Seven loci on human Chromosome 4 map onto sheep Chromosome 6: a proposal to restore the original nomenclature of this sheep chromosome

1994 ◽  
Vol 5 (7) ◽  
pp. 429-433 ◽  
Author(s):  
T. E. Broad ◽  
D. J. Burkin ◽  
L. M. Cambridge ◽  
D. W. Maher ◽  
P. E. Lewis ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Chromosome 6 ◽  
Chromosome 4 ◽  
Sheep Chromosome ◽  
Human Chromosome 4

scholarly journals Mapping of dentin-specific acidic phosphoprotein and integrin-binding sialoprotein in sheep defines an inversion breakpoint with respect to human chromosome 4Q

1999 ◽  
Vol 22 (1) ◽  
pp. 29-31 ◽  
Author(s):  
Joanne M. Lumsden ◽  
Eric A. Lord ◽  
Karen L. Hirst ◽  
Michael J. Dixon ◽  
Grant W. Montgomery
Keyword(s):  
Human Chromosome ◽  
Linkage Map ◽  
Gene Order ◽  
Breakpoint Region ◽  
Rflp Markers ◽  
Chromosome 6 ◽  
Chromosome 4 ◽  
Human Chromosome 4 ◽  
Yac Contig ◽  
Secreted Phosphoprotein 1

Genes from sheep chromosome 6 map to human chromosome 4 in the region extending from 4p16 to 4q26. However, there is an inversion of gene order in the central portion of the chromosome with one breakpoint close to secreted phosphoprotein 1 (SPP1). Genes for SPP1, integrin-binding sialoprotein (IBSP) and dentin-specific acidic phosphoprotein (DMP1) are located close together in a YAC contig in the human. RFLP markers were developed for DMP1 and IBSP in sheep and located on the sheep linkage map to further define the breakpoint region. There were no recombinants between SPP1 and IBSP indicating that these loci are close together in sheep, as in humans. DMP1 was located approximately 80 cM from SPP1 in sheep, 7 cM from the microsatellite BMC4203. In the human YAC contig, the order of these genes is SPP1-IBSP-DMP1 with 340 kb separating SPP1 and IBSP and 150 kb between IBSP and DMP1. Therefore, one breakpoint for the inversion in gene order between the sheep and the human has been narrowed to a region of 150 kb on the human map.

Generation and characterization of irradiation hybrids of human chromosome 4

1991 ◽  
Vol 17 (5) ◽  
pp. 471-480 ◽  
Author(s):  
Lynn A. Doucette-Stamm ◽  
Laura Riba ◽  
Barbara Handelin ◽  
Michael Difilippantonio ◽  
David C. Ward ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Chromosome 4 ◽  
Human Chromosome 4

Breakpoint analysis of the pericentric inversion distinguishing human chromosome 4 from the homologous chromosome in the chimpanzee (Pan troglodytes)

2004 ◽  
Vol 25 (1) ◽  
pp. 45-55 ◽  
Author(s):  
Hildegard Kehrer-Sawatzki ◽  
Catharina Sandig ◽  
Nadia Chuzhanova ◽  
Violaine Goidts ◽  
Justyna M. Szamalek ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Pan Troglodytes ◽  
Pericentric Inversion ◽  
Homologous Chromosome ◽  
Chromosome 4 ◽  
Breakpoint Analysis ◽  
Human Chromosome 4

Interleukin 2 (IL2) is assigned to human chromosome 4

1984 ◽  
Vol 10 (3) ◽  
pp. 315-318 ◽  
Author(s):  
T. Shows ◽  
R. Eddy ◽  
L. Haley ◽  
M. Byers ◽  
M. Henry ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Interleukin 2 ◽  
Chromosome 4 ◽  
Human Chromosome 4

Construction of cosmid contigs and high-resolution restriction mapping of the Huntington disease region of human chromosome 4

1993 ◽  
Vol 2 (7) ◽  
pp. 889-899 ◽  
Author(s):  
Jlan Zuo ◽  
Carolyn Robblns ◽  
Slamak Bahariloo ◽  
David R. Cox ◽  
Richard M. Myers
Keyword(s):  
High Resolution ◽  
Human Chromosome ◽  
Huntington Disease ◽  
Restriction Mapping ◽  
Chromosome 4 ◽  
Human Chromosome 4 ◽  
Disease Region ◽  
Cosmid Contigs

Isolation of yeast artificial chromosome clones from 54 polymorphic loci mapped with high odds on human chromosome 4

1994 ◽  
Vol 3 (2) ◽  
pp. 243-246 ◽  
Author(s):  
Jlan-Bing Fan ◽  
Joe DeYoung ◽  
Rob Lagacé ◽  
R.Andrea Lina ◽  
Zhldong Xu ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Yeast Artificial Chromosome ◽  
Artificial Chromosome ◽  
Chromosome 4 ◽  
High Odds ◽  
Polymorphic Loci ◽  
Human Chromosome 4
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