Vascular risk factors, alcohol intake, and cognitive decline

2008 ◽  
Vol 12 (6) ◽  
pp. 376-381 ◽  
Author(s):  
F. Panza ◽  
C. Capurso ◽  
A. D’Introno ◽  
A. M. Colacicco ◽  
V. Frisardi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cognitive Decline ◽  
Alcohol Intake ◽  
Vascular Risk Factors ◽  
Vascular Risk

The Spectrum of Cerebrovascular Disease and Associated Cognitive Decline

2019 ◽  
pp. 574-599
Author(s):  
Victoria J. Williams ◽  
Steven E. Arnold ◽  
David H. Salat
Keyword(s):  
Risk Factors ◽  
Cognitive Impairment ◽  
Cerebrovascular Disease ◽  
Cognitive Decline ◽  
Vascular Dementia ◽  
Structure And Function ◽  
Vascular Risk Factors ◽  
Vascular Health ◽  
Vascular Risk ◽  
And Function

Throughout the lifespan, common variations in systemic health and illness contribute to alterations in vasculature structure and function throughout the body, significantly increasing risk for cardiovascular and cerebrovascular disease (CVD). CVD is a prevalent cause of mortality in late life; it also promotes brain alterations, contributing to cognitive decline and, when severe, vascular dementia. Even prior to diseased states, individual variation in CVD risk is associated with structural and functional brain alterations. Yet, how cumulative asymptomatic alterations in vessel structure and function contribute to more subtle changes in brain tissue integrity and function that emerge in late life is unclear. Finally, vascular risk factors are associated with the clinical progression of neurodegenerative diseases such as Alzheimer’s disease (AD); however, recent theory posits that vascular degeneration may serve a contributory role in these conditions. This chapter reviews how lifespan changes in vascular health contribute to degenerative changes in neural tissue and the subsequent development of cognitive impairment and/or vascular dementia. It first discusses associations between vascular risk factors and cognition and also how declining vascular health may lead to cognitive impairment and dementia. Next, it identifies basic aspects of cerebrovascular anatomy and physiology sustaining tissue health and discusses how vulnerabilities of this system contribute to neurodegenerative changes. Finally, it reviews evidence of vascular contributions to AD and presents ideas for future research to better understand the full spectrum of cerebrovascular contributions to brain aging, cognitive decline, and dementia.

Cognitive decline precedes late-life longitudinal changes in vascular risk factors

2010 ◽  
Vol 81 (9) ◽  
pp. 1028-1032 ◽  
Author(s):  
P. van Vliet ◽  
R. G. J. Westendorp ◽  
D. van Heemst ◽  
A. J. M. de Craen ◽  
A. M. Oleksik
Keyword(s):  
Risk Factors ◽  
Cognitive Decline ◽  
Late Life ◽  
Vascular Risk Factors ◽  
Vascular Risk ◽  
Longitudinal Changes

The influence of vascular risk factors on cognitive decline in patients with dementia: A systematic review

Maturitas ◽  
2013 ◽  
Vol 76 (2) ◽  
pp. 113-117 ◽  
Author(s):  
Kim Blom ◽  
Mariëlle H. Emmelot-Vonk ◽  
Huiberdina (Dineke) L. Koek
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Cognitive Decline ◽  
Vascular Risk Factors ◽  
Vascular Risk

scholarly journals Vascular Risk Factors and Cognitive Decline in a Population Sample

2014 ◽  
Vol 28 (1) ◽  
pp. 9-15 ◽  
Author(s):  
Mary Ganguli ◽  
Bo Fu ◽  
Beth E. Snitz ◽  
Frederick W. Unverzagt ◽  
David A. Loewenstein ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cognitive Decline ◽  
Population Sample ◽  
Vascular Risk Factors ◽  
Vascular Risk

scholarly journals O3-09-05: VASCULAR RISK FACTORS AND CSF AD BIOMARKERS ARE INDEPENDENTLY ASSOCIATED WITH COGNITIVE DECLINE

2019 ◽  
Vol 15 ◽  
pp. P906-P907
Author(s):  
Corinne Pettigrew ◽  
Anja Soldan ◽  
Jiangxia Wang ◽  
Mei-Cheng Wang ◽  
Rebecca F. Gottesman ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cognitive Decline ◽  
Vascular Risk Factors ◽  
Vascular Risk

S2-01-01: Role of vascular risk factors in cognitive decline beginning in middle age

2007 ◽  
Vol 3 (3S_Part_3) ◽  
pp. S179-S180
Author(s):  
David S. Knopman ◽  
Diane J. Catellier ◽  
Laura H. Coker ◽  
Thomas H. Mosley
Keyword(s):  
Risk Factors ◽  
Cognitive Decline ◽  
Middle Age ◽  
Vascular Risk Factors ◽  
Vascular Risk

scholarly journals Cortical atrophy mediates the accumulating effects of vascular risk factors on cognitive decline in the Alzheimer’s disease spectrum

Aging ◽  
2020 ◽  
Vol 12 (14) ◽  
pp. 15058-15076
Author(s):  
Qing Wang ◽  
Cancan He ◽  
Yao Zhu ◽  
Qianqian Zhang ◽  
Zhijun Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Decline ◽  
Vascular Risk Factors ◽  
Cortical Atrophy ◽  
Vascular Risk ◽  
Disease Spectrum
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