scholarly journals Maternal low protein diet in rats programmes fatty acid desaturase activities in the offspring

Diabetologia ◽  
1998 ◽  
Vol 41 (11) ◽  
pp. 1337-1342 ◽  
Author(s):  
S. E. Ozanne ◽  
N. D. Martensz ◽  
C. J. Petry ◽  
C. L Loizou ◽  
C. N. Hales
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Desaturase ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Low Protein

FP384EFFECT OF OMEGA-3 FATTY ACID AND MENAQUINONE-7 ON OSTEOPENIA AND SARCOPENIA IN ADENINE AND LOW PROTEIN DIET INDUCED UREMIC RATS

2018 ◽  
Vol 33 (suppl_1) ◽  
pp. i162-i163
Author(s):  
SuMi Lee ◽  
Eu Gene Jeong ◽  
Sung Hyun Son ◽  
Hyuck Jae Choi ◽  
Young Ki Son ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Omega 3 ◽  
Omega 3 Fatty Acid ◽  
Low Protein

scholarly journals Low-Protein Diet Supplemented with Medium-Chain Fatty Acid Glycerides Improves the Growth Performance and Intestinal Function in Post-Weaning Piglets

Animals ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 1852
Author(s):  
Zhijuan Cui ◽  
Xianze Wang ◽  
Zhenping Hou ◽  
Simeng Liao ◽  
Ming Qi ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Growth Performance ◽  
Chain Fatty Acid ◽  
Medium Chain Fatty Acid ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Weaned Piglets ◽  
Medium Chain ◽  
Low Protein ◽  
Glycerol Monolaurate

Medium-chain fatty acid glycerides have been shown to provide energy for rapid oxidation in the body. The study was conducted to investigate the effects of dietary supplementation with medium-chain fatty acid glyceride on the growth performance and intestinal health of weaned piglets fed with a low-protein diet. Nighty healthy weaned piglets were randomly divided into five treatments: NP (Normal protein treatment, normal-protein diet no antibiotics included); NC (Negative control, low-protein diet no antibiotics included); PC (Positive control, low-protein diet +75 mg/kg quinocetone, 20 mg/kg virginiamycin and 50 mg/kg aureomycin); MCT (tricaprylin + tricaprin treatment, low-protein diet + tricaprylin + tricaprin); GML (glycerol monolaurate treatment, low-protein diet + glycerol monolaurate). The results showed that the average daily feed intake (ADFI) of the MCT treatment was significantly higher than that of the NP, NC treatments (p < 0.05). In the jejunum, the villus height of the GML treatment was significantly lower than that of the PC treatment (p < 0.05), and the number of goblet cells in the GML treatment was higher than that in the NC treatment (p < 0.05). Compared with the NC treatment, the MCT treatment significantly increased the level of claudin-1, Zonula occludens-1(ZO-1), while the GML treatment significantly increased the level of claudin-1, occludin, ZO-1 (p < 0.05). In the ileum, the level of ZO-1 in the GML treatment was significantly higher than that in the NP, NC, PC treatments (p < 0.05). Compared with the NC treatment, the GML treatment significantly increased the level of Secretory immunoglobulin A (SIgA) in the ileum and serum, while the MCT treatment significantly increased the level of SIgA and decreased the level of interleukin-6 (IL-6) in the ileum (p < 0.05). These results showed that the addition of medium-chain fatty acid glycerides to a low-protein diet could improve the growth performance and intestinal functional barrier of weaned piglets and also improve the immune function of weaned piglets.

scholarly journals Low protein diet and methyl-donor supplements modify testicular physiology in mice

Reproduction ◽  
2020 ◽  
Vol 159 (5) ◽  
pp. 627-641 ◽  
Author(s):  
Hannah L Morgan ◽  
Isaac Ampong ◽  
Nader Eid ◽  
Charlène Rouillon ◽  
Helen R Griffiths ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Choline Chloride ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Fatty Acid Profiles ◽  
Serum Fatty Acid ◽  
Methyl Donors ◽  
Low Protein ◽  
The Impact

The link between male diet and sperm quality has received significant investigation. However, the impact diet and dietary supplements have on the testicular environment has been examined to a lesser extent. Here, we establish the impact of a sub-optimal low protein diet (LPD) on testicular morphology, apoptosis and serum fatty acid profiles. Furthermore, we define whether supplementing a LPD with specific methyl donors abrogates any detrimental effects of the LPD. Male C57BL6 mice were fed either a control normal protein diet (NPD; 18% protein; n = 8), an isocaloric LPD (LPD; 9% protein; n = 8) or an LPD supplemented with methyl donors (MD-LPD; choline chloride, betaine, methionine, folic acid, vitamin B12; n = 8) for a minimum of 7 weeks. Analysis of male serum fatty acid profiles by gas chromatography revealed elevated levels of saturated fatty acids and lower levels of mono- and polyunsaturated fatty acids in MD-LPD males when compared to NPD and/or LPD males. Testes of LPD males displayed larger seminiferous tubule cross section area when compared to NPD and MD-LPD males, while MD-LPD tubules displayed a larger luminal area. Furthermore, TUNNEL staining revealed LPD males possessed a reduced number of tubules positive for apoptosis, while gene expression analysis showed MD-LPD testes displayed decreased expression of the pro-apoptotic genes Bax, Csap1 and Fas when compared to NPD males. Finally, testes from MD-LPD males displayed a reduced telomere length but increased telomerase activity. These data reveal the significance of sub-optimal nutrition for paternal metabolic and reproductive physiology.

scholarly journals A maternal low protein diet programs glucose and fatty acid metabolism differentially in adult male and female mouse offspring

2011 ◽  
Vol 25 (S1) ◽  
Author(s):  
Torsten Plosch ◽  
Esther M.E. Straten ◽  
Theo H. Dijk ◽  
Vincent W. Bloks ◽  
Henkjan J. Verkade ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Metabolism ◽  
Adult Male ◽  
Female Mouse ◽  
Acid Metabolism ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Male And Female ◽  
Low Protein
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