glutathione homeostasis
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Phyton ◽  
2021 ◽  
Vol 90 (2) ◽  
pp. 373-388
Author(s):  
Hesham F. Alharby ◽  
Mirza Hasanuzzaman ◽  
Hassan S. Al-Zahrani ◽  
Khalid Rehman Hakeem

Redox Biology ◽  
2020 ◽  
pp. 101827
Author(s):  
Rachael Bok ◽  
Damian D. Guerra ◽  
Ramón A. Lorca ◽  
Sara A. Wennersten ◽  
Peter S. Harris ◽  
...  

2020 ◽  
Vol 25 (6) ◽  
pp. 919-928 ◽  
Author(s):  
Ines Amara ◽  
Amal Salah ◽  
Rim Timoumi ◽  
Emna Annabi ◽  
Maria Scuto ◽  
...  

2020 ◽  
Vol 21 (4) ◽  
pp. 1393 ◽  
Author(s):  
Sylwia Wrotek ◽  
Justyna Sobocińska ◽  
Henryk M. Kozłowski ◽  
Małgorzata Pawlikowska ◽  
Tomasz Jędrzejewski ◽  
...  

Glutathione is one of the most important and potent antioxidants. The development of pharmacological compounds that can either increase or decrease glutathione concentrations has allowed investigation into the role of glutathione in various biological processes, including immune responses. Recent findings have shown that glutathione not only affects certain factors involved in immunological processes but also modifies complex immune reactions such as fever. Until recently, it was not known why some patients do not develop fever during infection. Data suggest that fever induction is associated with oxidative stress; therefore, antioxidants such as glutathione can reduce pyrexia. Surprisingly, new studies have shown that low glutathione levels can also inhibit fever. In this review, we focus on recent advances in this area, with an emphasis on the role of glutathione in immune responses accompanied by fever. We describe evidence showing that disturbed glutathione homeostasis may be responsible for the lack of fever during infections. We also discuss the biological significance of the antipyretic effects produced by pharmacological glutathione modulators.


2020 ◽  
Vol 11 (9) ◽  
pp. 7681-7695
Author(s):  
Zhihong Zhang ◽  
Songtao Fan ◽  
Danfei Huang ◽  
Tao Xiong ◽  
Shaoping Nie ◽  
...  

FAOP showed superior performance by promoting GSH biosynthesis, normalizing the expression level of bile acid receptors and related enzymes, and upregulating hepatic SCFA receptors and fecal SCFA production.


2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Lixue Cao ◽  
Geyan Wu ◽  
Jinrong Zhu ◽  
Zhanyao Tan ◽  
Dongni Shi ◽  
...  

2019 ◽  
Vol 10 ◽  
Author(s):  
Yakun Chen ◽  
Qingbo Zheng ◽  
Xiaolin Jia ◽  
Keqin Chen ◽  
Yi Wang ◽  
...  

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