Characterization of a major cell wall antigen and potential adhesin in three strains of Candida albicans

1994 ◽  
Vol 162 (1-2) ◽  
pp. 33-40
Author(s):  
W. Jenq ◽  
Chi Lan Chen ◽  
Chun Chang ◽  
Richard F. E. Crang
Keyword(s):  
2015 ◽  
Vol 62 (4) ◽  
pp. 825-835 ◽  
Author(s):  
Karolina Seweryn ◽  
Justyna Karkowska-Kuleta ◽  
Natalia Wolak ◽  
Oliwia Bochenska ◽  
Sylwia Kedracka-Krok ◽  
...  

2013 ◽  
Vol 457 (2) ◽  
pp. 347-360 ◽  
Author(s):  
Emeline Fabre ◽  
Ghenima Sfihi-Loualia ◽  
Marilyne Pourcelot ◽  
Bernadette Coddeville ◽  
Frédéric Krzewinski ◽  
...  

Candida albicans is a yeast responsible for serious infections in immunocompromised patients. In the present paper, we report the identification of an enzyme that initiates the synthesis of a bioactive cell wall carbohydrate antigenic factor, the β-mannans.


1993 ◽  
Vol 61 (11) ◽  
pp. 4842-4847 ◽  
Author(s):  
J Ponton ◽  
A Marot-Leblond ◽  
P A Ezkurra ◽  
B Barturen ◽  
R Robert ◽  
...  

2004 ◽  
Vol 3 (3) ◽  
pp. 776-784 ◽  
Author(s):  
Henrike Lotz ◽  
Kai Sohn ◽  
Herwig Brunner ◽  
Fritz A. Mühlschlegel ◽  
Steffen Rupp

ABSTRACT The transcription factor Rim101p of Candida albicans has been shown to play a major role in pH-dependent gene regulation. Rim101p is involved in cell wall biosynthesis, since it regulates PHR1 and PHR2, two almost functionally redundant cell wall glycosidases important for adaptation to either neutral or acidic habitats within the human host. To identify additional cell wall components regulated by Rim101p, we performed transcriptional profiling with a cell wall-specific DNA microarray. We showed that Rim101p contributes to the activation of known hypha-specific genes such as HWP1 and RBT1 but is also required for repression of the previously uncharacterized potential cell wall genes RBR1, RBR2, and RBR3. Further characterization of RBR1 revealed that it encodes a small glycosylphosphatidyl inositol protein that is expressed under acidic conditions predominantly at low temperature. Deletion of the gene resulted in a filamentation defect at low pH. Most interestingly, NRG1, a transcriptional repressor of hyphal growth in C. albicans, was required for RBR1 expression. The apparently activating effect of NRG1 observed in this study has not been described before. In addition, we showed that expression of NRG1 is not only temperature but also pH dependent.


2010 ◽  
Vol 165 (3) ◽  
pp. 250-258 ◽  
Author(s):  
Peter Hayek ◽  
Leila Dib ◽  
Pascal Yazbeck ◽  
Berna Beyrouthy ◽  
Roy A. Khalaf

1994 ◽  
Vol 162 (1-2) ◽  
pp. 33-40 ◽  
Author(s):  
Wheamei Jenq ◽  
Chi Lan Chen ◽  
Chun Chang Chang ◽  
Richard F. E. Crang
Keyword(s):  

1991 ◽  
Vol 59 (7) ◽  
pp. 2324-2332 ◽  
Author(s):  
J L Lopez-Ribot ◽  
M Casanova ◽  
J P Martinez ◽  
R Sentandreu

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