Is there an interchromosomal effect in reciprocal translocation carriers? Sperm FISH studies

2000 ◽  
Vol 107 (1) ◽  
pp. 95-95
Author(s):  
Anna M. Estop ◽  
Kathy Cieply ◽  
Santiago Munne ◽  
Urvashi Surti ◽  
Anthony Wakim ◽  
...  
Keyword(s):  
Reciprocal Translocation ◽  
Interchromosomal Effect ◽  
Sperm Fish

Is there an interchromosomal effect in reciprocal translocation carriers? Sperm FISH studies

2000 ◽  
Vol 106 (5) ◽  
pp. 517-524 ◽  
Author(s):  
Anna M. Estop ◽  
Kathy Cieply ◽  
Santiago Munne ◽  
Urvashi Surti ◽  
Anthony Wakim ◽  
...  
Keyword(s):  
Reciprocal Translocation ◽  
Interchromosomal Effect ◽  
Sperm Fish

Is there an interchromosomal effect in reciprocal translocation carriers? Sperm FISH studies

2000 ◽  
Vol 107 (1) ◽  
pp. 95-95
Author(s):  
Anna Estop ◽  
Kathy Cieply ◽  
Santiago Munne ◽  
Urvashi Surti ◽  
Anthony Wakim ◽  
...  
Keyword(s):  
Reciprocal Translocation ◽  
Interchromosomal Effect ◽  
Sperm Fish

Genotype-dependent interchromosomal effects of a grasshopper reciprocal translocation

Genome ◽  
1990 ◽  
Vol 33 (4) ◽  
pp. 538-541 ◽  
Author(s):  
P. Arana ◽  
N. Henriques-Gil ◽  
J. L. Santos
Keyword(s):  
Reciprocal Translocation ◽  
Chiasma Frequency ◽  
Genetic Background ◽  
Eyprepocnemis Plorans ◽  
Interchromosomal Effect ◽  
The Family ◽  
The Mean

The existence of interchromosomal effects has been tested in four segregating families of the grasshopper Eyprepocnemis plorans carrying the same translocation. The comparisons between the mean chiasma frequencies in the translocation heterozygotes and the standard homozygotes have revealed different responses, depending on the family: both significant increases and decreases in those bivalents not involved in the translocation have been found. A dependence of interchromosomal effects on genetic background is suggested.Key words: translocation, chiasma frequency, interchromosomal effect.

Is the interchromosomal effect present in embryos derived from Robertsonian and reciprocal translocation carriers particularly focusing on chromosome 10 rearrangements?

Zygote ◽  
2014 ◽  
Vol 23 (6) ◽  
pp. 908-915 ◽  
Author(s):  
Pinar Tulay ◽  
Meral Gultomruk ◽  
Necati Findikli ◽  
Erbil Yagmur ◽  
Mustafa Bahceci
Keyword(s):  
Reciprocal Translocation ◽  
Genetic Diagnosis ◽  
Preimplantation Genetic Screening ◽  
Preimplantation Embryos ◽  
Control Group ◽  
Cleavage Stage ◽  
Chromosome 10 ◽  
Aneuploidy Screening ◽  
Interchromosomal Effect ◽  
Aneuploidy Rate

SummaryThe aim of this study was to analyse the possible occurrence of the interchromosomal effect (ICE) in human preimplantation embryos obtained from Robertsonian and reciprocal translocation carriers focusing on ones with chromosome 10 rearrangements who were undergoing preimplantation genetic diagnosis (PGD) and to investigate whether offering aneuploidy screening would be beneficial to these patients. Cleavage stage embryos from translocation carriers undergoing PGD were biopsied. Multicolour fluorescence in situ hybridisation for the chromosomes involved in the translocation in addition to nine more chromosomes (13, 15, 16, 17, 18, 21, 22, X and Y) was used in the analysis. The control group involved embryos obtained from age-matched patients undergoing preimplantation genetic screening (PGS). Cumulative aneuploidy rate in embryos derived from both Robertsonian and reciprocal translocation carriers was found to be similar with the control group. Therefore no ICE was observed in cleavage stage embryos obtained from these carriers. More than half of the embryos with chromosome 10 rearrangements had aneuploidy for which an increased aneuploidy rate was more apparent in male carriers. Thus, it is possible that there is a risk of ICE in reciprocal carriers with chromosome 10 rearrangements. This study showed that there is no ICE in embryos derived from Robertsonian and reciprocal translocation carriers. However high rates of aneuploidy in structurally normal chromosomes were detected in embryos derived from these carriers and thus aneuploidy screening in addition to PGD may increase the pregnancy rates of these patients.

Analysis Using Sperm-FISH of a Putative Interchromosomal Effect in Boars Carrying Reciprocal Translocations

2009 ◽  
Vol 126 (1-2) ◽  
pp. 194-201 ◽  
Author(s):  
A. Bonnet-Garnier ◽  
S. Guardia ◽  
A. Pinton ◽  
A. Ducos ◽  
M. Yerle
Keyword(s):  
Reciprocal Translocations ◽  
Interchromosomal Effect ◽  
Sperm Fish

The weight of the interchromosomal effect in reciprocal translocation carriers

2016 ◽  
Vol 106 (3) ◽  
pp. e369-e370
Author(s):  
T. Escudero ◽  
L. Ribustello ◽  
E.M. Armenti ◽  
E. Liu ◽  
J. Grifo ◽  
...  
Keyword(s):  
Reciprocal Translocation ◽  
Interchromosomal Effect
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