Effects of uni- and bilateral destructions of the caudate nucleus head by kainic acid on electroencephalogram in the wakefulness—sleep cycle in wistar rats

2000 ◽  
Vol 36 (2) ◽  
pp. 155-160 ◽  
Author(s):  
S. I. Vataev ◽  
G. A. Oganesyan
Keyword(s):  
Caudate Nucleus ◽  
Kainic Acid ◽  
Wistar Rats ◽  
Sleep Cycle ◽  
Caudate Nucleus Head

Lipid peroxidation in hippocampus early and late after status epilepticus induced by pilocarpine or kainic acid in Wistar rats

2000 ◽  
Vol 291 (3) ◽  
pp. 179-182 ◽  
Author(s):  
Felipe Dal-Pizzol ◽  
Fábio Klamt ◽  
Mônica M.R Vianna ◽  
Nadia Schröder ◽  
João Quevedo ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Status Epilepticus ◽  
Kainic Acid ◽  
Wistar Rats

scholarly journals Subconvulsive Dose of Kainic Acid Transiently Increases the Locomotor Activity of Adult Wistar Rats

2015 ◽  
pp. 263-267 ◽  
Author(s):  
V. RILJAK ◽  
D. MAREŠOVÁ ◽  
J. POKORNÝ ◽  
K. JANDOVÁ
Keyword(s):  
Open Field ◽  
Kainic Acid ◽  
Field Test ◽  
Wistar Rats ◽  
Open Field Test ◽  
Neuronal Degeneration ◽  
Neuronal Damage ◽  
Fluoro Jade B ◽  
Behavioral Parameters ◽  
Convulsive Seizures

Kainic acid (KA) is a potent neurotoxic substance valuable in research of temporal lobe epilepsy. We tested how subconvulsive dose of KA influences spontaneous behavior of adult Wistar rats. Animals were treated with 5 mg/kg of KA and tested in Laboras open field test for one hour in order to evaluate various behavioral parameters. Week after the KA treatment animals were tested again in Laboras open field test. Finally, rat’s brains were sliced and stained with Fluoro-Jade B to detect possible neuronal degeneration. Treatment with KA increased the time spent by locomotion (p<0.01), exploratory rearing (p<0.05) and animals traveled longer distance (p<0.01). These parameters tended to increase thirty minutes after KA administration. Week after the treatment we did not found differences in any measured behavioral parameter. Histology in terms of Fluoro-Jade B staining did not reveal any obvious neuronal damage in hippocampus. These results demonstrate that subconvulsive KA dose changes the behavioral parameters only transiently. Clarification of timing of the KA induced changes may contribute to understand mutual relationship between non-convulsive seizures and behavioral/cognitive consequences.

Changes in lipid composition in hippocampus early and late after status epilepticus induced by kainic acid in wistar rats

2006 ◽  
Vol 22 (1) ◽  
pp. 25-29 ◽  
Author(s):  
Felipe Dal-Pizzol ◽  
João Quevedo ◽  
Emílio Streck ◽  
Roger Walz ◽  
José Cláudio F. Moreira
Keyword(s):  
Status Epilepticus ◽  
Kainic Acid ◽  
Lipid Composition ◽  
Wistar Rats

scholarly journals Differences in neurodegeneration between kainic acid-injected gaers and wistar rats

2018 ◽  
Author(s):  
Umit S. Sehirli ◽  
Ozlem Kirazli ◽  
Kutluhan Tezcan ◽  
Eren Sakalli ◽  
Filiz Onat
Keyword(s):  
Kainic Acid ◽  
Wistar Rats
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