mellitus) Patients in Gulbarga, Karnataka, India: An Epidemiological Study. J Contemp Dent 2013;3(1):32-35.

scholarly journals Association between Salivary Fructosamine, Plasma Glycated Hemoglobin, and Plasma Glucose Levels among Type II Diabetes Mellitus and Nondiabetic Individuals—A Cross-sectional Study

2019 ◽  
Vol 13 (03) ◽  
pp. 310-317 ◽  
Author(s):  
Sadhana Kandavel ◽  
P.D Madan Kumar
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
Glycated Hemoglobin ◽  
Positive Association ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Cross Sectional ◽  
Group I ◽  
Study Results ◽  
Group Ii

Abstract Objective The study was aimed to determine the association between salivary fructosamine and plasma glycated hemoglobin, plasma fasting and postprandial glucose levels among patients suffering from type II diabetes mellitus and nondiabetic healthy individuals. Materials and Methods The cross-sectional study was conducted in a hospital setting. A total of 100 participants were included, with 50 participants in each group—group I (patients with type II diabetes mellitus) and group II (nondiabetic healthy individuals). Blood and saliva samples were collected to estimate the levels of the blood and salivary parameters. Depending upon the normality, appropriate tests were used—t-test and Mann–Whitney U test were used for continuous data. Pearson chi-square test and Fisher's exact test were used for discrete data. To test for any positive association between salivary and blood parameters, simple linear regression was carried out. Results The study results showed that group I had significantly higher levels of salivary fructosamine when compared to group II (p < 0.001). In groups I and II a significant positive association was observed between salivary fructosamine and plasma glycated hemoglobin (group I, r-value 0.893; group II, r-value 0.307). Conclusion The overall study results showed that salivary fructosamine levels were significantly higher in patients with diabetes when compared to nondiabetic individuals. Also, positive correlation was observed between salivary fructosamine, plasma fasting, plasma postprandial, and plasma glycated hemoglobin among both the groups.

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