scholarly journals Fungal Metabolic Model for Tyrosinemia Type 3: Molecular Characterization of a Gene Encoding a 4-Hydroxy-Phenyl Pyruvate Dioxygenase from Aspergillus nidulans

2006 ◽  
Vol 5 (8) ◽  
pp. 1441-1445 ◽  
Author(s):  
Márcia Eliana da Silva Ferreira ◽  
Marcela Savoldi ◽  
Pierina Sueli Bonato ◽  
Maria Helena S. Goldman ◽  
Gustavo H. Goldman
Keyword(s):  
Aspergillus Nidulans ◽  
Molecular Characterization ◽  
Mutant Strain ◽  
Metabolic Model ◽  
Gene Encoding ◽  
Hereditary Tyrosinemia ◽  
Type 3

ABSTRACT Mutations in the human HPD gene (encoding 4-hydroxyphenylpyruvic acid dioxygenase) cause hereditary tyrosinemia type 3 (HT3). We deleted the Aspergillus nidulans homologue (hpdA). We showed that the mutant strain is not able to grow in the presence of phenylalanine and that it accumulates increased concentrations of tyrosine and 4-hydroxyphenylpyruvic acid, mimicking the human HT3 phenotype.

scholarly journals Molecular Characterization of the Gene Encoding a New AmpC β-Lactamase in a Clinical Strain of Acinetobacter Genomic Species 3

2004 ◽  
Vol 48 (4) ◽  
pp. 1374-1378 ◽  
Author(s):  
Alejandro Beceiro ◽  
Lourdes Dominguez ◽  
Anna Ribera ◽  
Jordi Vila ◽  
Francisca Molina ◽  
...  
Keyword(s):  
Nucleotide Sequence ◽  
Molecular Characterization ◽  
Biochemical Properties ◽  
Clinical Strain ◽  
The Novel ◽  
Gene Encoding ◽  
Genomic Species ◽  
First Time

ABSTRACT A presumptive chromosomal cephalosporinase (pI, 9.0) from a clinical strain of Acinetobacter genomic species 3 (AG3) is reported. The nucleotide sequence of this β-lactamase shows for the first time the gene encoding an AmpC enzyme in AG3. In addition, the biochemical properties of the novel AG3 AmpC β-lactamase are reported

Molecular characterization of Streptococcus mutans strains containing the cnm gene encoding a collagen-binding adhesin

2010 ◽  
Vol 55 (1) ◽  
pp. 34-39 ◽  
Author(s):  
K. Nakano ◽  
R. Nomura ◽  
N. Taniguchi ◽  
J. Lapirattanakul ◽  
A. Kojima ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Streptococcus Mutans ◽  
Gene Encoding ◽  
Collagen Binding

Molecular characterization of a phloem-specific gene encoding the filament protein, Phloem Protein 1 (PP1), from Cucurbita maxima

1997 ◽  
Vol 12 (1) ◽  
pp. 49-61 ◽  
Author(s):  
Anna M. Clark ◽  
Karin R. Jacobsen ◽  
Dwight E. Bostwick ◽  
Joanne M. Dannenhoffer ◽  
Megan I. Skaggs ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Specific Gene ◽  
Cucurbita Maxima ◽  
Gene Encoding ◽  
Phloem Protein ◽  
Filament Protein

Molecular Characterization of Transforming Growth Factor Type ?3

1990 ◽  
Vol 593 (1 Transforming) ◽  
pp. 26-42 ◽  
Author(s):  
PETER DIJKE ◽  
KENNETH K. IWATA ◽  
MIDORY THORIKAY ◽  
JANINE SCHWEDES ◽  
ALEXANDER STEWART ◽  
...  
Keyword(s):  
Growth Factor ◽  
Molecular Characterization ◽  
Transforming Growth Factor ◽  
Factor Type ◽  
Type 3
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