p53 serum antibodies as prognostic indicator in head and neck cancer

1997 ◽  
Vol 44 (2) ◽  
pp. 112-116 ◽  
Author(s):  
J. A. Werner ◽  
Stefan Gottschlich ◽  
Benedikt J. Folz ◽  
Tibor Goeroegh ◽  
Burkard M. Lippert ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Prognostic Indicator ◽  
Serum Antibodies

scholarly journals Neutrophil-to-lymphocyte ratio as a prognostic indicator in head and neck cancer: A systematic review and meta-analysis

Head & Neck ◽  
2018 ◽  
Vol 40 (11) ◽  
pp. 2546-2557 ◽  
Author(s):  
Tristan Tham ◽  
Yonatan Bardash ◽  
Saori Wendy Herman ◽  
Peter David Costantino
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Prognostic Indicator ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio

Nutritional Status-a Prognostic Indicator in Head and Neck Cancer

1985 ◽  
Vol 93 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Gerald B. Brookes
Keyword(s):  
Head And Neck Cancer ◽  
Nutritional Status ◽  
Head And Neck ◽  
Neck Cancer ◽  
Prognostic Indicator ◽  
Nutritional Deficit ◽  
Significant Difference ◽  
Table Analysis ◽  
A Prospective Study ◽  
Index Estimation

A prospective study into the nutritional status of 114 patients with untreated primary squamous cell carcinoma of the head and neck was undertaken to assess its possible prognostic value for survival. Nutritional status was evaluated by anthropometry, creatinine height index estimation, serum albumin and transferrin assays, and nitrogen balance studies. Weight change and other anthropometric indices found to be the most reliable nutritional parameters were averaged to derive a clinically useful, general nutritional status score. A nutritional deficit was found in 43 of the 114 patients (37.7%) and was associated with neoplasms of the upper gastrointestinal tract in more than 80% of the patients. Life table analysis showed a statistically very highly significant difference between the survival of the adequately nourished patients (57.5% at 2 years) and the survival of the undernourished patients (7.5% at 2 years) (χ2 = 36.08; P = .0). These results indicate that nutritional deficiency is an important adverse prognostic factor in head and neck cancer. Undernutrition probably exerts its effect, at least in part, by causing secondary immunologic dysfunction.

Interleukin-2 Release from Lymphocytes of Patients with Head and Neck Cancer

1989 ◽  
Vol 98 (3) ◽  
pp. 179-184 ◽  
Author(s):  
Thomas P. U. Wustrow ◽  
Dieter Kabelitz
Keyword(s):  
Head And Neck Cancer ◽  
T Cell ◽  
Head And Neck ◽  
Neck Cancer ◽  
Interleukin 2 ◽  
Prognostic Indicator ◽  
Cytotoxic T Cell ◽  
Patients With Cancer ◽  
Control Subjects

Interleukin-2 (IL-2) plays a central role in cellular immune regulation. In vitro this cytokine is secreted after mitogenic stimulation with phorbolester (PMA), phytohemagglutinin A (PHA), or the monoclonal T cell antibody OKT3. In our experiments the IL-2 concentration was measured in a biologic system using an IL-2-dependent murine cytotoxic T cell line. Control subjects who were age-matched to patients with head and neck cancers did not show an altered IL-2 production in vitro, irrespective of whether they were accustomed to high alcohol consumption or cigarette smoking. Patients with cancer of the larynx did not differ significantly from control subjects. Most prominent was the significant reduction in IL-2 release of patients with cancer of the oropharynx and in patients with positive lymph nodes in the neck. Impaired IL-2 secretion in head and neck cancer patients may therefore be an additional prognostic indicator worthy of further investigation.

scholarly journals Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer

2011 ◽  
Vol 104 (12) ◽  
pp. 1896-1905 ◽  
Author(s):  
K S Anderson ◽  
J Wong ◽  
G D'Souza ◽  
A B Riemer ◽  
J Lorch ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Serum Antibodies

The lymphocyte-to-monocyte ratio as a prognostic indicator in head and neck cancer: a systematic review and meta-analysis

2018 ◽  
Vol 275 (7) ◽  
pp. 1663-1670 ◽  
Author(s):  
Tristan Tham ◽  
Caitlin Olson ◽  
Julian Khaymovich ◽  
Saori Wendy Herman ◽  
Peter David Costantino
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Prognostic Indicator ◽  
Lymphocyte To Monocyte Ratio

T-Lymphocytes as a Prognostic Indicator in Head and Neck Cancer

1986 ◽  
Vol 112 (9) ◽  
pp. 938-941 ◽  
Author(s):  
D. E. Schuller ◽  
R. P. Rock ◽  
J. J. Rinehart ◽  
A. R. Koolemans-Beynen
Keyword(s):  
Head And Neck Cancer ◽  
T Lymphocytes ◽  
Head And Neck ◽  
Neck Cancer ◽  
Prognostic Indicator
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