Chromosomal location and tissue expression of the gene encoding the adenovirus E1A-regulated transcription factor E4F in humans and mice

1998 ◽  
Vol 9 (4) ◽  
pp. 320-323 ◽  
Author(s):  
Robert J. Rooney ◽  
Rachael R. Daniels ◽  
Nancy A. Jenkins ◽  
Debra J. Gilbert ◽  
Kristen Rothammer ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Chromosomal Location ◽  
Tissue Expression ◽  
Gene Encoding ◽  
Adenovirus E1a

scholarly journals Genomic Structure and Chromosomal Location of the Rat Gene Encoding the Zinc Finger Transcription Factor Kid-1

Genomics ◽  
1994 ◽  
Vol 20 (2) ◽  
pp. 203-209 ◽  
Author(s):  
Ralph Witzgall ◽  
Rüdiger Volk ◽  
Raymond S. Yeung ◽  
Joseph V. Bonventre
Keyword(s):  
Transcription Factor ◽  
Zinc Finger ◽  
Chromosomal Location ◽  
Genomic Structure ◽  
Gene Encoding ◽  
Zinc Finger Transcription Factor

Structure, expression, chromosomal location and product of the gene encoding Adh2 in Petunia.

Genetics ◽  
1993 ◽  
Vol 133 (4) ◽  
pp. 999-1007
Author(s):  
R G Gregerson ◽  
L Cameron ◽  
M McLean ◽  
P Dennis ◽  
J Strommer
Keyword(s):  
Chromosomal Location ◽  
Higher Plants ◽  
Gene Encoding ◽  
Genomic Libraries ◽  
Regulatory Strategy ◽  
Adh1 Gene ◽  
Adh Genes ◽  
Genes Encoding ◽  
Adh Gene ◽  
Polymerase Chain

Abstract In most higher plants the genes encoding alcohol dehydrogenase comprise a small gene family, usually with two members. The Adh1 gene of Petunia has been cloned and analyzed, but a second identifiable gene was not recovered from any of three genomic libraries. We have therefore employed the polymerase chain reaction to obtain the major portion of a second Adh gene. From sequence, mapping and northern data we conclude this gene encodes ADH2, the major anaerobically inducible Adh gene of Petunia. The availability of both Adh1 and Adh2 from Petunia has permitted us to compare their structures and patterns of expression to those of the well-studied Adh genes of maize, of which one is highly expressed developmentally, while both are induced in response to hypoxia. Despite their evolutionary distance, evidenced by deduced amino acid sequence as well as taxonomic classification, the pairs of genes are regulated in strikingly similar ways in maize and Petunia. Our findings suggest a significant biological basis for the regulatory strategy employed by these distant species for differential expression of multiple Adh genes.

scholarly journals Characterization of the genomic structure, chromosomal location, promoter, and development expression of the alpha-globin transcription factor CP2

1994 ◽  
Vol 269 (15) ◽  
pp. 11663-11671
Author(s):  
S.L. Swendeman ◽  
C. Spielholz ◽  
N.A. Jenkins ◽  
D.J. Gilbert ◽  
N.G. Copeland ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Chromosomal Location ◽  
Genomic Structure ◽  
Alpha Globin

scholarly journals Differential activation mechanisms of two isoforms of Gcr1 transcription factor generated from spliced and un-spliced transcripts in Saccharomyces cerevisiae

2020 ◽  
Author(s):  
Seungwoo Cha ◽  
Chang Pyo Hong ◽  
Hyun Ah Kang ◽  
Ji-Sook Hahn
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Transcription Factor ◽  
Target Genes ◽  
Gene Encoding ◽  
Metabolic Switch ◽  
Differential Activation ◽  
N Terminus ◽  
Activation Mechanisms ◽  
In Trans ◽  
Separate Activation

Abstract Gcr1, an important transcription factor for glycolytic genes in Saccharomyces cerevisiae, was recently revealed to have two isoforms, Gcr1U and Gcr1S, produced from un-spliced and spliced transcripts, respectively. In this study, by generating strains expressing only Gcr1U or Gcr1S using the CRISPR/Cas9 system, we elucidate differential activation mechanisms of these two isoforms. The Gcr1U monomer forms an active complex with its coactivator Gcr2 homodimer, whereas Gcr1S acts as a homodimer without Gcr2. The USS domain, 55 residues at the N-terminus existing only in Gcr1U, inhibits dimerization of Gcr1U and even acts in trans to inhibit Gcr1S dimerization. The Gcr1S monomer inhibits the metabolic switch from fermentation to respiration by directly binding to the ALD4 promoter, which can be restored by overexpression of the ALD4 gene, encoding a mitochondrial aldehyde dehydrogenase required for ethanol utilization. Gcr1U and Gcr1S regulate almost the same target genes, but show unique activities depending on growth phase, suggesting that these isoforms play differential roles through separate activation mechanisms depending on environmental conditions.

scholarly journals Induction of transcription factor AP-1 by adenovirus E1A protein and cAMP.

1989 ◽  
Vol 3 (12a) ◽  
pp. 1991-2002 ◽  
Author(s):  
U Muller ◽  
M P Roberts ◽  
D A Engel ◽  
W Doerfler ◽  
T Shenk
Keyword(s):  
Transcription Factor ◽  
Adenovirus E1a ◽  
E1a Protein

scholarly journals Cloning, Tissue Expression, and Chromosomal Location of the Mouse Insulin Receptor Substrate 4 Gene*

Endocrinology ◽  
1999 ◽  
Vol 140 (3) ◽  
pp. 1329-1337 ◽  
Author(s):  
Valeria R. Fantin ◽  
Brian E. Lavan ◽  
Qing Wang ◽  
Nancy A. Jenkins ◽  
Debra J. Gilbert ◽  
...  
Keyword(s):  
Insulin Receptor ◽  
Chromosomal Location ◽  
Tissue Expression ◽  
Insulin Receptor Substrate

Cloning of the canine gene encoding transcription factor Pit-1 and its exclusion as candidate gene in a canine model of pituitary dwarfism

2000 ◽  
Vol 11 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Irma S. Lantinga-van Leeuwen ◽  
Jan A. Mol ◽  
Hans S. Kooistra ◽  
Ad Rijnberk ◽  
Matthew Breen ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Candidate Gene ◽  
Canine Model ◽  
Gene Encoding ◽  
Pituitary Dwarfism

scholarly journals Biochemical and Molecular Analysis of Pink Tomatoes: Deregulated Expression of the Gene Encoding Transcription Factor SlMYB12 Leads to Pink Tomato Fruit Color

2009 ◽  
Vol 152 (1) ◽  
pp. 71-84 ◽  
Author(s):  
Ana-Rosa Ballester ◽  
Jos Molthoff ◽  
Ric de Vos ◽  
Bas te Lintel Hekkert ◽  
Diego Orzaez ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Molecular Analysis ◽  
Tomato Fruit ◽  
Fruit Color ◽  
Gene Encoding
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