scholarly journals Changes in Plasma Tryptophan and Melatonin Content in Penned Sheep

1978 ◽  
Vol 31 (1) ◽  
pp. 49
Author(s):  
DJ Kennaway ◽  
KJ Porter ◽  
RF Seamark
Keyword(s):  
Circadian Rhythms ◽  
Plasma Levels ◽  
Blood Sampling ◽  
Night Time ◽  
Sampling Device ◽  
Blood Constituents ◽  
Circadian Changes ◽  
Plasma Tryptophan ◽  
Tryptophan Content ◽  
The Relationship

The present study was undertaken to examine the relationship between the plasma levels of melatonin and its precursor tryptophan. No circadian changes in plasma total tryptophan content were evident which could be related to the marked night-time rise in plasma melatonin. An automated programmable blood sampling device suited to studies of circadian rhythms in blood constituents is described.

scholarly journals Impacts of home lighting on human health

2021 ◽  
Vol 53 (5) ◽  
pp. 453-475
Author(s):  
C Ticleanu
Keyword(s):  
Energy Efficiency ◽  
Circadian Rhythms ◽  
Human Health ◽  
Electromagnetic Fields ◽  
Good Health ◽  
Sleep Patterns ◽  
Light At Night ◽  
Night Time ◽  
Potential Health ◽  
Areas Of Concern

Typical home lighting practice is mainly centred on visual aspects to enable safe movement between spaces, flexibility in multiuse spaces, a sense of aesthetics and energy efficiency. Whilst lighting impacts on the health of residents have not received similar consideration, this area is gaining increasing interest. This is even more important and actual in the context of the recent pandemic where people have been working or studying from home. A combination of bright daytime light and night-time darkness is essential for circadian entrainment and maintenance of a regular daily sleep–wake cycle, whereas exposure to light at night can negatively impact circadian rhythms and sleep patterns and ultimately lead to potential health problems. Additionally, lighting also has the potential to affect health through associated effects such as flicker, glare, optical hazards or electromagnetic fields. This article discusses the main areas of concern related to home lighting and outlines general recommendations to limit detrimental effects and contribute to good health.

scholarly journals Association of Urinary and Plasma Levels of Trimethylamine N-Oxide (TMAO) with Foods

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1426
Author(s):  
Mauro Lombardo ◽  
Giovanni Aulisa ◽  
Daniele Marcon ◽  
Gianluca Rizzo ◽  
Maria Grazia Tarsisano ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Fish Consumption ◽  
Plasma Levels ◽  
Cooking Methods ◽  
Saltwater Fish ◽  
Increased Risk ◽  
Mediator Role ◽  
Fish And Shellfish ◽  
The Relationship

Introduction: Trimethylamine N-oxide (TMAO) may play a key mediator role in the relationship between the diet, gut microbiota and cardiovascular diseases, particularly in people with kidney failure. The aim of this review is to evaluate which foods have a greater influence on blood or urinary trimethylamine N-oxide (TMAO) levels. Methods: 391 language articles were screened, and 27 were analysed and summarized for this review, using the keywords “TMAO” AND “egg” OR “meat” OR “fish” OR “dairy” OR “vegetables” OR “fruit” OR “food” in December 2020. Results: A strong correlation between TMAO and fish consumption, mainly saltwater fish and shellfish, but not freshwater fish, has been demonstrated. Associations of the consumption of eggs, dairy and meat with TMAO are less clear and may depend on other factors such as microbiota or cooking methods. Plant-based foods do not seem to influence TMAO but have been less investigated. Discussion: Consumption of saltwater fish, dark meat fish and shellfish seems to be associated with an increase in urine or plasma TMAO values. Further studies are needed to understand the relationship between increased risk of cardiovascular disease and plasma levels of TMAO due to fish consumption. Interventions coupled with long-term dietary patterns targeting the gut microbiota seem promising.

Affective labour and class distinction in the night-time economy

2021 ◽  
pp. 003802612110063
Author(s):  
Steven Threadgold ◽  
David Farrugia ◽  
Julia Coffey
Keyword(s):  
Symbolic Dynamics ◽  
Urban Areas ◽  
Service Work ◽  
Night Time ◽  
Feminist Analysis ◽  
Consumption Experience ◽  
Gendered Politics ◽  
The Aesthetic ◽  
The Relationship ◽  
Class Distinction

This article contributes to recent debates about the relationship between affective labour and class by exploring the classed distinctions enacted through affective labour in the urban night-time economy. Bringing theories of affective labour into a dialogue with Bourdieusian feminist analysis, the article explores the affective and symbolic dynamics of hospitality labour in a gentrified inner-urban neighbourhood of Melbourne, Australia. It shows how the practice of hospitality labour enacts classed distinctions and tensions emerging from the gentrification of inner-urban areas, and how the aesthetic and symbolic dimensions of class contribute to the valorisation of affect in hospitality venues. The valorisation of affect are processes in which the value attributed to an atmosphere or consumption experience is based on the forms of distinction practised within the venue, enacted in aesthetics, tastes and modes of embodiment. The article also shows how practices of class distinction – both ‘punching up’ and ‘managing down’ – are connected to the gendered politics of service work in the way that workers manage the threat of violence or sexual harassment in venues. In general, the article shows how the classed dynamics of gentrification are enacted in affective economies, and therefore how Bourdieusian analysis of class can be usefully deployed in theoretical debates about affective labour.

Endocannabinoid reactivity to acute stress: Investigation of the relationship between salivary and plasma levels

2021 ◽  
Vol 159 ◽  
pp. 108022
Author(s):  
Luke Ney ◽  
Caleb Stone ◽  
David Nichols ◽  
Kim Felmingham ◽  
Raimondo Bruno ◽  
...  
Keyword(s):  
Plasma Levels ◽  
Acute Stress ◽  
The Relationship

scholarly journals Plasma and cerebrospinal fluid inflammation and the blood-brain barrier in older surgical patients: the Role of Inflammation after Surgery for Elders (RISE) study

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Sarinnapha M. Vasunilashorn ◽  
◽  
Long H. Ngo ◽  
Simon T. Dillon ◽  
Tamara G. Fong ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Blood Brain Barrier ◽  
Plasma Levels ◽  
Inflammatory Markers ◽  
Brain Barrier ◽  
Markers Of Inflammation ◽  
Blood Brain ◽  
Csf Levels ◽  
The Relationship

Abstract Background Our understanding of the relationship between plasma and cerebrospinal fluid (CSF) remains limited, which poses an obstacle to the identification of blood-based markers of neuroinflammatory disorders. To better understand the relationship between peripheral and central nervous system (CNS) markers of inflammation before and after surgery, we aimed to examine whether surgery compromises the blood-brain barrier (BBB), evaluate postoperative changes in inflammatory markers, and assess the correlations between plasma and CSF levels of inflammation. Methods We examined the Role of Inflammation after Surgery for Elders (RISE) study of adults aged ≥ 65 who underwent elective hip or knee surgery under spinal anesthesia who had plasma and CSF samples collected at baseline and postoperative 1 month (PO1MO) (n = 29). Plasma and CSF levels of three inflammatory markers previously identified as increasing after surgery were measured using enzyme-linked immunosorbent assay: interleukin-6 (IL-6), C-reactive protein (CRP), and chitinase 3-like protein (also known as YKL-40). The integrity of the BBB was computed as the ratio of CSF/plasma albumin levels (Qalb). Mean Qalb and levels of inflammation were compared between baseline and PO1MO. Spearman correlation coefficients were used to determine the correlation between biofluids. Results Mean Qalb did not change between baseline and PO1MO. Mean plasma and CSF levels of CRP and plasma levels of YKL-40 and IL-6 were higher on PO1MO relative to baseline, with a disproportionally higher increase in CRP CSF levels relative to plasma levels (CRP tripled in CSF vs. increased 10% in plasma). Significant plasma-CSF correlations for CRP (baseline r = 0.70 and PO1MO r = 0.89, p < .01 for both) and IL-6 (PO1MO r = 0.48, p < .01) were observed, with higher correlations on PO1MO compared with baseline. Conclusions In this elective surgical sample of older adults, BBB integrity was similar between baseline and PO1MO, plasma-CSF correlations were observed for CRP and IL-6, plasma levels of all three markers (CRP, IL-6, and YKL-40) increased from PREOP to PO1MO, and CSF levels of only CRP increased between the two time points. Our identification of potential promising plasma markers of inflammation in the CNS may facilitate the early identification of patients at greatest risk for neuroinflammation and its associated adverse cognitive outcomes.

The Relationship of Certain Blood Constituents to Rate and Economy of Gain in Beef Cattle

1959 ◽  
Vol 18 (1) ◽  
pp. 314-322 ◽  
Author(s):  
R. L. Arthaud ◽  
A. B. Schultze ◽  
R. M. Koch ◽  
V. H. Arthaud
Keyword(s):  
Beef Cattle ◽  
Blood Constituents ◽  
Relationship Of ◽  
The Relationship

scholarly journals Anosognosia in People with Cognitive Impairment: Association with Cognitive Deficits and Behavioral Disturbances

2015 ◽  
Vol 5 (1) ◽  
pp. 42-50 ◽  
Author(s):  
Antonella De Carolis ◽  
Virginia Cipollini ◽  
Valentina Corigliano ◽  
Anna Comparelli ◽  
Micaela Sepe-Monti ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Deficits ◽  
Rating Scale ◽  
Motor Behavior ◽  
Psychiatric Symptoms ◽  
Early Stage ◽  
Functional Anatomy ◽  
Night Time ◽  
Behavioral Disturbances ◽  
The Relationship

Aims: To investigate, in a group of subjects at an early stage of cognitive impairment, the relationship between anosognosia and both cognitive and behavioral symptoms by exploring the various domains of insight. Methods: One hundred and eight subjects affected by cognitive impairment were consecutively enrolled. The level of awareness was evaluated by means of the Clinical Insight Rating Scale (CIRS). Psychiatric symptoms were evaluated using the Italian version of the Neuropsychiatric Inventory (NPI), whereas memory (memory index, MI) and executive (executive index, EI) functions were explored using a battery of neuropsychological tests and qualified by means of a single composite cognitive index score for each function. Results: A significant positive correlation between the total NPI score and global anosognosia score was found. Furthermore, both the MI and EI scores were lower in subjects with anosognosia than in those without anosognosia (p < 0.001 and p < 0.007, respectively). When the single domains of the CIRS were considered, anosognosia of reason of visit correlated with the EI score (r = -0.327, p = 0.01) and night-time behavioral disturbances (r = 0.225; p = 0.021); anosognosia of cognitive deficit correlated with depression (r = -0.193; p = 0.049) and the MI score (r = -0.201; p = 0.040); anosognosia of functional deficit correlated with the MI score (r = -0.257; p = 0.008), delusions (r = 0.232; p = 0.015) and aberrant motor behavior (r = 0.289; p = 0.003); anosognosia of disease progression correlated with the MI score (r = -0.236; p = 0.015), agitation (r = 0.247; p = 0.011), aberrant motor behavior (r = 0.351; p = 0.001) and night-time behavioral disturbances (r = 0.216; p = 0.027). Conclusions: Our study suggests that, in the early stage of cognitive impairment, anosognosia is associated with both cognitive deficits and behavioral disorders according to the specific functional anatomy of the symptoms.

The relationship between D 2 receptor occupancy and plasma levels on low dose oral haloperidol: a PET study

1997 ◽  
Vol 131 (2) ◽  
pp. 148-152 ◽  
Author(s):  
Shitij Kapur ◽  
Robert Zipursky ◽  
Paul Roy ◽  
Corey Jones ◽  
Gary Remington ◽  
...  
Keyword(s):  
Plasma Levels ◽  
Low Dose ◽  
Receptor Occupancy ◽  
Dose Oral ◽  
The Relationship

Design and modeling of microneedle integrated with microactuator for drug delivery

2014 ◽  
Vol 03 (03) ◽  
pp. 1450016
Author(s):  
K. Girija Sravani ◽  
Y. Srinivas ◽  
Bikash Swain ◽  
K. Sunil Banu ◽  
K. Srinivasa Rao
Keyword(s):  
Drug Delivery ◽  
Piezoelectric Actuator ◽  
Dimensional Stability ◽  
Blood Sampling ◽  
High Dimensional ◽  
Sampling Device ◽  
Metal Electrodes ◽  
New Model ◽  
Space Requirements ◽  
Manufacturing Time

Today's world has very much demand for the development of microscale devices, due to its less cost, space requirements, high-dimensional stability and especially manufacturing time. In this paper, we have design and simulated MEMS based microactuator and microneedle integration which will be very helpful for blood sampling device like e-mosquito. The dimensions of the modeled beam are of 100 mm long, 30 mm width, 10 mm thickness. This new design model consists of piezoceramic material sandwiched between two metal electrodes and the piezoelectric actuator is made with microneedle which will help for blood sampling purposes. The results after the simulation of this new model present that it will be suitable for blood sampling analysis with aluminum as electrodes and silicon as microneedle.

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