99 m Tc antigranulocyte monoclonal antibody imaging for the detection and assessment of inflammatory bowel disease newly diagnosed by colonoscopy in children

2001 ◽  
Vol 31 (11) ◽  
pp. 796-800 ◽  
Author(s):  
M. Charron ◽  
Carlo Di Lorenzo ◽  
Samuel A. Kocoshis ◽  
Mark P. Hickeson ◽  
Susan R. Orenstein ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Monoclonal Antibody ◽  
Bowel Disease ◽  
Newly Diagnosed ◽  
Antibody Imaging ◽  
Inflammatory Bowel ◽  
Monoclonal Antibody Imaging

Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of inflammatory bowel disease

2005 ◽  
Vol 101 (2) ◽  
pp. 210-216 ◽  
Author(s):  
Jienny Lee ◽  
Eun-Na Lee ◽  
Eun-Young Kim ◽  
Hae-Jung Park ◽  
Chi-Young Chang ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Monoclonal Antibody ◽  
Bowel Disease ◽  
Inflammatory Bowel

Assessing psychosocial functioning among youth with newly diagnosed inflammatory bowel disease (IBD): An interdisciplinary clinic approach.

2013 ◽  
Vol 1 (4) ◽  
pp. 333-343 ◽  
Author(s):  
Michele Herzer Maddux ◽  
Julie A. Bass ◽  
Christy Geraghty-Sirridge ◽  
Ellen Carpenter ◽  
Kathy Christenson
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Psychosocial Functioning ◽  
Newly Diagnosed ◽  
Inflammatory Bowel

Osteoporosis in newly diagnosed inflammatory bowel disease

2001 ◽  
Vol 121 (2) ◽  
pp. 504-505 ◽  
Author(s):  
Asghar Qasim ◽  
John Seery ◽  
C.A.O. Morain
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Newly Diagnosed ◽  
Inflammatory Bowel

Prevalence of undernutrition in newly diagnosed paediatric patients with inflammatory bowel disease

2021 ◽  
Vol 46 ◽  
pp. S757-S758
Author(s):  
D. Kofinova ◽  
R. Shentova ◽  
P. Hadzhiyski ◽  
H. Naydenov ◽  
P. Yaneva ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Newly Diagnosed ◽  
Paediatric Patients ◽  
Inflammatory Bowel

scholarly journals P803 Non-immunity against hepatitis B virus in patients with newly diagnosed inflammatory bowel disease

2018 ◽  
Vol 12 (supplement_1) ◽  
pp. S518-S518
Author(s):  
H S Lee ◽  
S J Yeo ◽  
E S Kim ◽  
B I Jang ◽  
Y J Lee ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Bowel Disease ◽  
Newly Diagnosed ◽  
B Virus ◽  
Inflammatory Bowel

scholarly journals Characterizing Clinical Features and Creating a Gene Expression Profile Associated With Pain Burden in Children With Inflammatory Bowel Disease

2019 ◽  
Vol 26 (8) ◽  
pp. 1283-1290 ◽  
Author(s):  
Victoria Grossi ◽  
Jeffrey S Hyams ◽  
Nicole C Glidden ◽  
Brittany E Knight ◽  
Erin E Young
Keyword(s):  
Gene Expression ◽  
Inflammatory Bowel Disease ◽  
Abdominal Pain ◽  
Bowel Disease ◽  
Newly Diagnosed ◽  
Pain Experience ◽  
Factors Affecting ◽  
Cq Method ◽  
Inflammatory Bowel ◽  
Rectal Biopsies

Abstract Background There is often dissociation between inflammatory activity and abdominal pain in children with inflammatory bowel disease (IBD), suggesting other factors may play a role in the pain experience. Methods Patients (8 to 17 years) newly diagnosed with IBD were enrolled in the ALLAY Study: Assessing Risk Factors for Abdominal Pain in Children with Inflammatory Bowel Disease (NCT02984059). At diagnostic colonoscopy, 3 rectal biopsies were collected, and gene expression analysis was performed using Qiagen RT2 Profiler Neuropathic and Inflammatory Pain PCR Array. Relative fold difference in gene expression for 84 pain-associated genes was calculated using the 2-ΔΔ Cq method compared with pain-free controls. Factors affecting pain burden (Pain Burden Interview; PBI) were analyzed, including age, sex, rectal inflammation, and gene expression. Data were analyzed using multiple stepwise linear regression and 2-tailed t tests (P ≤ 0.05). Results Thirty-nine newly diagnosed IBD patients were included (65% male, mean age 12.75 years [SD 2.63], 23 Crohn’s disease, 16 ulcerative colitis), along with 3 controls. Mean PBI score was 7.73 (SD 6.4, range 0 to 23) for all patients. Age and sex were not predictive of pain burden, but disease activity score was (P = 0.03). Expression of TRPV3, OPRM1, P2X3, SCN9A, PTGS2, and MAPK14 were associated with PBI score. Subsequent 2-tailed t tests comparing patients with no pain (PBI score ≦ 2, N = 11) to those with pain (PBI > 2, N = 28) confirmed differential expression of TRPV3, PTGS2, and MAPK14 was in patients with pain (all P < 0.05). Conclusion Pain burden in newly diagnosed IBD patients may be linked to TRPV3, PTGS2, and MAPK14 expression, suggesting potential therapeutic targets for managing pain in IBD.

632 - Immunoglobulin A-Coated Bacteria Represent a Unique Subset of the Microbiome in Patients with Newly Diagnosed Inflammatory Bowel Disease

2018 ◽  
Vol 154 (6) ◽  
pp. S-132-S-133
Author(s):  
Jason M. Shapiro ◽  
José C. Clemente ◽  
Noah Palm ◽  
Marcel de Zoete ◽  
Yaro Laenen ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Immunoglobulin A ◽  
Newly Diagnosed ◽  
Inflammatory Bowel
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