scholarly journals Ribosome biogenesis and resistance training volume in human skeletal muscle

2020 ◽  
Vol 598 (6) ◽  
pp. 1121-1122 ◽  
Author(s):  
Robert Solsona ◽  
Anthony M. J. Sanchez
2018 ◽  
Vol 50 (5S) ◽  
pp. 553
Author(s):  
Matthew A. Romero ◽  
C. Brooks Mobley ◽  
Paul A. Roberson ◽  
Cody T. Haun ◽  
Wesley C. Kephart ◽  
...  

2005 ◽  
Vol 94 (4) ◽  
pp. 371-375 ◽  
Author(s):  
Nathan K. LeBrasseur ◽  
Kelly C. Mizer ◽  
Jascha D. Parkington ◽  
Douglas B. Sawyer ◽  
Roger A. Fielding

2012 ◽  
Vol 112 (8) ◽  
pp. 1329-1334 ◽  
Author(s):  
Robert M. Erskine ◽  
Alun G. Williams ◽  
David A. Jones ◽  
Claire E. Stewart ◽  
Hans Degens

The protein tyrosine kinase-2 (PTK2) gene encodes focal adhesion kinase, a structural protein involved in lateral transmission of muscle fiber force. We investigated whether single-nucleotide polymorphisms (SNPs) of the PTK2 gene were associated with various indexes of human skeletal muscle strength and the interindividual variability in the strength responses to resistance training. We determined unilateral knee extension single repetition maximum (1-RM), maximum isometric voluntary contraction (MVC) knee joint torque, and quadriceps femoris muscle specific force (maximum force per unit physiological cross-sectional area) before and after 9 wk of knee extension resistance training in 51 untrained young men. All participants were genotyped for the PTK2 intronic rs7843014 A/C and 3′-untranslated region (UTR) rs7460 A/T SNPs. There were no genotype associations with baseline measures or posttraining changes in 1-RM or MVC. Although the training-induced increase in specific force was similar for all PTK2 genotypes, baseline specific force was higher in PTK2 rs7843014 AA and rs7460 TT homozygotes than in the respective rs7843014 C- ( P = 0.016) and rs7460 A-allele ( P = 0.009) carriers. These associations between muscle specific force and PTK2 SNPs suggest that interindividual differences exist in the way force is transmitted from the muscle fibers to the tendon. Therefore, our results demonstrate for the first time the impact of genetic variation on the intrinsic strength of human skeletal muscle.


2006 ◽  
Vol 38 (Supplement) ◽  
pp. S9
Author(s):  
Per Aagaard ◽  
Steen Olsen ◽  
Fawzi Kadi ◽  
Goran Tufekovic ◽  
Julien Verney ◽  
...  

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0176609 ◽  
Author(s):  
Lena Willkomm ◽  
Sebastian Gehlert ◽  
Daniel Jacko ◽  
Thorsten Schiffer ◽  
Wilhelm Bloch

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