Trace element maps and the regional distribution of human diseases

Author(s):  
Iain Thornton
Metallomics ◽  
2017 ◽  
Vol 9 (10) ◽  
pp. 1376-1388 ◽  
Author(s):  
Ashima Bhattacharjee ◽  
Kaustav Chakraborty ◽  
Aditya Shukla

Copper is a trace element essential for almost all living organisms, however the level of intracellular copper needs to be tightly regulated. This review explores the existing literature on the role of glutathione in regulating cellular copper homeostasis.


2009 ◽  
Vol 59 ◽  
pp. 94-103
Author(s):  
ANANDA S. PRASAD ◽  
John R. Detroit
Keyword(s):  

1975 ◽  
Vol 19 ◽  
pp. 521-532 ◽  
Author(s):  
R. D. Lear ◽  
H. A. Van Rinsvelt ◽  
W. R. Adams

The proton beam from the 4 MV Van de Graaff at the University of Florida has been used in conjunction with a 5 mm thick lithium drifted silicon, Si (Li), x-ray detector to do elemental analysis of biomedical samples by proton-induced x-ray emission (PIXE). Several hundred samples, mostly autopsy organs ashed at high, temperature, have been analyzed by this method. The main object of the research is the correlation between human diseases and trace element levels. The target mass has been determined by monitoring the elastically scattered protons from the sample. This technique considerably reduces the target preparation time by eliminating careful weighings or doping of each individual sample.


1994 ◽  
Vol 25 (5) ◽  
pp. 345-358 ◽  
Author(s):  
Abdulghaffar S. A. Bazuhair ◽  
Zekâi Şen

Trace elements are rarely distributed in earth's crust and they are invariably in low concentrations. Due to this low concentration they are not analyzed by conventional hydrochemical methods but by rather special techniques with great care. The trace elements are especially useful in detecting the origin of the groundwater in an area. Their regional distribution helps to obtain significant clues on the groundwater movement and mixture processes. It is proposed, herein to assess the trace element concentration available at far distant points by employing the cumulative semivariogram models. These models furnish further systematic interpretations about trace element areal extends, concentration directions, groundwater movement and its continuity.


Author(s):  
Matthew S. Huber ◽  
Frederick Roelofse ◽  
Christian Koeberl ◽  
Marian Tredoux

ABSTRACT The Bon Accord nickel body has been known since the 1920s to contain rocks with up to 50 wt% NiO. Numerous nickel-rich minerals have been described from this deposit. However, none of these minerals contains significant Cu or S, making the deposit chemically distinct from all other known Ni deposits. The origin of the Bon Accord nickel body is highly contentious, with previous studies suggesting three major possible origins: (1) a hydrothermal origin; (2) an Fe-Ni meteorite that fell into and was altered by an active ultramafic lava flow; or (3) a deep mantle plume that contained a fragment of nickel-rich material. Here, we present new field, petrograph ic, and geochemical data in an attempt to constrain the origin of this enigmatic body. Based on our fieldwork, there are at least two distinct Ni-rich bodies. Based on the trace-element chemistry, the protolith of the body was a komatiite, likely belonging to the Weltevreden Formation. Because the Ni end member of olivine (liebenbergite) is present in the form of euhedral crystals, this mineral most likely crystallized from a Ni-rich melt. The redistribution of the nickel appears to be due to hydrothermal activity that occurred during the intrusion of the Stentor pluton. Consistent with previous studies, we find that the komatiitic affinity of the host rocks, the stratigraphic controls on the deposit, and the regional distribution of Ni-rich material are inconsistent with a meteorite origin; instead, a komatiite plume sampling a Ni-rich portion of the mantle is currently the best explanation for the origin of the Ni-rich material.


Author(s):  
A. Kawaoi

Numbers of immunological approach have been made to the amyloidosis through the variety of predisposing human diseases and the experimentally induced animals by the greater number of agents. The results suggest an important role of impaired immunity involving both humoral and cell-mediated aspects.Recently the author has succeeded in producing amyloidosis in the rabbits and mice by the injections of immune complex of heat denatured DNA.The aim of this report is to demonstrate the details of the ultrastructure of the amyloidosis induced by heterologous insoluble immune complex. Eleven of twelve mice, dd strain, subcutaneously injected twice a week with Freund's complete adjuvant and four of seven animals intraperitonially injected developed systemic amyloidosis two months later from the initial injections. The spleens were electron microscopically observed.


1986 ◽  
Vol 390 (2) ◽  
pp. 302-308 ◽  
Author(s):  
J BACHEVALIER ◽  
L UNGERLEIDER ◽  
J BLANCHEONEILL ◽  
D FRIEDMAN

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