Assessing psychosocial functioning among youth with newly diagnosed inflammatory bowel disease (IBD): An interdisciplinary clinic approach.

2013 ◽  
Vol 1 (4) ◽  
pp. 333-343 ◽  
Author(s):  
Michele Herzer Maddux ◽  
Julie A. Bass ◽  
Christy Geraghty-Sirridge ◽  
Ellen Carpenter ◽  
Kathy Christenson
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Psychosocial Functioning ◽  
Newly Diagnosed ◽  
Inflammatory Bowel

Osteoporosis in newly diagnosed inflammatory bowel disease

2001 ◽  
Vol 121 (2) ◽  
pp. 504-505 ◽  
Author(s):  
Asghar Qasim ◽  
John Seery ◽  
C.A.O. Morain
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Newly Diagnosed ◽  
Inflammatory Bowel

Prevalence of undernutrition in newly diagnosed paediatric patients with inflammatory bowel disease

2021 ◽  
Vol 46 ◽  
pp. S757-S758
Author(s):  
D. Kofinova ◽  
R. Shentova ◽  
P. Hadzhiyski ◽  
H. Naydenov ◽  
P. Yaneva ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Newly Diagnosed ◽  
Paediatric Patients ◽  
Inflammatory Bowel

scholarly journals P803 Non-immunity against hepatitis B virus in patients with newly diagnosed inflammatory bowel disease

2018 ◽  
Vol 12 (supplement_1) ◽  
pp. S518-S518
Author(s):  
H S Lee ◽  
S J Yeo ◽  
E S Kim ◽  
B I Jang ◽  
Y J Lee ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Bowel Disease ◽  
Newly Diagnosed ◽  
B Virus ◽  
Inflammatory Bowel

scholarly journals Characterizing Clinical Features and Creating a Gene Expression Profile Associated With Pain Burden in Children With Inflammatory Bowel Disease

2019 ◽  
Vol 26 (8) ◽  
pp. 1283-1290 ◽  
Author(s):  
Victoria Grossi ◽  
Jeffrey S Hyams ◽  
Nicole C Glidden ◽  
Brittany E Knight ◽  
Erin E Young
Keyword(s):  
Gene Expression ◽  
Inflammatory Bowel Disease ◽  
Abdominal Pain ◽  
Bowel Disease ◽  
Newly Diagnosed ◽  
Pain Experience ◽  
Factors Affecting ◽  
Cq Method ◽  
Inflammatory Bowel ◽  
Rectal Biopsies

Abstract Background There is often dissociation between inflammatory activity and abdominal pain in children with inflammatory bowel disease (IBD), suggesting other factors may play a role in the pain experience. Methods Patients (8 to 17 years) newly diagnosed with IBD were enrolled in the ALLAY Study: Assessing Risk Factors for Abdominal Pain in Children with Inflammatory Bowel Disease (NCT02984059). At diagnostic colonoscopy, 3 rectal biopsies were collected, and gene expression analysis was performed using Qiagen RT2 Profiler Neuropathic and Inflammatory Pain PCR Array. Relative fold difference in gene expression for 84 pain-associated genes was calculated using the 2-ΔΔ Cq method compared with pain-free controls. Factors affecting pain burden (Pain Burden Interview; PBI) were analyzed, including age, sex, rectal inflammation, and gene expression. Data were analyzed using multiple stepwise linear regression and 2-tailed t tests (P ≤ 0.05). Results Thirty-nine newly diagnosed IBD patients were included (65% male, mean age 12.75 years [SD 2.63], 23 Crohn’s disease, 16 ulcerative colitis), along with 3 controls. Mean PBI score was 7.73 (SD 6.4, range 0 to 23) for all patients. Age and sex were not predictive of pain burden, but disease activity score was (P = 0.03). Expression of TRPV3, OPRM1, P2X3, SCN9A, PTGS2, and MAPK14 were associated with PBI score. Subsequent 2-tailed t tests comparing patients with no pain (PBI score ≦ 2, N = 11) to those with pain (PBI > 2, N = 28) confirmed differential expression of TRPV3, PTGS2, and MAPK14 was in patients with pain (all P < 0.05). Conclusion Pain burden in newly diagnosed IBD patients may be linked to TRPV3, PTGS2, and MAPK14 expression, suggesting potential therapeutic targets for managing pain in IBD.

632 - Immunoglobulin A-Coated Bacteria Represent a Unique Subset of the Microbiome in Patients with Newly Diagnosed Inflammatory Bowel Disease

2018 ◽  
Vol 154 (6) ◽  
pp. S-132-S-133
Author(s):  
Jason M. Shapiro ◽  
José C. Clemente ◽  
Noah Palm ◽  
Marcel de Zoete ◽  
Yaro Laenen ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Immunoglobulin A ◽  
Newly Diagnosed ◽  
Inflammatory Bowel

scholarly journals P-139 Potential Barriers to Inflammatory Bowel Disease Education Visits for Newly Diagnosed Pediatric Patients

2014 ◽  
Vol 20 ◽  
pp. S84
Author(s):  
Higuchi Leslie ◽  
Peleggi Analise ◽  
Russell George ◽  
Kerr Jessica ◽  
Arbaugh Carlie ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Pediatric Patients ◽  
Newly Diagnosed ◽  
Potential Barriers ◽  
Inflammatory Bowel

scholarly journals A60 THE INCIDENCE OF INFLAMMATORY BOWEL DISEASE IS DECREASING IN SASKATCHEWAN: A POPULATION-BASED COHORT STUDY

2020 ◽  
Vol 3 (Supplement_1) ◽  
pp. 71-73
Author(s):  
J A Osei ◽  
J Peña-Sánchez ◽  
S Fowler ◽  
N Muhajarine ◽  
G G Kaplan ◽  
...  
Keyword(s):  
Health Care ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Population Based ◽  
Incidence Rates ◽  
Age Group ◽  
Newly Diagnosed ◽  
Average Annual Incidence ◽  
Inflammatory Bowel ◽  
Group Sex

Abstract Background Canada has one of the highest inflammatory bowel disease (IBD) incidence rates worldwide, although within Canada rates vary. Evidence show increasing incidence rates of IBD in Ontario (i.e. adults aged 30–60), stable in Alberta and decreasing in Manitoba. Additionally, higher incident rates of IBD have been identified among urban regions compared to rural regions. There is limited data on the incidence of IBD in Saskatchewan. Aims The study objectives were to 1) estimate IBD incidence rates in Saskatchewan from 1999 to 2016, and 2) test for differences in IBD incidence rates for rural and urban regions of Saskatchewan. Methods A population-based study was conducted using linked provincial administrative health databases. Individuals age 18+ old with newly diagnosed Crohn’s disease (CD) or ulcerative colitis (UC) were identified using a validated case definition. Generalized linear models with a negative binomial distribution were used to estimate incidence rates and incidence rate ratios (IRR) adjusted for age group, sex, and rurality with 95% confidence intervals (95%CI). Results In total, 4,908 newly diagnosed individuals with IBD were included. The average annual incidence rate of IBD decreased from 75 (95%CI 67–84) per 100,000 people in 1999 to 15 (95%CI 12–18) per 100,000 population in 2016. This decrease was evident in both UC (from 36/100,000 [95%CI 31–42] in 1999 to 6/100,000 [95%CI 4–8] in 2016) and CD (37/100,000 [95%CI 32–42] in 1999 to 8/100,000 [95%CI 6–10] in 2016). A significant decline of 6.9% (95%CI 6.2–7.6) in the average annual incidence of IBD was estimated between 1999 and 2016 (see Figure 1). Urban residents had a greater overall risk of IBD (IRR=1.19, 95%CI 1.11–1.27) than rural residents. This risk difference was statistically significant for CD (IRR=1.25, 95%CI 1.14–1.36), but not UC (IRR=1.08, 95%CI 0.97–1.19). Conclusions A decreasing trend in IBD incidence in Saskatchewan was identified after adjusting for age group, sex, and rural/urban region of residence. Around 150 new cases of IBD are still diagnosed annually in Saskatchewan, but this estimate is lower than estimates from other provinces. Urban dwellers have a 25% higher risk of CD onset compared to their rural counterparts. This finding could suggest the presence of specific risk factors in urban settings that require further investigation. Health care providers and decision-makers should plan IBD-specific health care programs taking into account these specific IBD rates in Saskatchewan. Funding Agencies College of Medicine, University of Saskatchewan

Sa1159 Infection-Related HospitalIzations in Patients Newly Diagnosed With Inflammatory Bowel Disease: Results From a Population-Based Registry

2015 ◽  
Vol 148 (4) ◽  
pp. S-243-S-244
Author(s):  
Wai K. Leung ◽  
Lung-Yi Mak ◽  
Wai Pan To ◽  
Kwan-Lung Michael Ko ◽  
Hai Yun Shi ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Population Based ◽  
Newly Diagnosed ◽  
Inflammatory Bowel ◽  
Population Based Registry
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