Characteristics of a new fully programmable blood sampling device for monitoring blood radioactivity during PET

2000 ◽  
Vol 28 (1) ◽  
pp. 81-89 ◽  
Author(s):  
Ronald Boellaard ◽  
Arthur van Lingen ◽  
Suzette C.M. van Balen ◽  
Bas G. Hoving ◽  
Adriaan A. Lammertsma
Keyword(s):  
Blood Sampling ◽  
Sampling Device ◽  
Blood Radioactivity

Design and modeling of microneedle integrated with microactuator for drug delivery

2014 ◽  
Vol 03 (03) ◽  
pp. 1450016
Author(s):  
K. Girija Sravani ◽  
Y. Srinivas ◽  
Bikash Swain ◽  
K. Sunil Banu ◽  
K. Srinivasa Rao
Keyword(s):  
Drug Delivery ◽  
Piezoelectric Actuator ◽  
Dimensional Stability ◽  
Blood Sampling ◽  
High Dimensional ◽  
Sampling Device ◽  
Metal Electrodes ◽  
New Model ◽  
Space Requirements ◽  
Manufacturing Time

Today's world has very much demand for the development of microscale devices, due to its less cost, space requirements, high-dimensional stability and especially manufacturing time. In this paper, we have design and simulated MEMS based microactuator and microneedle integration which will be very helpful for blood sampling device like e-mosquito. The dimensions of the modeled beam are of 100 mm long, 30 mm width, 10 mm thickness. This new design model consists of piezoceramic material sandwiched between two metal electrodes and the piezoelectric actuator is made with microneedle which will help for blood sampling purposes. The results after the simulation of this new model present that it will be suitable for blood sampling analysis with aluminum as electrodes and silicon as microneedle.

scholarly journals Evaluation of New Arterial Line System Kits with Blood-Sampling Device.

1999 ◽  
Vol 19 (2) ◽  
pp. 152-156
Author(s):  
Tomomichi KOGA ◽  
Michiyoshi SANUKI ◽  
Hiroyuki KINOSHITA ◽  
Kouji MIYASYOU ◽  
Shigeaki KURITA
Keyword(s):  
Blood Sampling ◽  
Arterial Line ◽  
Sampling Device ◽  
Line System

Implantable device for drug delivery and blood sampling in the rat

1985 ◽  
Vol 59 (5) ◽  
pp. 1665-1666
Author(s):  
J. F. Chester ◽  
S. A. Weitzman ◽  
R. A. Malt
Keyword(s):  
Drug Delivery ◽  
Polyvinyl Chloride ◽  
Implantable Device ◽  
Blood Sampling ◽  
Venous Sampling ◽  
Intravenous Catheter ◽  
Right Colon ◽  
Sampling Device ◽  
The Right

An implantable drug-delivery and venous sampling device is described that is constructed from a polyvinyl chloride catheter and a rubber intravenous catheter plug coated with Silastic. The implant was used for repeated venous sampling and for both administration of parenteral solutions and injections into the right colon of the rat for periods to 1 mo.

scholarly journals Changes in Plasma Tryptophan and Melatonin Content in Penned Sheep

1978 ◽  
Vol 31 (1) ◽  
pp. 49
Author(s):  
DJ Kennaway ◽  
KJ Porter ◽  
RF Seamark
Keyword(s):  
Circadian Rhythms ◽  
Plasma Levels ◽  
Blood Sampling ◽  
Night Time ◽  
Sampling Device ◽  
Blood Constituents ◽  
Circadian Changes ◽  
Plasma Tryptophan ◽  
Tryptophan Content ◽  
The Relationship

The present study was undertaken to examine the relationship between the plasma levels of melatonin and its precursor tryptophan. No circadian changes in plasma total tryptophan content were evident which could be related to the marked night-time rise in plasma melatonin. An automated programmable blood sampling device suited to studies of circadian rhythms in blood constituents is described.

Effects of magnesium on exercise performance and plasma glucose and lactate concentrations in rats using a novel blood-sampling technique

2009 ◽  
Vol 34 (6) ◽  
pp. 1040-1047 ◽  
Author(s):  
Ying-Ju Chen ◽  
Hsuan-Ying Chen ◽  
Ming-Fu Wang ◽  
Mei-Hsiang Hsu ◽  
Woei-Ming Liang ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Exercise Performance ◽  
Treadmill Exercise ◽  
Sampling Technique ◽  
Blood Sampling ◽  
Control Group ◽  
Sprague Dawley ◽  
Sampling Device ◽  
Blood Samples ◽  
Adequate Diet

Repeated blood sampling in rodents is often necessary and difficult. Magnesium has been touted as an agent for enhancing physical activity. An auto-blood-sampling device coupled with a microdialysis analyzer was developed to determine blood glucose and lactate concentrations in rats subjected to treadmill exercise. The effects of magnesium on exercise performance and blood energy metabolism were also evaluated. Sprague–Dawley rats fed a magnesium-adequate diet were randomly assigned to 2 experimental groups. Exercise performance was evaluated at 3 treadmill speeds (10, 15, and 20 m·min–1) with or without magnesium administration (90 mg·kg–1, intraperitoneal) in the first experiment. In the other experiment, each rat was fitted with a catheter in the jugular vein for collection of blood samples during the treadmill exercise at a speed of 20 m·min–1. Exercise performance was significantly higher at the lower speed of 10 m·min–1 in the control group. In addition, exercise performance was significantly enhanced only at 20 m·min–1 in the magnesium-sulfate-treated group when compared with the control group. Blood samples were collected every 15 min. Glucose concentrations increased significantly and then declined immediately after completion of the exercise task at 20 m·min–1 in both groups. However, glucose concentrations increased immediately after administration of magnesium and increased further during exercise when compared with those of the control group. Findings from a repeated blood-sampling assay suggest that increased blood glucose contributes to enhanced exercise performance by rats injected intraperitoneally with magnesium.

scholarly journals Impact of chronic catheterization and automated blood sampling (Accusampler) on serum corticosterone and fecal immunoreactive corticosterone metabolites and immunoglobulin A in male rats

2004 ◽  
Vol 180 (1) ◽  
pp. 145-153 ◽  
Author(s):  
F Royo ◽  
N Bjork ◽  
HE Carlsson ◽  
S Mayo ◽  
J Hau
Keyword(s):  
Diurnal Variation ◽  
Acute Stress ◽  
Immunoglobulin A ◽  
Blood Sampling ◽  
Male Rats ◽  
Sampling Device ◽  
Serum Corticosterone ◽  
Low Levels ◽  
Corticosterone Metabolites ◽  
Total Excretion

Jugular catheters were inserted in nine male rats under general isofluorane anesthesia and the catheters were connected to a commercially available computerized blood sampling device (Accusampler). Blood samples (150 microl) were collected every 4 h during the first 24 h after surgery and every 12 h during the following 72 h until 94 h after surgery, when the animals were killed. All fecal pellets were collected at blood sampling. Serum corticosterone and fecal concentrations of immunoreactive corticosterone metabolites and immunoglobulin A (IgA) were quantified by ELISAs. In blood, high corticosterone concentrations (>200 ng/ml) were recorded in the first samples obtained after surgery, but the concentrations decreased steadily during the day and became cyclical, showing a diurnal variation with high levels during evenings and low levels in the mornings. The automatic blood sampling itself did not result in recordable increases in serum corticosterone concentrations. The time delay between the presence of elevated corticosterone levels in blood and in feces was approximately 12 h. Fecal immunoreactive corticosterone metabolite levels remained elevated during the 94 h study period after surgery. The fecal concentrations of IgA showed substantial between-animal variation and decreased non-significantly after the surgery. Like serum corticosterone, fecal IgA showed a diurnal variation in amounts excreted, in this case with high values in the morning and low values in the evening. The concentrations of fecal corticosterone and IgA were negatively correlated in samples obtained before surgery but no correlation existed after surgery. This indicates that fecal immunoreactive corticosterone metabolites, but not IgA, constitute a good marker of acute stress. For immunoreactive corticosterone metabolites as well as for IgA, the concentration in feces correlated well with total excretion, making single fecal samplings usable as a measure of total secretion.

scholarly journals Consequences of the multipatient use of a single-patient capillary blood sampling device (CBSD)

2011 ◽  
Vol 5 (Suppl 6) ◽  
pp. P92
Author(s):  
P Staeger ◽  
F Ninane ◽  
L Mazzolai ◽  
D Moradpour ◽  
J Wasserfallen ◽  
...  
Keyword(s):  
Capillary Blood ◽  
Blood Sampling ◽  
Single Patient ◽  
Sampling Device ◽  
Capillary Blood Sampling
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