Characterization of the amyR gene encoding a transcriptional activator for the amylase genes in Aspergillus nidulans

2001 ◽  
Vol 39 (1) ◽  
pp. 10-15 ◽  
Author(s):  
Shuji Tani ◽  
Yoko Katsuyama ◽  
Tomoko Hayashi ◽  
Hayato Suzuki ◽  
Masashi Kato ◽  
...  
1997 ◽  
Vol 31 (4) ◽  
pp. 348-356 ◽  
Author(s):  
Jacek Topczewski ◽  
Marzena Sienko ◽  
A. Paszewski

Gene ◽  
1999 ◽  
Vol 236 (2) ◽  
pp. 293-301 ◽  
Author(s):  
Kil-Hwan Kim ◽  
Tomohiro Akashi ◽  
Ikuyo Mizuguchi ◽  
Akihiko Kikuchi

2006 ◽  
Vol 5 (8) ◽  
pp. 1441-1445 ◽  
Author(s):  
Márcia Eliana da Silva Ferreira ◽  
Marcela Savoldi ◽  
Pierina Sueli Bonato ◽  
Maria Helena S. Goldman ◽  
Gustavo H. Goldman

ABSTRACT Mutations in the human HPD gene (encoding 4-hydroxyphenylpyruvic acid dioxygenase) cause hereditary tyrosinemia type 3 (HT3). We deleted the Aspergillus nidulans homologue (hpdA). We showed that the mutant strain is not able to grow in the presence of phenylalanine and that it accumulates increased concentrations of tyrosine and 4-hydroxyphenylpyruvic acid, mimicking the human HT3 phenotype.


2005 ◽  
Vol 42 (7) ◽  
pp. 590-600 ◽  
Author(s):  
Chang-Jun Choi ◽  
Hee-Jeong Ju ◽  
Byung-Hyun Park ◽  
Rui Qin ◽  
Kwang-Yeop Jahng ◽  
...  

Genetics ◽  
1989 ◽  
Vol 121 (2) ◽  
pp. 249-254 ◽  
Author(s):  
E B O'Hara ◽  
W E Timberlake

Abstract We investigated the molecular organization of the region of Aspergillus nidulans chromosome I containing yA, a gene encoding the developmentally regulated enzyme conidial laccase. DNA fragments were identified that complemented the yA2 mutation and were shown to correspond to yA by genetic mapping and gene disruption experiments. The molecular map of the region was oriented to the genetic map by testing DNA fragments for their ability to complement a mutation in the tightly linked adE gene. The yA gene codes for a 2200 nucleotide mRNA that is present at low levels in vegetative cells and mature conidia, but accumulates to high levels in sporulating cultures. yA mRNA appears shortly after differentiation of sporogenous phialide cells. It accumulates in two developmentally abnormal mutant strains that produce phialides but is absent from two mutant strains that do not produce phialides. Thus, yA transcription is probably restricted to phialides. This result is discussed in relationship to the physiological roles played by phialides in spore differentiation.


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