Demonstration of thyrotropin binding sites in orbital connective tissue: Possible role in the pathogenesis of thyroid-associated ophthalmopathy

1994 ◽  
Vol 17 (3) ◽  
pp. 163-170 ◽  
Author(s):  
P. Perros ◽  
P. Kendall-Taylor
Keyword(s):  
Connective Tissue ◽  
Binding Sites ◽  
Thyroid Associated Ophthalmopathy ◽  
Orbital Connective Tissue

Differentially expressed circular RNAs in orbital adipose/connective tissue from patients with thyroid-associated ophthalmopathy

2020 ◽  
Vol 196 ◽  
pp. 108036 ◽  
Author(s):  
Lianqun Wu ◽  
Rongmei Zhou ◽  
Jiale Diao ◽  
Xinxin Chen ◽  
Jiancheng Huang ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Differentially Expressed ◽  
Circular Rnas ◽  
Thyroid Associated Ophthalmopathy

scholarly journals Changes of orbital connective tissue after bimatoprost injection. Experimental study in rats

2016 ◽  
Vol 75 ◽  
Author(s):  
Nilson Lopes da Fonseca Junior ◽  
Giuliana Petri ◽  
Juliana Mora Veridiano ◽  
José Ricardo Carvalho Lima Rehder
Keyword(s):  
Experimental Study ◽  
Connective Tissue ◽  
Orbital Connective Tissue

scholarly journals Viscoelastic properties of bovine orbital connective tissue and fat: constitutive models

2011 ◽  
Vol 10 (6) ◽  
pp. 901-914 ◽  
Author(s):  
Lawrence Yoo ◽  
Vijay Gupta ◽  
Choongyeop Lee ◽  
Pirouz Kavehpore ◽  
Joseph L. Demer
Keyword(s):  
Connective Tissue ◽  
Viscoelastic Properties ◽  
Constitutive Models ◽  
Orbital Connective Tissue

scholarly journals Density and distribution of α-bungarotoxin-binding sites in postsynaptic structures of regenerated rat skeletal muscle

1981 ◽  
Vol 88 (2) ◽  
pp. 338-345 ◽  
Author(s):  
D Bader
Keyword(s):  
Skeletal Muscle ◽  
Connective Tissue ◽  
Morphometric Analysis ◽  
Binding Sites ◽  
Acetylcholine Receptors ◽  
Mammalian Skeletal Muscle ◽  
Rat Skeletal Muscle ◽  
Em Autoradiography ◽  
Postsynaptic Differentiation ◽  
Vertebrate Skeletal Muscle

Acetylcholine receptors (AChR) are organized in a discrete and predictable fashion in the postsynaptic regions of vertebrate skeletal muscle. When muscle is damaged, nerves and myofibers including muscular elements of the endplate degenerate, but the connective tissue elements survive. Muscle fibers regenerate within the basal lamina of the original myofiber. Postsynaptic differentiation in regenerated mammalian skeletal muscle can occur in different ways: (a) at the site of the original endplate in the presence or absence of the nerve, or (b) at ectopic regions of the regenerated myofiber in the presence of the nerve when the original endplate is not present. The present study used (125)I-α- bungarotoxin ((125)I-α-BuTX) and EM autoradiography to examine the density and distribution of AChR in postsynaptic structures regenerated at the site of the original endplate in the absence of the nerve and at ectopic sites of the myofiber in the presence of the nerve when the original endplate was removed. In regenerated myofibers, the density of α-BuTX-binding sites fell within the range of densities observed in uninjured muscle whether postsynaptic differentiation occurred at the site of the original endplate in the absence of the nerve or at an originally ectopic position of the regenerated myofiber. In addition, the distribution of α-BuTX-binding sites within the regenerated postsynaptic regions closely resembled the distribution of apha-BuTX- binding sites in uninjured muscle. Morphometric analysis was performed on postsynaptic structures formed at the site of the original endplate in the absence of the nerve or at an ectopic position of the regenerated myofiber by interaction of the nerve and muscle. Although variation in the depth of the primary cleft occurred, there was little difference between the overall structure of regenerated postsynaptic structures and that of endplates of uninjured muscles.

Autoantibodies to Igf-1 Binding Sites in Thyroid Associated Ophthalmopathy

Autoimmunity ◽  
1993 ◽  
Vol 16 (4) ◽  
pp. 251-257 ◽  
Author(s):  
David R. Weightman ◽  
Petros Perros ◽  
Ibrahim H. Sherif ◽  
Pat Kendall-Taylor
Keyword(s):  
Binding Sites ◽  
Thyroid Associated Ophthalmopathy

scholarly journals Distribution of soltriol [1,25(OH)2-vitamin D3] binding sites in male sex organs of the mouse: an autoradiographic study.

1989 ◽  
Vol 37 (7) ◽  
pp. 1083-1086 ◽  
Author(s):  
G Schleicher ◽  
T H Privette ◽  
W E Stumpf
Keyword(s):  
Connective Tissue ◽  
Lamina Propria ◽  
Vitamin D3 ◽  
Sertoli Cells ◽  
Binding Sites ◽  
Autoradiographic Study ◽  
Ventral Prostate ◽  
Male Sex ◽  
Labeling Pattern ◽  
Caput Epididymidis

After injection of [3H]-1,25(OH)2-vitamin D3 (soltriol), nuclear labeling is found in Sertoli cells of testes, being highest at the stage of spermiosis, in epithelium of efferent ductules and caput epididymidis and in connective tissue cells of epididymis, in lamina propria and muscular sheath of deferent duct, and in epithelium and muscular sheath of dorsal and ventral prostate of the mouse. This labeling pattern is characteristic for [3H]-soltriol and differs from that for [3H]-dihydrotestosterone and [3H]-estradiol, although with overlap. The nuclear labeling with [3H]-soltriol suggests an action of the hormone on certain processes during spermatogenesis, on sperm maturation, on epididymal fluid resorption, and on secretion and transport of spermatozoa.

Sign in / Sign up

Export Citation Format

Share Document