The linkage map of sheep Chromosome 6 compared with orthologous regions in other species

1996 ◽  
Vol 7 (5) ◽  
pp. 373-376 ◽  
Author(s):  
E. A. Lord ◽  
J. M. Lumsden ◽  
K. G. Dodds ◽  
H. M. Henry ◽  
A. M. Crawford ◽  
...  
Keyword(s):  
Linkage Map ◽  
Chromosome 6 ◽  
Sheep Chromosome

Characterisation and mapping of the Booroola (FecB) gene using regression analysis in sheep

2000 ◽  
Vol 2000 ◽  
pp. 41-41
Author(s):  
G.A. Walling ◽  
K.G. Dodds ◽  
S.M. Galloway ◽  
A.E. Beattie ◽  
E.A. Lord ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Linkage Analysis ◽  
Ovulation Rate ◽  
Chromosome 6 ◽  
Female Progeny ◽  
Gene Effect ◽  
Sheep Chromosome ◽  
Genotype Assignment ◽  
Constant Gene ◽  
Breeding Seasons

The Booroola Merino strain of sheep carries a major autosomal mutation (FecB) which increases ovulation rate (Davis et al., 1982). To map the gene, heterozygous sires (B+) were mated to non-carrier ewes (++). The female progeny were then examined by laproscopy to determine ovulation rates and these phenotypes used to assign progeny genotypes (B+, ++ or undetermined). Linkage analysis between the assigned Booroola genotype and a set of marker genotypes was used to assign the Booroola gene to a region of sheep chromosome 6 (OOV6) (Montgomery et al., 1994). These studies relied on accurate genotype assignment and a constant gene effect across animals and breeding seasons. This study aims to use regression analysis to verify the validity of these assumptions.

The consequences of carrying the Booroola fecundity (FecB) gene on sheep liveweight

2000 ◽  
Vol 2000 ◽  
pp. 43-43 ◽  
Author(s):  
G.A. Walling ◽  
K.G. Dodds ◽  
S.M. Galloway ◽  
A.E. Beattie ◽  
E.A. Lord ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Quantitative Trait ◽  
Personal Communication ◽  
Pleiotropic Effect ◽  
Ovulation Rate ◽  
Chromosome 6 ◽  
Sheep Chromosome ◽  
Trait Locus ◽  
Fertility Traits

The increase in ovulation rate caused by the Booroola gene was first observed in the Booroola Merino strain of sheep (Davis et al., 1982) and the gene was subsequently mapped to sheep chromosome 6 (OOV6) (Montgomery et al. 1994). The low heritability of fertility traits and the desire to produce more lambs per ewe from meat breeds has lead to many crossbreeding programs seeking to obtain the benefits of the Booroola gene. However, many producers report animals carrying a Booroola allele to be lighter than non-carriers (G. Davis, personal communication). The Booroola Merino strain of sheep is typically lighter than recipient breeds used in the introgression programmes e.g. Romney. This study aims to determine whether the Booroola gene has a pleiotropic effect on liveweight or whether there is any evidence to suggest a closely linked quantitative trait locus (QTL) affecting liveweight that may ‘hitchhike’ with the Booroola gene.

A linkage map of Sheep Chromosome X (OARX) aligned to Human Chromosome X (HSAX)

2010 ◽  
Vol 42 (3) ◽  
pp. 321-324
Author(s):  
M. C. French ◽  
K. G. Dodds ◽  
G. H. Davis ◽  
S. M. Galloway ◽  
S. J. Edwards
Keyword(s):  
Human Chromosome ◽  
Linkage Map ◽  
Chromosome X ◽  
Sheep Chromosome

A Linkage Map of Chromosome 6 Based on 2 Large Kindreds Segregating Bipolar Affective Disorder

DNA Sequence ◽  
1997 ◽  
Vol 8 (3) ◽  
pp. 143-146 ◽  
Author(s):  
D. S. Gerhard ◽  
M. C. Labuda ◽  
D. Marshall ◽  
K. Otten ◽  
T. Reich ◽  
...  
Keyword(s):  
Linkage Map ◽  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Chromosome 6

Seven loci on human Chromosome 4 map onto sheep Chromosome 6: a proposal to restore the original nomenclature of this sheep chromosome

1994 ◽  
Vol 5 (7) ◽  
pp. 429-433 ◽  
Author(s):  
T. E. Broad ◽  
D. J. Burkin ◽  
L. M. Cambridge ◽  
D. W. Maher ◽  
P. E. Lewis ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Chromosome 6 ◽  
Chromosome 4 ◽  
Sheep Chromosome ◽  
Human Chromosome 4

scholarly journals Integration of the classical and molecular linkage maps of tomato chromosome 6.

Genetics ◽  
1993 ◽  
Vol 135 (4) ◽  
pp. 1175-1186
Author(s):  
R Weide ◽  
M F van Wordragen ◽  
R K Lankhorst ◽  
R Verkerk ◽  
C Hanhart ◽  
...  
Keyword(s):  
Linkage Map ◽  
Rapd Markers ◽  
Linkage Data ◽  
Chromosome 6 ◽  
Morphological Markers ◽  
Limited Information ◽  
Tomato Genome ◽  
The Past ◽  
Molecular Linkage Map ◽  
Tomato Chromosome

Abstract In the past, a classical map of the tomato genome has been established that is based on linkage data from intraspecific Lycopersicon esculentum crosses. In addition, a high density molecular linkage map has recently been constructed using a L. esculentum x L. pennellii cross. As the respective maps only partially match, they provide limited information about the relative positions of classical and molecular markers. In this paper we describe the construction of an integrated linkage map of tomato chromosome 6 that shows the position of cDNA-, genomic DNA- and RAPD markers relative to 10 classical markers. Integration was achieved by using a L. esculentum line containing an introgressed chromosome 6 from L. pennellii in crosses to a variety of L. esculentum marker lines. In addition, an improved version of the classical linkage map is presented that is based on a combined analysis of new linkage data for 16 morphological markers and literature data. Unlike the classical map currently in use, the revised map reveals clustering of markers into three major groups around the yv, m-2 and c loci, respectively. Although crossing-over rates are clearly different when comparing intraspecific L. esculentum crosses with L. esculentum x L. pennellii crosses, the clusters of morphological markers on the classical map coincide with clusters of genomic- and cDNA-markers on the molecular map constructed by Tanksley and coworkers.

The Booroola Fecundity (FecB) Gene Maps to Sheep Chromosome 6

Genomics ◽  
1994 ◽  
Vol 22 (1) ◽  
pp. 148-153 ◽  
Author(s):  
Grant W. Montgomery ◽  
Eric A. Lord ◽  
Joanne M. Penty ◽  
Ken G. Dodds ◽  
Tom E. Broad ◽  
...  
Keyword(s):  
Chromosome 6 ◽  
Sheep Chromosome ◽  
Gene Maps

The application of AFLP fingerprinting to construct a YAC contig containing ADH2 and MTP on sheep chromosome 6

1999 ◽  
Vol 84 (3-4) ◽  
pp. 225-229 ◽  
Author(s):  
J.M. Lumsden ◽  
E.A. Lord ◽  
S.A. Cato ◽  
T.E. Richardson ◽  
T.C. van Stijn ◽  
...  
Keyword(s):  
Chromosome 6 ◽  
Aflp Fingerprinting ◽  
Sheep Chromosome ◽  
Yac Contig

The gonadotrophin-releasing hormone receptor maps to sheep Chromosome 6 outside of the region of the FecB locus

1995 ◽  
Vol 6 (6) ◽  
pp. 436-438 ◽  
Author(s):  
G. W. Montgomery ◽  
J. M. Penty ◽  
E. A. Lord ◽  
J. Brooks ◽  
A. S. McNeilly
Keyword(s):  
Hormone Receptor ◽  
Chromosome 6 ◽  
Releasing Hormone ◽  
Sheep Chromosome ◽  
Gonadotrophin Releasing Hormone
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