Maintenance of myoglobin concentration in human skeletal muscle after heavy resistance training

1999 ◽  
Vol 79 (4) ◽  
pp. 347-352 ◽  
Author(s):  
Kazumi Masuda ◽  
Jo Yoen Choi ◽  
Hitoshi Shimojo ◽  
Shigeru Katsuta
Keyword(s):  
Skeletal Muscle ◽  
Resistance Training ◽  
Human Skeletal Muscle ◽  
Heavy Resistance Training

scholarly journals Resistance exercise alters MRF and IGF-I mRNA content in human skeletal muscle

2003 ◽  
Vol 95 (3) ◽  
pp. 1038-1044 ◽  
Author(s):  
Niklas Psilander ◽  
Rasmus Damsgaard ◽  
Henriette Pilegaard
Keyword(s):  
Skeletal Muscle ◽  
Resistance Training ◽  
Resistance Exercise ◽  
Human Skeletal Muscle ◽  
Mrna Level ◽  
Vastus Lateralis Muscle ◽  
Mrna Levels ◽  
Igf I ◽  
Mrna Content ◽  
Heavy Resistance Training

Increasing evidence suggests that the myogenic regulatory factors (MRFs) and IGF-I have important roles in the hypertrophy response observed after mechanical loading. We, therefore, hypothesized that a bout of heavy-resistance training would affect the MRF and IGF-I mRNA levels in human skeletal muscle. Six male subjects completed four sets of 6-12 repetitions on a leg press and knee extensor machine separated by 3 min. Myogenin, MRF4, MyoD, IGF-IEabc (isoforms a, b, and c) and IGF-IEbc (isoform b and c) mRNA levels were determined in the vastus lateralis muscle by RT-PCR before exercise, immediately after, and 1, 2, 6, 24, and 48 h postexercise. Myogenin, MyoD, and MRF4 mRNA levels were elevated ( P < 0.005) by 100-400% 0-24 h postexercise. IGF-IEabc mRNA content decreased ( P < 0.005) by ∼44% after 1 and 6 h of recovery. The IGF-IEbc mRNA level was unaffected. The present study shows that myogenin, MyoD, and MRF4 mRNA levels are transiently elevated in human skeletal muscle after a single bout of heavy-resistance training, supporting the idea that the MRFs may be involved in regulating hypertrophy and/or fiber-type transitions. The results also suggest that IGF-IEa expression may be downregulated at the mRNA level during the initial part of recovery from resistance exercise.

scholarly journals Acute and Chronic Resistance-Training Downregulates Select Line-1 Retrotransposon Activity Markers in Human Skeletal Muscle

2018 ◽  
Vol 50 (5S) ◽  
pp. 553
Author(s):  
Matthew A. Romero ◽  
C. Brooks Mobley ◽  
Paul A. Roberson ◽  
Cody T. Haun ◽  
Wesley C. Kephart ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Resistance Training ◽  
Human Skeletal Muscle ◽  
Retrotransposon Activity

The expression of neuregulin and erbB receptors in human skeletal muscle: effects of progressive resistance training

2005 ◽  
Vol 94 (4) ◽  
pp. 371-375 ◽  
Author(s):  
Nathan K. LeBrasseur ◽  
Kelly C. Mizer ◽  
Jascha D. Parkington ◽  
Douglas B. Sawyer ◽  
Roger A. Fielding
Keyword(s):  
Skeletal Muscle ◽  
Resistance Training ◽  
Human Skeletal Muscle ◽  
Erbb Receptors ◽  
Progressive Resistance Training ◽  
Progressive Resistance

scholarly journals Do PTK2 gene polymorphisms contribute to the interindividual variability in muscle strength and the response to resistance training? A preliminary report

2012 ◽  
Vol 112 (8) ◽  
pp. 1329-1334 ◽  
Author(s):  
Robert M. Erskine ◽  
Alun G. Williams ◽  
David A. Jones ◽  
Claire E. Stewart ◽  
Hans Degens
Keyword(s):  
Skeletal Muscle ◽  
Resistance Training ◽  
Muscle Strength ◽  
Human Skeletal Muscle ◽  
Interindividual Variability ◽  
Knee Extension ◽  
Joint Torque ◽  
Specific Force ◽  
Tyrosine Kinase 2 ◽  
The Impact

The protein tyrosine kinase-2 (PTK2) gene encodes focal adhesion kinase, a structural protein involved in lateral transmission of muscle fiber force. We investigated whether single-nucleotide polymorphisms (SNPs) of the PTK2 gene were associated with various indexes of human skeletal muscle strength and the interindividual variability in the strength responses to resistance training. We determined unilateral knee extension single repetition maximum (1-RM), maximum isometric voluntary contraction (MVC) knee joint torque, and quadriceps femoris muscle specific force (maximum force per unit physiological cross-sectional area) before and after 9 wk of knee extension resistance training in 51 untrained young men. All participants were genotyped for the PTK2 intronic rs7843014 A/C and 3′-untranslated region (UTR) rs7460 A/T SNPs. There were no genotype associations with baseline measures or posttraining changes in 1-RM or MVC. Although the training-induced increase in specific force was similar for all PTK2 genotypes, baseline specific force was higher in PTK2 rs7843014 AA and rs7460 TT homozygotes than in the respective rs7843014 C- ( P = 0.016) and rs7460 A-allele ( P = 0.009) carriers. These associations between muscle specific force and PTK2 SNPs suggest that interindividual differences exist in the way force is transmitted from the muscle fibers to the tendon. Therefore, our results demonstrate for the first time the impact of genetic variation on the intrinsic strength of human skeletal muscle.

Changes in Satellite Cell and Myonuclei Number in Human Skeletal Muscle with Resistance Training

2006 ◽  
Vol 38 (Supplement) ◽  
pp. S9
Author(s):  
Per Aagaard ◽  
Steen Olsen ◽  
Fawzi Kadi ◽  
Goran Tufekovic ◽  
Julien Verney ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Resistance Training ◽  
Satellite Cell ◽  
Human Skeletal Muscle
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