Extracellular matrix surface network of embryogenic units of friable maize callus contains arabinogalactan-proteins recognized by monoclonal antibody JIM4

1999 ◽  
Vol 18 (5) ◽  
pp. 369-374 ◽  
Author(s):  
J. Šamaj ◽  
F. Baluška ◽  
M. Bobák ◽  
D. Volkmann
Keyword(s):  
Monoclonal Antibody ◽  
Extracellular Matrix ◽  
Arabinogalactan Proteins ◽  
Matrix Surface ◽  
Surface Network ◽  
Maize Callus

scholarly journals Extracellular matrix surface network is associated with non-morphogenic calli of Helianthus tuberosus cv. Albik produced from various explants

2014 ◽  
Vol 83 (1) ◽  
pp. 67-73 ◽  
Author(s):  
Maria Pilarska ◽  
Marzena Popielarska-Konieczna ◽  
Halina Ślesak ◽  
Małgorzata Kozieradzka-Kiszkurno ◽  
Grzegorz Góralski ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
In Vitro Regeneration ◽  
Vascular Bundles ◽  
Helianthus Tuberosus ◽  
Important Species ◽  
Electron Microscopies ◽  
Transmission Electron ◽  
Matrix Surface ◽  
Surface Network

<em>Helianthus tuberosus</em> is economically important species. To improve characters of this energetic plant via genetic modification, production of callus tissue and plant regeneration are the first steps. A new, potentially energetic cultivar Albik was used in this study to test callus induction and regeneration. Callus was produced on leaves, petioles, apical meristems and stems from field-harvested plants but was totally non-morphogenic. Its induction started in the cortex and vascular bundles as confirmed by histological analysis. The surface of heterogeneous callus was partially covered with a membranous extracellular matrix surface network visible in scanning and transmission electron microscopies. The results clearly indicate that: (<strong><em>i</em></strong>) the morphogenic capacity of callus in topinambur is genotype dependent, (<strong><em>ii</em></strong>) cv. Albik of <em>H. tuberosus</em> proved recalcitrant in in vitro regeneration, and (<strong><em>iii</em></strong>) extracellular matrix surface network is not a morphogenic marker in this cultivar.

scholarly journals Are extracellular matrix surface network components involved in signalling and protective function?

2008 ◽  
Vol 3 (9) ◽  
pp. 707-709 ◽  
Author(s):  
Marzena Popielarska-Konieczna ◽  
Małgorzata Kozieradzka-Kiszkurno ◽  
Joanna Świerczyńska ◽  
Grzegorz Góralski ◽  
Halina Ślesak ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Protective Function ◽  
Matrix Surface ◽  
Surface Network

Ultrastructure and histochemical analysis of extracellular matrix surface network in kiwifruit endosperm-derived callus culture

2008 ◽  
Vol 27 (7) ◽  
pp. 1137-1145 ◽  
Author(s):  
M. Popielarska-Konieczna ◽  
M. Kozieradzka-Kiszkurno ◽  
J. Świerczyńska ◽  
G. Góralski ◽  
H. Ślesak ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Callus Culture ◽  
Histochemical Analysis ◽  
Matrix Surface ◽  
Surface Network

Extracellular Matrix Surface Network During Plant Regeneration in Wheat Anther Culture

2005 ◽  
Vol 83 (2) ◽  
pp. 201-208 ◽  
Author(s):  
R. Konieczny ◽  
J. Bohdanowicz ◽  
A.Z. Czaplicki ◽  
L. Przywara
Keyword(s):  
Extracellular Matrix ◽  
Plant Regeneration ◽  
Anther Culture ◽  
Matrix Surface ◽  
Surface Network

An overview of the α4β1 integrin and the potential therapeutic role of its antagonists

2021 ◽  
Vol 28 ◽  
Author(s):  
Elenilze F. B. Ferreira ◽  
Luciane B. Silva ◽  
Josiane V. Cruz ◽  
Pedro H. F. Araújo ◽  
Njogu M. Kimani ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Monoclonal Antibody ◽  
Extracellular Matrix ◽  
Inflammatory Responses ◽  
Cellular Responses ◽  
Tumour Invasion ◽  
Potential Therapeutic Role ◽  
Integrin Antagonists ◽  
Inside Out

: This article presents a simplified view of integrins with emphasis on the α4 (α4β1/VLA-4) integrin. Integrins are heterodimeric proteins expressed on the cell surface of leukocytes that participate in a wide variety of functions, such as survival, growth, differentiation, migration, inflammatory responses, tumour invasion, among others. When the extracellular matrix is degraded or deformed, cells are forced to undergo responsive changes that influence remodelling during physiological and pathological events. Integrins recognize these changes and trigger a series of cellular responses, forming a physical connection between the interior and the outside of the cell. The communication of integrins through the plasma membrane occurs in both directions, from the extracellular to the intracellular (outside-in) and from the intracellular to the extracellular (inside-out). Integrins are valid targets for antibodies and small molecule antagonists. One example is the monoclonal antibody natalizumab, marketed under the name of TYSABRI®, used in the treatment of recurrent multiple sclerosis, which inhibits the adhesion of α4 integrin to its counter-receptor. α4β1 Integrin antagonists are summarized here and their utility as therapeutics discussed.

A fusion protein N-cadherin-Fc as an artificial extracellular matrix surface for maintenance of stem cell features

Biomaterials ◽  
2010 ◽  
Vol 31 (20) ◽  
pp. 5287-5296 ◽  
Author(s):  
Xiao-Shan Yue ◽  
Yuta Murakami ◽  
Toshiyuki Tamai ◽  
Masato Nagaoka ◽  
Chong-Su Cho ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Stem Cell ◽  
Fusion Protein ◽  
Matrix Surface ◽  
Artificial Extracellular Matrix
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